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We review the current literature to summarise what is known about SEGA in the following areas: (1) diagnostic criteria, (2) prevalence, (3) origin, (4) imaging characteristics, (5) growth rate, (6) genotype-phenotype correlation, (7) congenital SEGA and (8) SEGA as a marker of severity of other TSC manifestations.<\/jats:p>","DOI":"10.1515\/revneuro-2017-0027","type":"journal-article","created":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T22:17:14Z","timestamp":1512598634000},"page":"295-301","source":"Crossref","is-referenced-by-count":31,"title":["The natural history of subependymal giant cell astrocytomas in tuberous sclerosis complex: a review"],"prefix":"10.1515","volume":"29","author":[{"given":"Denise L.","family":"Chan","sequence":"first","affiliation":[{"name":"Department of Neurology, Sydney Children\u2019s Hospital , Randwick, NSW 2031 , Australia"},{"name":"School of Women\u2019s and Children\u2019s Health, Faculty of Medicine , University of New South Wales , Sydney, NSW 2000 , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tessa","family":"Calder","sequence":"additional","affiliation":[{"name":"School of Women\u2019s and Children\u2019s Health, Faculty of Medicine , University of New South Wales , Sydney, NSW 2000 , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Lawson","sequence":"additional","affiliation":[{"name":"Department of Neurology, Sydney Children\u2019s Hospital , Randwick, NSW 2031 , Australia"},{"name":"School of Women\u2019s and Children\u2019s Health, Faculty of Medicine , University of New South Wales , Sydney, NSW 2000 , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Mowat","sequence":"additional","affiliation":[{"name":"School of Women\u2019s and Children\u2019s Health, Faculty of Medicine , University of New South Wales , Sydney, NSW 2000 , Australia"},{"name":"Centre for Clinical Genetics, Sydney Children\u2019s Hospital , Randwick, NSW 2031 , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean E.","family":"Kennedy","sequence":"additional","affiliation":[{"name":"Department of Neurology, Sydney Children\u2019s Hospital , Randwick, NSW 2031 , Australia"},{"name":"School of Women\u2019s and Children\u2019s Health, Faculty of Medicine , University of New South Wales , Sydney, NSW 2000 , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2017,12,6]]},"reference":[{"key":"2024080906353654016_j_revneuro-2017-0027_ref_001_w2aab3b7b1b1b6b1ab1b4b1Aa","doi-asserted-by":"crossref","unstructured":"Adriaensen, M.E., Schaefer-Prokop, C.M., Stijnen, T., Duyndam, D.A.C., Zonnenberg, B.A., and Prokop, M. 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