{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T21:23:57Z","timestamp":1772400237372,"version":"3.50.1"},"reference-count":24,"publisher":"Walter de Gruyter GmbH","issue":"4","license":[{"start":{"date-parts":[[2020,11,2]],"date-time":"2020-11-02T00:00:00Z","timestamp":1604275200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,11,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_pp-2020-0131_abs_001_w2aab3b7c16b1b6b1aab1c14b1Aa\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Local anesthetic medical thoracoscopy (LAT) is a well-established diagnostic, therapeutic, and preventative intervention in undiagnosed pleural effusions with a high diagnostic sensitivity and low complication rates. There is a large variability in practice. We describe a nine-year experience in a large district general hospital in England.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_pp-2020-0131_abs_002_w2aab3b7c16b1b6b1aab1c14b2Aa\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Two hundred seventy-five patients had LAT between January 2010 and December 2018. Data on outcomes and complications were obtained from the patients\u2019 notes, electronic records, laboratory, and radiographic findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_pp-2020-0131_abs_003_w2aab3b7c16b1b6b1aab1c14b3Aa\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The main diagnoses were malignant pleural mesothelioma (MPM) (n=110, 40%), chronic inflammation\/fibrinous pleuritis (77, 28%), lung cancer (26, 9.5%), and breast cancer (16, 6%). LAT failed to diagnose cancer in 7\/275 patients (false-negative rate 2.5%, diagnostic sensitivity 97.5%). Out of the 105 patients with chronic inflammation\/fibrinous pleuritis or atypical proliferative processes, 21 (20%) were subsequently diagnosed with malignancy. Talcum pleurodesis was performed in 146 patients, and was successful in 86%. Seventy eight (28%) patients had trapped lung; 27 of those had a repeat procedure. The median length of stay was 3.96\u00a0days. There was one hospital death (0.3% mortality). Complications of LAT included pleural (3, 1%) and wound infections (4, 1.4%), persistent air leaks (9, 3.2%), subcutaneous emphysema (10, 3.6%), and tumor extension to the access port (1, 0.3%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_pp-2020-0131_abs_004_w2aab3b7c16b1b6b1aab1c14b4Aa\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this cohort, LAT was safe, effective, and enabled high diagnostic sensitivity. Further areas of study include optimal sedation and anesthetic pathways and combining LAT with indwelling pleural catheters (IPC).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/pp-2020-0131","type":"journal-article","created":{"date-parts":[[2020,11,3]],"date-time":"2020-11-03T10:20:13Z","timestamp":1604398813000},"source":"Crossref","is-referenced-by-count":17,"title":["A review of the outcomes of rigid medical thoracoscopy in a large UK district general hospital"],"prefix":"10.1515","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0859-5550","authenticated-orcid":false,"given":"Avinash","family":"Aujayeb","sequence":"first","affiliation":[{"name":"Northumbria HealthCare NHS Foundation Trust, Care of Tracy Groom , Cramlington , Northumberland , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6464-7474","authenticated-orcid":false,"given":"Karl","family":"Jackson","sequence":"additional","affiliation":[{"name":"Northumbria HealthCare NHS Foundation Trust, Care of Tracy Groom , Cramlington , Northumberland , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2020,11,2]]},"reference":[{"key":"2025120909220890523_j_pp-2020-0131_ref_001_w2aab3b7c16b1b6b1ab2b1b1Aa","doi-asserted-by":"crossref","unstructured":"Hoksch, B, Birken-Bertsch, H, M\u00fcller, JMD. Thoracoscopy before Jacobaeus. Ann Thorac Surg 2002;74:P1288\u201390. https:\/\/doi.org\/10.1016\/s0003-4975(02)03676-7.","DOI":"10.1016\/S0003-4975(02)03676-7"},{"key":"2025120909220890523_j_pp-2020-0131_ref_002_w2aab3b7c16b1b6b1ab2b1b2Aa","doi-asserted-by":"crossref","unstructured":"Rahman, N, Ali, N, Brown, G, Chapman, SJ, Davies, RJO, Downer, NJ, et al. Local anaesthetic thoracoscopy: British Thoracic Society pleural disease guideline 2010. Thorax 2010;65:ii54\u201360. https:\/\/doi.org\/10.1136\/thx.2010.137018.","DOI":"10.1136\/thx.2010.137018"},{"key":"2025120909220890523_j_pp-2020-0131_ref_003_w2aab3b7c16b1b6b1ab2b1b3Aa","doi-asserted-by":"crossref","unstructured":"Tsim, S, Paterson, S, Cartwright, D, Fong, CJ, Alexander, L, Kelly, C, et al. Baseline predictors of negative and incomplete pleural cytology in patients with suspected pleural malignancy \u2013 data supporting \u2018Direct to LAT\u2019 in selected groups. 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