{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T16:16:47Z","timestamp":1783613807852,"version":"3.55.0"},"reference-count":24,"publisher":"Walter de Gruyter GmbH","issue":"2","funder":[{"DOI":"10.13039\/501100009331","name":"Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support","doi-asserted-by":"publisher","award":["ZYLX201710"],"award-info":[{"award-number":["ZYLX201710"]}],"id":[{"id":"10.13039\/501100009331","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009601","name":"Beijing Municipal Administration of Hospitals\u2019 Ascent Plan","doi-asserted-by":"publisher","award":["DFL20180601"],"award-info":[{"award-number":["DFL20180601"]}],"id":[{"id":"10.13039\/501100009601","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Beijing Lab for Cardiovascular Precision Medicine","award":["PXM2018_014226_000013"],"award-info":[{"award-number":["PXM2018_014226_000013"]}]},{"DOI":"10.13039\/501100010270","name":"Capital Health Research and Development of Special Fund","doi-asserted-by":"publisher","award":["2018-1-2061"],"award-info":[{"award-number":["2018-1-2061"]}],"id":[{"id":"10.13039\/501100010270","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005090","name":"Beijing Nova Program","doi-asserted-by":"publisher","award":["Z201100006820087"],"award-info":[{"award-number":["Z201100006820087"]}],"id":[{"id":"10.13039\/501100005090","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,6,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_reveh-2021-0035_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Air pollution can lead to many cardiovascular and respiratory diseases, but the impact of air pollution on pulmonary embolism is still uncertain. We conducted a meta-analysis to assess the relationship between air pollution and pulmonary embolism.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_reveh-2021-0035_abs_002\">\n                    <jats:title>Content<\/jats:title>\n                    <jats:p>\n                      We searched PubMed, EMBASE, Web of Science, and the Cochran Library for citations on air pollutants (carbon monoxide, sulfur dioxide, nitrogen dioxide, ozone and particulate matter) and pulmonary embolism. A total of nine citations met the inclusion criteria. There is no evidence of bias. CO, SO\n                      <jats:sub>2<\/jats:sub>\n                      , PM\n                      <jats:sub>10<\/jats:sub>\n                      and PM\n                      <jats:sub>2.5<\/jats:sub>\n                      had no significant effect on the occurrence of pulmonary embolism. NO\n                      <jats:sub>2<\/jats:sub>\n                      and O\n                      <jats:sub>3<\/jats:sub>\n                      can increase the risk of pulmonary embolism to a small extent.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_reveh-2021-0035_abs_003\">\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>This meta-analysis suggests that some air pollutants are associated with an increased risk of pulmonary embolism.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_reveh-2021-0035_abs_004\">\n                    <jats:title>Outlook<\/jats:title>\n                    <jats:p>Reducing air pollution and improving air quality can effectively reduce the risk of pulmonary embolism.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/reveh-2021-0035","type":"journal-article","created":{"date-parts":[[2021,6,9]],"date-time":"2021-06-09T19:09:19Z","timestamp":1623265759000},"page":"259-266","source":"Crossref","is-referenced-by-count":8,"title":["Air pollution increases the risk of pulmonary embolism: a meta-analysis"],"prefix":"10.1515","volume":"37","author":[{"given":"Huangtai","family":"Miao","sequence":"first","affiliation":[{"name":"Beijing An Zhen Hospital , Chaoyang-qu , Beijing , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoying","family":"Li","sequence":"additional","affiliation":[{"name":"Beijing Jishuitan Hospital , Beijing , Beijing , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Wang","sequence":"additional","affiliation":[{"name":"Beijing An Zhen Hospital , Chaoyang-qu , Beijing , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaoping","family":"Nie","sequence":"additional","affiliation":[{"name":"Beijing An Zhen Hospital, 2 Anzhen Rd, Chaoyang District, 100029 , Chaoyang-qu , Beijing , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2021,6,9]]},"reference":[{"key":"2026070915585965736_j_reveh-2021-0035_ref_001","doi-asserted-by":"crossref","unstructured":"Cho, Y, Kang, H, Oh, J, Lim, TH, Ryu, J, Ko, BS. Risk of venous thromboembolism after carbon monoxide poisoning: a nationwide population-based study. Ann Emerg Med 2020;75:587\u201396. https:\/\/doi.org\/10.1016\/j.annemergmed.2019.08.454.","DOI":"10.1016\/j.annemergmed.2019.08.454"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_002","doi-asserted-by":"crossref","unstructured":"de Miguel-Diez, J, Jim\u00e9nez-Garc\u00eda, R, de Andr\u00e9s, AL, Hern\u00e1ndez-Barrera, V, Carrasco-Garrido, P, Monreal, M, et al.. Analysis of environmental risk factors for pulmonary embolism: a case-crossover study (2001\u20132013). Eur J Intern Med 2016;31:55\u201361. https:\/\/doi.org\/10.1016\/j.ejim.2016.03.001.","DOI":"10.1016\/j.ejim.2016.03.001"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_003","doi-asserted-by":"crossref","unstructured":"Chung, WS, Lin, CL, Kao, CH. Carbon monoxide poisoning and risk of deep vein thrombosis and pulmonary embolism: a nationwide retrospective cohort study. J Epidemiol Community Health 2015;69:557\u201362. https:\/\/doi.org\/10.1136\/jech-2014-205047.","DOI":"10.1136\/jech-2014-205047"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_004","doi-asserted-by":"crossref","unstructured":"Kloog, I, Zanobetti, A, Nordio, F, Coull, BA, Baccarelli, AA, Schwartz, J. Effects of airborne fine particles (PM2.5) on deep vein thrombosis admissions in the northeastern United States. J Thromb Haemostasis 2015;13:768\u201374. https:\/\/doi.org\/10.1111\/jth.12873.","DOI":"10.1111\/jth.12873"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_005","doi-asserted-by":"crossref","unstructured":"Pun, VC, Hart, JE, Kabrhel, C, Camargo Jr, CA, Baccarelli, AA, Laden, F. Prospective study of ambient particulate matter exposure and risk of pulmonary embolism in the nurses\u2019 health study cohort. Environ Health Perspect 2015;123:1265\u201370. https:\/\/doi.org\/10.1289\/ehp.1408927.","DOI":"10.1289\/ehp.1408927"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_006","doi-asserted-by":"crossref","unstructured":"Milojevic, A, Wilkinson, P, Armstrong, B, Bhaskaran, K, Smeeth, L, Hajat, S. Short-term effects of air pollution on a range of cardiovascular events in England and Wales: case-crossover analysis of the MINAP database, hospital admissions and mortality. Heart 2014;100:1093\u20138. https:\/\/doi.org\/10.1136\/heartjnl-2013-304963.","DOI":"10.1136\/heartjnl-2013-304963"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_007","doi-asserted-by":"crossref","unstructured":"Spiezia, L, Wilkinson, P, Armstrong, B, Bhaskaran, K, Smeeth, L, Hajat, S. Short-term exposure to high levels of air pollution as a risk factor for acute isolated pulmonary embolism. Thromb Res 2014;134:259\u201363. https:\/\/doi.org\/10.1016\/j.thromres.2014.05.011.","DOI":"10.1016\/j.thromres.2014.05.011"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_008","doi-asserted-by":"crossref","unstructured":"Dales, RE, Cakmak, S, Vidal, CB. Air pollution and hospitalization for venous thromboembolic disease in Chile. J Thromb Haemostasis 2010;8:669\u201374. https:\/\/doi.org\/10.1111\/j.1538-7836.2010.03760.x.","DOI":"10.1111\/j.1538-7836.2010.03760.x"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_009","unstructured":"Colais, P, Serinelli, M, Faustini, A, Stafoggia, M, Randi, G, Tessari, R, et al.. Air pollution and urgent hospital admissions in nine Italian cities. Results of the EpiAir Project. Epidemiol Prev 2009;33:77\u201394."},{"key":"2026070915585965736_j_reveh-2021-0035_ref_010","doi-asserted-by":"crossref","unstructured":"Franchini, M, Mannucci, PM. Thrombogenicity and cardiovascular effects of ambient air pollution. Blood 2011;118:2405\u201312. https:\/\/doi.org\/10.1182\/blood-2011-04-343111.","DOI":"10.1182\/blood-2011-04-343111"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_011","doi-asserted-by":"crossref","unstructured":"Xu, H, Wang, T, Liu, S, Brook, RD, Feng, B, Zhao, Q, et al.. Extreme levels of air pollution associated with changes in biomarkers of atherosclerotic plaque vulnerability and thrombogenicity in healthy adults. Circ Res 2019;124:e30\u201343. https:\/\/doi.org\/10.1161\/CIRCRESAHA.118.313948.","DOI":"10.1161\/CIRCRESAHA.118.313948"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_012","doi-asserted-by":"crossref","unstructured":"Peters, A, D\u00f6ring, A, Wichmann, HE, Koenig, W. Increased plasma viscosity during an air pollution episode: a link to mortality? Lancet 1997;349:1582\u20137. https:\/\/doi.org\/10.1016\/s0140-6736(97)01211-7.","DOI":"10.1016\/S0140-6736(97)01211-7"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_013","doi-asserted-by":"crossref","unstructured":"Park, SK, O\u2019Neill, MS, Vokonas, PS, Sparrow, D, Spiro III, A, Tucker, KL, et al.. Traffic-related particles are associated with elevated homocysteine: the VA normative aging study. Am J Respir Crit Care Med 2008;178:283\u20139. https:\/\/doi.org\/10.1164\/rccm.200708-1286oc.","DOI":"10.1164\/rccm.200708-1286OC"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_014","doi-asserted-by":"crossref","unstructured":"Rudez, G, Janssen, NA, Kilinc, E, Leebeek, FW, Gerlofs-Nijland, ME, Spronk, HM, et al.. Effects of ambient air pollution on hemostasis and inflammation. Environ Health Perspect 2009;117:995\u20131001. https:\/\/doi.org\/10.1289\/ehp.0800437.","DOI":"10.1289\/ehp.0800437"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_015","doi-asserted-by":"crossref","unstructured":"Cherng, TW, Campen, MJ, Knuckles, TL, Gonzalez Bosc, L, Kanagy, NL. Impairment of coronary endothelial cell ET(B) receptor function after short-term inhalation exposure to whole diesel emissions. Am J Physiol Regul Integr Comp Physiol 2009;297:R640-7. https:\/\/doi.org\/10.1152\/ajpregu.90899.2008.","DOI":"10.1152\/ajpregu.90899.2008"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_016","doi-asserted-by":"crossref","unstructured":"Zhao, Y, Xue, L, Chen, Q, Kou, M, Wang, Z, Wu, S, et al.. Cardiorespiratory responses to fine particles during ambient PM2.5 pollution waves: findings from a randomized crossover trial in young healthy adults. Environ Int 2020;139:105590. https:\/\/doi.org\/10.1016\/j.envint.2020.105590.","DOI":"10.1016\/j.envint.2020.105590"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_017","doi-asserted-by":"crossref","unstructured":"Zhang, Z, Chan, TC, Guo, C, Chang, LY, Lin, C, Chuang, YC, et al.. Long-term exposure to ambient particulate matter (PM2.5) is associated with platelet counts in adults. Environ Pollut 2018;240:432\u20139. https:\/\/doi.org\/10.1016\/j.envpol.2018.04.123.","DOI":"10.1016\/j.envpol.2018.04.123"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_018","doi-asserted-by":"crossref","unstructured":"Chen, R, Li, H, Cai, J, Wang, C, Lin, Z, Liu, C, et al.. Fine particulate air pollution and the expression of microRNAs and circulating cytokines relevant to inflammation, coagulation, and vasoconstriction. Environ Health Perspect 2018;126:017007. https:\/\/doi.org\/10.1289\/ehp1447.","DOI":"10.1289\/EHP1447"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_019","doi-asserted-by":"crossref","unstructured":"Baccarelli, A, Zanobetti, A, Martinelli, I, Grillo, P, Hou, L, Giacomini, S, et al.. Effects of exposure to air pollution on blood coagulation. J Thromb Haemostasis 2007;5:252\u201360. https:\/\/doi.org\/10.1111\/j.1538-7836.2007.02300.x.","DOI":"10.1111\/j.1538-7836.2007.02300.x"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_020","doi-asserted-by":"crossref","unstructured":"Mirowsky, JE, Carraway, MS, Dhingra, R, Tong, H, Neas, L, Diaz-Sanchez, D, et al.. Ozone exposure is associated with acute changes in inflammation, fibrinolysis, and endothelial cell function in coronary artery disease patients. Environ Health 2017;16:126. https:\/\/doi.org\/10.1186\/s12940-017-0335-0.","DOI":"10.1186\/s12940-017-0335-0"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_021","doi-asserted-by":"crossref","unstructured":"Liang, S, Zhao, T, Hu, H, Shi, Y, Xu, Q, Miller, MR, et al.. Repeat dose exposure of PM2.5 triggers the disseminated intravascular coagulation (DIC) in SD rats. Sci Total Environ 2019;663:245\u201353. https:\/\/doi.org\/10.1016\/j.scitotenv.2019.01.346.","DOI":"10.1016\/j.scitotenv.2019.01.346"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_022","doi-asserted-by":"crossref","unstructured":"Emmerechts, J, Alfaro\u2010Moreno, E, Vanaudenaerde, BM, Nemery, B, Hoylaerts, MF. Short-term exposure to particulate matter induces arterial but not venous thrombosis in healthy mice. J Thromb Haemostasis 2010;8:2651\u201361. https:\/\/doi.org\/10.1111\/j.1538-7836.2010.04081.x.","DOI":"10.1111\/j.1538-7836.2010.04081.x"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_023","doi-asserted-by":"crossref","unstructured":"Rich, DQ, Freudenberger, RS, Ohman-Strickland, P, Cho, Y, Kipen, HM. Right heart pressure increases after acute increases in ambient particulate concentration. Environ Health Perspect 2008;116:1167\u201371. https:\/\/doi.org\/10.1289\/ehp.11230.","DOI":"10.1289\/ehp.11230"},{"key":"2026070915585965736_j_reveh-2021-0035_ref_024","doi-asserted-by":"crossref","unstructured":"Lim, SS, Vos, T, Flaxman, AD, Danaei, G, Shibuya, K, Adair-Rohani, H, et al.. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990\u20132010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012;380:2224\u201360. https:\/\/doi.org\/10.1016\/S0140-6736(12)61766-8.","DOI":"10.1016\/S0140-6736(12)61766-8"}],"container-title":["Reviews on Environmental Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/reveh-2021-0035\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/reveh-2021-0035\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T15:59:04Z","timestamp":1783612744000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/reveh-2021-0035\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,9]]},"references-count":24,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,6,9]]},"published-print":{"date-parts":[[2022,6,27]]}},"alternative-id":["10.1515\/reveh-2021-0035"],"URL":"https:\/\/doi.org\/10.1515\/reveh-2021-0035","relation":{},"ISSN":["0048-7554","2191-0308"],"issn-type":[{"value":"0048-7554","type":"print"},{"value":"2191-0308","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,9]]}}}