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Every stage of the UOG lifecycle, from well construction to extraction, operations, transportation and distribution can lead to air and water contamination. Residents near UOG operations can suffer from increased exposure to elevated concentrations of air and water pollutants. Here we focus on five air and water pollutants that have been associated with potentially permanent learning and neuropsychological deficits, neurodevelopmental disorders and neurological birth defects. Given the profound sensitivity of the developing brain and central nervous system, it is reasonable to conclude that young children who experience frequent exposure to these pollutants are at particularly high risk for chronic neurological diseases. More research is needed to understand the extent of these concerns in the context of UOG, but since UOG development has expanded rapidly in recent years, the need for public health prevention techniques, well-designed studies and stronger state and national regulatory standards is becoming increasingly apparent.<\/jats:p>","DOI":"10.1515\/reveh-2017-0008","type":"journal-article","created":{"date-parts":[[2017,10,25]],"date-time":"2017-10-25T10:01:27Z","timestamp":1508925687000},"page":"3-29","source":"Crossref","is-referenced-by-count":51,"title":["Neurodevelopmental and neurological effects of chemicals associated with unconventional oil and natural gas operations and their potential effects on infants and children"],"prefix":"10.1515","volume":"33","author":[{"given":"Ellen","family":"Webb","sequence":"first","affiliation":[{"name":"Center for Environmental Health , 2201 Broadway, Suite 302 , Oakland , CA 94612, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Moon","sequence":"additional","affiliation":[{"name":"Columbia University , New York, NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larysa","family":"Dyrszka","sequence":"additional","affiliation":[{"name":"Physicians for Social Responsibility , Glen Spey, NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"University of California , Berkeley, Oakland, CA , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Cox","sequence":"additional","affiliation":[{"name":"Center for Environmental Health , Oakland, CA , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Patisaul","sequence":"additional","affiliation":[{"name":"North Carolina State University College of Sciences , Raleigh, NC , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila","family":"Bushkin","sequence":"additional","affiliation":[{"name":"Institute for Health and the Environment , Albany, NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"London","sequence":"additional","affiliation":[{"name":"Institute for Basic Research , New York, NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2017,10,25]]},"reference":[{"key":"2021021411371234447_j_reveh-2017-0008_ref_001_w2aab3b7c10b1b6b1ab2b2b1Aa","doi-asserted-by":"crossref","unstructured":"Colborn T, Kwiatkowski C, Schultz K, Bachran M. 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