{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:53:51Z","timestamp":1792788831180,"version":"4.5.0"},"reference-count":46,"publisher":"Walter de Gruyter GmbH","issue":"2","license":[{"start":{"date-parts":[[2022,4,21]],"date-time":"2022-04-21T00:00:00Z","timestamp":1650499200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"AM-ETHOS Duke-NUS Medical Student Fellowship Award"},{"name":"NCCS Cancer Fund"},{"name":"SingHealth Duke-NUS Academic Medicine Centre"},{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","award":["CIRG21jun-0038"],"award-info":[{"award-number":["CIRG21jun-0038"]}],"id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,6,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_pp-2021-0154_abs_001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Pressurized intraperitoneal aerosol chemotherapy (PIPAC) has recently emerged as a palliative alternative for patients with unresectable peritoneal metastasis (PM). Quality of life (QoL) has increasingly been used as an endpoint to evaluate treatment outcomes. This review aims to identify evidence on how PIPAC would impact the QoL of PM patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_pp-2021-0154_abs_002\">\n                    <jats:title>Content<\/jats:title>\n                    <jats:p>A systematic review was performed on articles identified from Medline, EMBASE, PsycInfo, and Web of Sciences. A meta-analysis was conducted on further selected studies. ACROBAT-NRSI was attempted to assess the risk of bias (RoB).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_pp-2021-0154_abs_003\">\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>Nine studies using the EORTC QLQ-C30 questionnaire to assess QoL after repeated PIPAC cycles were identified. Majority was found to be moderately biased and a great extent of heterogeneity was observed. Four studies on PM from either gastric cancer (GC) or epithelial ovarian cancer (EOC) were included for meta-analysis. In 31\u00a0GC patients and 104 EOC patients, QoL remained stable in 13\/14 and 11\/14 EORTC QLQ-C30 scales. PIPAC was inferior to cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS\/HIPEC) in global QoL and functioning but superior in symptom reduction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_pp-2021-0154_abs_004\">\n                    <jats:title>Outlook<\/jats:title>\n                    <jats:p>PIPAC is a well-tolerated option for most GC and EOC patients with irresectable PM. Future trials are warranted to confirm the findings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/pp-2021-0154","type":"journal-article","created":{"date-parts":[[2022,4,21]],"date-time":"2022-04-21T11:26:34Z","timestamp":1650540394000},"page":"39-49","source":"Crossref","is-referenced-by-count":22,"title":["A systematic review on quality of life (QoL) of patients with peritoneal metastasis (PM) who underwent pressurized intraperitoneal aerosol chemotherapy (PIPAC)"],"prefix":"10.1515","volume":"7","author":[{"given":"Zhenyue","family":"Li","sequence":"first","affiliation":[{"name":"Department of Sarcoma , Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore , Singapore , Singapore"},{"name":"Department of Sarcoma , Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, Singapore General Hospital , Singapore , Singapore"},{"name":"Duke-NUS Medical School , Singapore , Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis Choon Kit","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Sarcoma , Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore , Singapore , Singapore"},{"name":"Department of Sarcoma , Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, Singapore General Hospital , Singapore , Singapore"},{"name":"Duke-NUS Medical School , Singapore , Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rehena","family":"Sultana","sequence":"additional","affiliation":[{"name":"Duke-NUS Medical School , Singapore , Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8114-1280","authenticated-orcid":false,"given":"Hui Jun","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Sarcoma , Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore , Singapore , Singapore"},{"name":"Department of Sarcoma , Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, Singapore General Hospital , Singapore , Singapore"},{"name":"Laboratory of Applied Human Genetics, Division of Medical Sciences, National Cancer Centre Singapore , Singapore , Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6620-6085","authenticated-orcid":false,"given":"Joey Wee-Shan","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Sarcoma , Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore , Singapore , Singapore"},{"name":"Department of Sarcoma , Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, Singapore General Hospital , Singapore , Singapore"},{"name":"Laboratory of Applied Human Genetics, Division of Medical Sciences, National Cancer Centre Singapore , Singapore , Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5700-1739","authenticated-orcid":false,"given":"Qiu Xuan","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Sarcoma , Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore , Singapore , Singapore"},{"name":"Department of Sarcoma , Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, Singapore General Hospital , Singapore , Singapore"},{"name":"Laboratory of Applied Human Genetics, Division of Medical Sciences, National Cancer Centre Singapore , Singapore , Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9750-5755","authenticated-orcid":false,"given":"Jolene Si Min","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Sarcoma , Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore , Singapore , Singapore"},{"name":"Department of Sarcoma , Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, Singapore General Hospital , Singapore , Singapore"},{"name":"SingHealth Duke-NUS Oncology Academic Clinical Program, Duke NUS Medical School , Singapore , Singapore"},{"name":"SingHealth Duke-NUS Surgery Academic Clinical Program, Duke NUS Medical School , Singapore , Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5540-2646","authenticated-orcid":false,"given":"Claramae Shulyn","family":"Chia","sequence":"additional","affiliation":[{"name":"Department of Sarcoma , Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore , Singapore , Singapore"},{"name":"Department of Sarcoma , Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, Singapore General Hospital , Singapore , Singapore"},{"name":"SingHealth Duke-NUS Oncology Academic Clinical Program, Duke NUS Medical School , Singapore , Singapore"},{"name":"SingHealth Duke-NUS Surgery Academic Clinical Program, Duke NUS Medical School , Singapore , Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4573-7738","authenticated-orcid":false,"given":"Chin-Ann Johnny","family":"Ong","sequence":"additional","affiliation":[{"name":"Department of Sarcoma , Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore , Singapore , Singapore"},{"name":"Department of Sarcoma , Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, Singapore General Hospital , Singapore , Singapore"},{"name":"Laboratory of Applied Human Genetics, Division of Medical Sciences, National Cancer Centre Singapore , Singapore , Singapore"},{"name":"SingHealth Duke-NUS Oncology Academic Clinical Program, Duke NUS Medical School , Singapore , Singapore"},{"name":"SingHealth Duke-NUS Surgery Academic Clinical Program, Duke NUS Medical School , Singapore , Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2022,4,21]]},"reference":[{"key":"2025120909241451378_j_pp-2021-0154_ref_001","doi-asserted-by":"crossref","unstructured":"Coccolini, F, Gheza, F, Lotti, M, Virzi, S, Iusco, D, Ghermandi, C, et al.. Peritoneal carcinomatosis. World J Gastroenterol 2013;19:6979\u201394. https:\/\/doi.org\/10.3748\/wjg.v19.i41.6979.","DOI":"10.3748\/wjg.v19.i41.6979"},{"key":"2025120909241451378_j_pp-2021-0154_ref_002","doi-asserted-by":"crossref","unstructured":"de Bree, E, Michelakis, D, Stamatiou, D, Romanos, J, Zoras, O. Pharmacological principles of intraperitoneal and bidirectional chemotherapy. Pleura Peritoneum 2017;2:47\u201362. https:\/\/doi.org\/10.1515\/pp-2017-0010.","DOI":"10.1515\/pp-2017-0010"},{"key":"2025120909241451378_j_pp-2021-0154_ref_003","doi-asserted-by":"crossref","unstructured":"Sugarbaker, PH, Stuart, OA, Vidal-Jove, J, Pessagno, AM, DeBruijn, EA. Pharmacokinetics of the peritoneal-plasma barrier after systemic mitomycin C administration. Cancer Treat Res 1996;82:41\u201352. https:\/\/doi.org\/10.1007\/978-1-4613-1247-5_3.","DOI":"10.1007\/978-1-4613-1247-5_3"},{"key":"2025120909241451378_j_pp-2021-0154_ref_004","doi-asserted-by":"crossref","unstructured":"Reymond, M, Solass, W. Pressurized intraperitoneal aerosol chemotherapy\u00a0\u2013 cancer under pressure. Walter de Gruyter GmbH; 2014.","DOI":"10.1201\/b19409-35"},{"key":"2025120909241451378_j_pp-2021-0154_ref_005","unstructured":"Desai, JP, Moustarah, F. Cancer, peritoneal metastasis. Treasure Island (FL): StatPearls; 2020."},{"key":"2025120909241451378_j_pp-2021-0154_ref_006","doi-asserted-by":"crossref","unstructured":"Sadeghi, B, Arvieux, C, Glehen, O, Beaujard, AC, Rivoire, M, Baulieux, J, et al.. Peritoneal carcinomatosis from non-gynecologic malignancies: results of the EVOCAPE 1 multicentric prospective study. Cancer 2000;88:358\u201363. https:\/\/doi.org\/10.1002\/(sici)1097-0142(20000115)88:2<358::aid-cncr16>3.0.co;2-o.","DOI":"10.1002\/(SICI)1097-0142(20000115)88:2<358::AID-CNCR16>3.0.CO;2-O"},{"key":"2025120909241451378_j_pp-2021-0154_ref_007","doi-asserted-by":"crossref","unstructured":"Bhatt, A. Management of peritoneal metastases\u00a0\u2013 cytoreductive surgery, HIPEC and beyond. Springer; 2018.","DOI":"10.1007\/978-981-10-7053-2"},{"key":"2025120909241451378_j_pp-2021-0154_ref_008","doi-asserted-by":"crossref","unstructured":"Prigerson, HG, Bao, Y, Shah, MA, Paulk, ME, LeBlanc, TW, Schneider, BJ, et al.. Chemotherapy use, performance status, and quality of life at the end of life. JAMA Oncol 2015;1:778\u201384. https:\/\/doi.org\/10.1001\/jamaoncol.2015.2378.","DOI":"10.1001\/jamaoncol.2015.2378"},{"key":"2025120909241451378_j_pp-2021-0154_ref_009","doi-asserted-by":"crossref","unstructured":"Patil, JS, Sarasija, S. Pulmonary drug delivery strategies: a concise, systematic review. Lung India 2012;29:44\u20139. https:\/\/doi.org\/10.4103\/0970-2113.92361.","DOI":"10.4103\/0970-2113.92361"},{"key":"2025120909241451378_j_pp-2021-0154_ref_010","doi-asserted-by":"crossref","unstructured":"Staquet, M, Berzon, R, Osoba, D, Machin, D. Guidelines for reporting results of quality of life assessments in clinical trials. Qual Life Res 1996;5:496\u2013502. https:\/\/doi.org\/10.1007\/bf00540022.","DOI":"10.1007\/BF00540022"},{"key":"2025120909241451378_j_pp-2021-0154_ref_011","doi-asserted-by":"crossref","unstructured":"Bratt, EL, Moons, P. Forty years of quality-of-life research in congenital heart disease: temporal trends in conceptual and methodological rigor. Int J Cardiol 2015;195:1\u20136. https:\/\/doi.org\/10.1016\/j.ijcard.2015.05.070.","DOI":"10.1016\/j.ijcard.2015.05.070"},{"key":"2025120909241451378_j_pp-2021-0154_ref_012","doi-asserted-by":"crossref","unstructured":"Haraldstad, K, Wahl, A, Andenaes, R, Andersen, JR, Andersen, MH, Beisland, E, et al.. A systematic review of quality of life research in medicine and health sciences. Qual Life Res 2019;28:2641\u201350. https:\/\/doi.org\/10.1007\/s11136-019-02214-9.","DOI":"10.1007\/s11136-019-02214-9"},{"key":"2025120909241451378_j_pp-2021-0154_ref_013","doi-asserted-by":"crossref","unstructured":"Moher, DLA, Tetzlaff, J, Altman, DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Int J Surg 2010;8:336\u201341. https:\/\/doi.org\/10.1016\/j.ijsu.2010.02.007.","DOI":"10.1016\/j.ijsu.2010.02.007"},{"key":"2025120909241451378_j_pp-2021-0154_ref_014","unstructured":"IOM (Institute of Medicine). Finding what works in health care: standards for systematic reviews. Washington, DC: The National Academies Press; 2011."},{"key":"2025120909241451378_j_pp-2021-0154_ref_015","doi-asserted-by":"crossref","unstructured":"Gockel, I, Jansen-Winkeln, B, Haase, L, Rhode, P, Mehdorn, M, Niebisch, S, et al.. Pressurized intraperitoneal aerosol chemotherapy (PIPAC) in gastric cancer patients with peritoneal metastasis (PM): results of a single-center experience and register study. J Gastric Cancer 2018;18:379\u201391. https:\/\/doi.org\/10.5230\/jgc.2018.18.e37.","DOI":"10.5230\/jgc.2018.18.e37"},{"key":"2025120909241451378_j_pp-2021-0154_ref_016","doi-asserted-by":"crossref","unstructured":"Struller, F, Horvath, P, Solass, W, Weinreich, FJ, Strumberg, D, Kokkalis, MK, et al.. Pressurized intraperitoneal aerosol chemotherapy with low-dose cisplatin and doxorubicin (PIPAC C\/D) in patients with gastric cancer and peritoneal metastasis: a phase II study. Ther Adv Med Oncol 2019;11:1758835919846402. https:\/\/doi.org\/10.1177\/1758835919846402.","DOI":"10.1177\/1758835919846402"},{"key":"2025120909241451378_j_pp-2021-0154_ref_017","doi-asserted-by":"crossref","unstructured":"Tempfer, CB, Rezniczek, GA, Ende, P, Solass, W, Reymond, MA. Pressurized intraperitoneal aerosol chemotherapy with cisplatin and doxorubicin in women with peritoneal carcinomatosis: a cohort study. Anticancer Res 2015;35:6723\u20139. https:\/\/doi.org\/10.1055\/s-0035-1560004.","DOI":"10.1055\/s-0035-1560004"},{"key":"2025120909241451378_j_pp-2021-0154_ref_018","doi-asserted-by":"crossref","unstructured":"Tempfer, CB, Winnekendonk, G, Solass, W, Horvat, R, Giger-Pabst, U, Zieren, J, et al.. Pressurized intraperitoneal aerosol chemotherapy in women with recurrent ovarian cancer: a phase 2 study. Gynecol Oncol 2015;137:223\u20138. https:\/\/doi.org\/10.1016\/j.ygyno.2015.02.009.","DOI":"10.1016\/j.ygyno.2015.02.009"},{"key":"2025120909241451378_j_pp-2021-0154_ref_019","doi-asserted-by":"crossref","unstructured":"Tan, WJ, Wong, JF, Chia, CS, Tan, GH, Soo, KC, Teo, MC. Quality of life after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: an Asian perspective. Ann Surg Oncol 2013;20:4219\u201323. https:\/\/doi.org\/10.1245\/s10434-013-3133-0.","DOI":"10.1245\/s10434-013-3133-0"},{"key":"2025120909241451378_j_pp-2021-0154_ref_020","unstructured":"Sterne, J, Higgins, J, Reeves, B. A Cochrane risk of bias assessment tool: for non-randomized studies of interventions (ACROBAT-NRSI). Version 1.0.0; 2014. Available from: http:\/\/www.riskofbias.info.2014."},{"key":"2025120909241451378_j_pp-2021-0154_ref_021","doi-asserted-by":"crossref","unstructured":"Odendahl, K, Solass, W, Demtroder, C, Giger-Pabst, U, Zieren, J, Tempfer, C, et al.. Quality of life of patients with end-stage peritoneal metastasis treated with Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC). Eur J Surg Oncol 2015;41:1379\u201385. https:\/\/doi.org\/10.1016\/j.ejso.2015.06.001.","DOI":"10.1016\/j.ejso.2015.06.001"},{"key":"2025120909241451378_j_pp-2021-0154_ref_022","doi-asserted-by":"crossref","unstructured":"Farinha, HT, Grass, F, Kefleyesus, A, Achtari, C, Romain, B, Montemurro, M, et al.. Impact of pressurized intraperitoneal aerosol chemotherapy on quality of life and symptoms in patients with peritoneal carcinomatosis: a retrospective cohort study. Gastroenterol Res Pract 2017;2017:4596176. https:\/\/doi.org\/10.1155\/2017\/4596176.","DOI":"10.1155\/2017\/4596176"},{"key":"2025120909241451378_j_pp-2021-0154_ref_023","doi-asserted-by":"crossref","unstructured":"Graversen, M, Detlefsen, S, Bjerregaard, JK, Fristrup, CW, Pfeiffer, P, Mortensen, MB. Prospective, single-center implementation and response evaluation of pressurized intraperitoneal aerosol chemotherapy (PIPAC) for peritoneal metastasis. Ther Adv Med Oncol 2018;10:1758835918777036. https:\/\/doi.org\/10.1177\/1758835918777036.","DOI":"10.1177\/1758835918777036"},{"key":"2025120909241451378_j_pp-2021-0154_ref_024","doi-asserted-by":"crossref","unstructured":"Giger-Pabst, U, Demtroder, C, Falkenstein, TA, Ouaissi, M, Gotze, TO, Rezniczek, GA, et al.. Pressurized IntraPeritoneal aerosol chemotherapy (PIPAC) for the treatment of malignant mesothelioma. BMC Cancer 2018;18:442. https:\/\/doi.org\/10.1186\/s12885-018-4363-0.","DOI":"10.1186\/s12885-018-4363-0"},{"key":"2025120909241451378_j_pp-2021-0154_ref_025","doi-asserted-by":"crossref","unstructured":"Robella, M, Vaira, M, De Simone, M. Safety and feasibility of pressurized intraperitoneal aerosol chemotherapy (PIPAC) associated with systemic chemotherapy: an innovative approach to treat peritoneal carcinomatosis. World J Surg Oncol 2016;14:128. https:\/\/doi.org\/10.1186\/s12957-016-0892-7.","DOI":"10.1186\/s12957-016-0892-7"},{"key":"2025120909241451378_j_pp-2021-0154_ref_026","doi-asserted-by":"crossref","unstructured":"Demtr\u00f6der, C, Solass, W, Zieren, J, Strumberg, D, Giger-Pabst, U, Reymond, MA. Pressurized intraperitoneal aerosol chemotherapy with oxaliplatin in colorectal peritoneal metastasis. Colorectal Dis 2016;18:364\u201371. https:\/\/doi.org\/10.1111\/codi.13130.","DOI":"10.1111\/codi.13130"},{"key":"2025120909241451378_j_pp-2021-0154_ref_027","doi-asserted-by":"crossref","unstructured":"Nadiradze, G, Giger-Pabst, U, Zieren, J, Strumberg, D, Solass, W, Reymond, MA. Pressurized intraperitoneal aerosol chemotherapy (PIPAC) with low-dose cisplatin and doxorubicin in gastric peritoneal metastasis. J Gastrointest Surg 2016;20:367\u201373. https:\/\/doi.org\/10.1007\/s11605-015-2995-9.","DOI":"10.1007\/s11605-015-2995-9"},{"key":"2025120909241451378_j_pp-2021-0154_ref_028","doi-asserted-by":"crossref","unstructured":"Yeung, CH, Santesso, N, Pai, M, Kessler, C, Key, NS, Makris, M, et al.. Care models in the management of haemophilia: a systematic review. Haemophilia 2016;22(Suppl 3):31\u201340. https:\/\/doi.org\/10.1111\/hae.13000.","DOI":"10.1111\/hae.13000"},{"key":"2025120909241451378_j_pp-2021-0154_ref_029","doi-asserted-by":"crossref","unstructured":"Vollam, S, Dutton, S, Lamb, S, Petrinic, T, Young, JD, Watkinson, P. Out-of-hours discharge from intensive care, in-hospital mortality and intensive care readmission rates: a systematic review and meta-analysis. Intensive Care Med 2018;44:1115\u201329. https:\/\/doi.org\/10.1007\/s00134-018-5245-2.","DOI":"10.1007\/s00134-018-5245-2"},{"key":"2025120909241451378_j_pp-2021-0154_ref_030","doi-asserted-by":"crossref","unstructured":"Synnot, A, Karlsson, A, Brichko, L, Chee, M, Fitzgerald, M, Misra, MC, et al.. Prehospital notification for major trauma patients requiring emergency hospital transport: a systematic review. J Evid Based Med 2017;10:212\u201321. https:\/\/doi.org\/10.1111\/jebm.12256.","DOI":"10.1111\/jebm.12256"},{"key":"2025120909241451378_j_pp-2021-0154_ref_031","doi-asserted-by":"crossref","unstructured":"Saramago, P, Yang, H, Llewellyn, A, Palmer, S, Simmonds, M, Griffin, S. High-throughput, non-invasive prenatal testing for fetal Rhesus D genotype to guide antenatal prophylaxis with anti-D immunoglobulin: a cost-effectiveness analysis. BJOG 2018;125:1414\u201322. https:\/\/doi.org\/10.1111\/1471-0528.15152.","DOI":"10.1111\/1471-0528.15152"},{"key":"2025120909241451378_j_pp-2021-0154_ref_032","doi-asserted-by":"crossref","unstructured":"Ryan, V, Brown, H, Minns Lowe, CJ, Lewis, JS. The pathophysiology associated with primary (idiopathic) frozen shoulder: a systematic review. BMC Muscoskel Disord 2016;17:340. https:\/\/doi.org\/10.1186\/s12891-016-1190-9.","DOI":"10.1186\/s12891-016-1190-9"},{"key":"2025120909241451378_j_pp-2021-0154_ref_033","doi-asserted-by":"crossref","unstructured":"Rocha, BDD, Zamberlan, C, Pivetta, HMF, Santos, BZ, Antunes, BS. Upright positions in childbirth and the prevention of perineal lacerations: a systematic review and meta-analysis. Rev Esc Enferm USP 2020;54:e03610. https:\/\/doi.org\/10.1590\/S1980-220X2018027503610.","DOI":"10.1590\/s1980-220x2018027503610"},{"key":"2025120909241451378_j_pp-2021-0154_ref_034","doi-asserted-by":"crossref","unstructured":"Pollock, M, Somerville, L, Firth, A, Lanting, B. Outpatient total hip arthroplasty, total knee arthroplasty, and unicompartmental knee arthroplasty: a systematic review of the literature. JBJS Rev 2016;4. https:\/\/doi.org\/10.2106\/JBJS.RVW.16.00002.","DOI":"10.2106\/JBJS.RVW.16.00002"},{"key":"2025120909241451378_j_pp-2021-0154_ref_035","doi-asserted-by":"crossref","unstructured":"le Roux, SM, Abrams, EJ, Nguyen, K, Myer, L. Clinical outcomes of HIV-exposed, HIV-uninfected children in sub-Saharan Africa. Trop Med Int Health 2016;21:829\u201345. https:\/\/doi.org\/10.1111\/tmi.12716.","DOI":"10.1111\/tmi.12716"},{"key":"2025120909241451378_j_pp-2021-0154_ref_036","doi-asserted-by":"crossref","unstructured":"Kotronias, RA, Scarsini, R, Rajasundaram, S, De Maria, GL, Ciofani, JL, Ribichini, F, et al.. Transcatheter aortic valve replacement influence on coronary hemodynamics: a quantitative meta-analysis and proposed decision-making algorithm. J Invasive Cardiol 2020;32:37\u201340.","DOI":"10.25270\/jic\/19.00284"},{"key":"2025120909241451378_j_pp-2021-0154_ref_037","doi-asserted-by":"crossref","unstructured":"Kalkhoran, S, Glantz, SA. E-cigarettes and smoking cessation in real-world and clinical settings: a systematic review and meta-analysis. Lancet Respir Med 2016;4:116\u201328. https:\/\/doi.org\/10.1016\/s2213-2600(15)00521-4.","DOI":"10.1016\/S2213-2600(15)00521-4"},{"key":"2025120909241451378_j_pp-2021-0154_ref_038","doi-asserted-by":"crossref","unstructured":"Jiang, J, Kang, N, Li, B, Wu, AS, Xue, FS. Comparison of adverse events between video and direct laryngoscopes for tracheal intubations in emergency department and ICU patients-a systematic review and meta-analysis. Scand J Trauma Resusc Emerg Med 2020;28:10. https:\/\/doi.org\/10.1186\/s13049-020-0702-7.","DOI":"10.1186\/s13049-020-0702-7"},{"key":"2025120909241451378_j_pp-2021-0154_ref_039","doi-asserted-by":"crossref","unstructured":"Hoechter, DJ, Shen, YM, Kammerer, T, G\u00fcnther, S, Weig, T, Schramm, R, et al.. Extracorporeal circulation during lung transplantation procedures: a meta-analysis. ASAIO J 2017;63:551\u201361. https:\/\/doi.org\/10.1097\/MAT.0000000000000549.","DOI":"10.1097\/MAT.0000000000000549"},{"key":"2025120909241451378_j_pp-2021-0154_ref_040","doi-asserted-by":"crossref","unstructured":"Heidemann, CH, Lous, J, Berg, J, Christensen, JJ, H\u00e5konsen, SJ, Jakobsen, M, et al.. Danish guidelines on management of otitis media in preschool children. Int J Pediatr Otorhinolaryngol 2016;87:154\u201363. https:\/\/doi.org\/10.1016\/j.ijporl.2016.06.003.","DOI":"10.1016\/j.ijporl.2016.06.003"},{"key":"2025120909241451378_j_pp-2021-0154_ref_041","doi-asserted-by":"crossref","unstructured":"Guarnieri, R, Bertoldo, S, Cassetta, M, Altieri, F, Grenga, C, Vichi, M, et al.. Periodontal results of different therapeutic approaches (open vs. closed technique) and timing evaluation (<2 year vs. >2 year) of palatal impacted canines: a systematic review. BMC Oral Health 2021;21:574. https:\/\/doi.org\/10.1186\/s12903-021-01937-x.","DOI":"10.1186\/s12903-021-01937-x"},{"key":"2025120909241451378_j_pp-2021-0154_ref_042","doi-asserted-by":"crossref","unstructured":"Fu, L, Chen, Y, Yang, X, Yang, Z, Liu, S, Pei, L, et al.. The associations of air pollution exposure during pregnancy with fetal growth and anthropometric measurements at birth: a systematic review and meta-analysis. Environ Sci Pollut Res Int 2019;26:20137\u201347. https:\/\/doi.org\/10.1007\/s11356-019-05338-0.","DOI":"10.1007\/s11356-019-05338-0"},{"key":"2025120909241451378_j_pp-2021-0154_ref_043","doi-asserted-by":"crossref","unstructured":"Benton, JS, Anderson, J, Hunter, RF, French, DP. The effect of changing the built environment on physical activity: a quantitative review of the risk of bias in natural experiments. Int J Behav Nutr Phys Activ 2016;13:107. https:\/\/doi.org\/10.1186\/s12966-016-0433-3.","DOI":"10.1186\/s12966-016-0433-3"},{"key":"2025120909241451378_j_pp-2021-0154_ref_044","doi-asserted-by":"crossref","unstructured":"Behzadifar, M, Sohrabi, R, Mohammadibakhsh, R, Salemi, M, Moghadam, ST, Taheri Mirghaedm, M, et al.. General health status in Iranian diabetic patients assessed by short-form-36 questionnaire: a systematic review and meta-analysis. BMC Endocr Disord 2018;18:34. https:\/\/doi.org\/10.1186\/s12902-018-0262-2.","DOI":"10.1186\/s12902-018-0262-2"},{"key":"2025120909241451378_j_pp-2021-0154_ref_045","doi-asserted-by":"crossref","unstructured":"Agrawal, K, Anwar, M, Gupta, C, Chand, P, Singh, S. Association of interleukin-1 gene polymorphism and early crestal bone loss around submerged dental implants: a systematic review and meta-analysis. J Indian Prosthodont Soc 2021;21:116\u201324. https:\/\/doi.org\/10.4103\/jips.jips_511_20.","DOI":"10.4103\/jips.jips_511_20"},{"key":"2025120909241451378_j_pp-2021-0154_ref_046","doi-asserted-by":"crossref","unstructured":"Bilandzic, A, Fitzpatrick, T, Rosella, L, Henry, D. Risk of bias in systematic reviews of non-randomized studies of adverse cardiovascular effects of thiazolidinediones and cyclooxygenase-2 inhibitors: application of a new Cochrane risk of bias tool. PLoS Med 2016;13:e1001987. https:\/\/doi.org\/10.1371\/journal.pmed.1001987.","DOI":"10.1371\/journal.pmed.1001987"}],"container-title":["Pleura and Peritoneum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/pp-2021-0154\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/pp-2021-0154\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T11:02:14Z","timestamp":1765278134000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/pp-2021-0154\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,21]]},"references-count":46,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2022,3,15]]},"published-print":{"date-parts":[[2022,6,3]]}},"alternative-id":["10.1515\/pp-2021-0154"],"URL":"https:\/\/doi.org\/10.1515\/pp-2021-0154","relation":{},"ISSN":["2364-768X"],"issn-type":[{"value":"2364-768X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,21]]}}}