{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T06:45:06Z","timestamp":1775803506605,"version":"3.50.1"},"reference-count":12,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_rir-2026-0001_s_005\">\n                    <jats:title>Background and Objective<\/jats:title>\n                    <jats:p>The prevalence of Spondyloarthritis (SpA) in China is approximately 1%, with ankylosing spondylitis (AS) at 0.25%. However, community-based incidence data remain scarce and are subject to medical reporting bias. This study aimed to investigate the prevalence of SpA and the health status of patients in Wuyuan County, to provide evidence for the national \u201cRural Health Project for Ankylosing Spondylitis\u201d.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_rir-2026-0001_s_006\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A cross-sectional survey was conducted from August to December 2023 using the WHO COPCORD methodology. A multi-stage stratified random cluster sampling method was employed, including 16, 996 residents. A screening questionnaire based on assessment of Spondyloarthritis international society (ASAS) criteria was used, and SpA diagnoses were confirmed by rheumatologists. Data analysis included Poisson distribution sample size estimation, Mann-Whitney\n                      <jats:italic>U<\/jats:italic>\n                      test, and Bootstrap proportion estimation (SPSS v29.0 and R v4.3.2).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_rir-2026-0001_s_007\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The estimated prevalence of SpA among residents of Wuyuan County in 2023 was 0.14%. A total of 24 patients were diagnosed with SpA (16 males and 8 females). Half of these cases were previously undiagnosed and demonstrated a significant diagnostic delay (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.021). Male patients exhibited more severe functional impairment, as indicated by higher bath ankylosing spondylitis functional index (BASFI) scores compared to their female counterparts (3.29\n                      <jats:italic>vs<\/jats:italic>\n                      . 1.44,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_rir-2026-0001_s_008\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Community screening revealed a significant burden of SpA in rural China, underscoring the need to strengthen primary healthcare resource allocation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/rir-2026-0001","type":"journal-article","created":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T13:23:48Z","timestamp":1774877028000},"page":"34-40","source":"Crossref","is-referenced-by-count":0,"title":["Community-based epidemiological study on the prevalence and health status of Spondyloarthritis in residents of Wuyuan County, China, 2023"],"prefix":"10.1515","volume":"7","author":[{"given":"Shichao","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Rheumatology and Immunology, Wuyuan County Maternal and Child Health Hospital , Shangrao , Jiangxi Province , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiuling","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, The Second Affiliated Hospital of Nanchang University , Nanchang , Jiangxi Province , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhijie","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, The Second Affiliated Hospital of Nanchang University , Nanchang , Jiangxi Province , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dunwu","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, The Second Affiliated Hospital of Nanchang University , Nanchang , Jiangxi Province , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanjia","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, Wuyuan County Maternal and Child Health Hospital , Shangrao , Jiangxi Province , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinying","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, Wuyuan County Maternal and Child Health Hospital , Shangrao , Jiangxi Province , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinghong","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, Wuyuan County Maternal and Child Health Hospital , Shangrao , Jiangxi Province , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Libo","family":"Zha","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, Wuyuan County Maternal and Child Health Hospital , Shangrao , Jiangxi Province , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yumin","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, Wuyuan County Maternal and Child Health Hospital , Shangrao , Jiangxi Province , China"},{"name":"Department of Rheumatology and Immunology, The Second Affiliated Hospital of Nanchang University , Nanchang , Jiangxi Province , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Senmiao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Tuochuan Township Health Center, Wuyuan County , Shangrao , Jiangxi Province , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guoliang","family":"Wu","sequence":"additional","affiliation":[{"name":"Taibai Town Health Center, Wuyuan County , Shangrao , Jiangxi Province , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongpei","family":"Wang","sequence":"additional","affiliation":[{"name":"Duanxin Township Health Center, Wuyuan County , Shangrao , Jiangxi Province , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guixing","family":"Dong","sequence":"additional","affiliation":[{"name":"Zhentou Town Health Center, Wuyuan County , Shangrao , Jiangxi Province , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junbo","family":"Zhu","sequence":"additional","affiliation":[{"name":"Qiukou Central Health Center, Wuyuan County , Shangrao , Jiangxi Province , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, The Second Affiliated Hospital of Nanchang University , Nanchang , Jiangxi Province , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0432-3638","authenticated-orcid":false,"given":"Xinwang","family":"Duan","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, The Second Affiliated Hospital of Nanchang University , Nanchang , Jiangxi Province , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7275-2708","authenticated-orcid":false,"given":"Zhirao","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, Wuyuan County Maternal and Child Health Hospital , Shangrao , Jiangxi Province , China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2026,3,30]]},"reference":[{"key":"2026041005450746272_j_rir-2026-0001_ref_001","doi-asserted-by":"crossref","unstructured":"Calabro JJ, Maltz BA. 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Guidelines for the Diagnosis and Treatment of Rheumatic Diseases. 1st ed. Beijing: People's Medical Publishing House, 2022:14-15. [In Chinese]"},{"key":"2026041005450746272_j_rir-2026-0001_ref_008","doi-asserted-by":"crossref","unstructured":"Lee W, Reveille JD, Davis JC Jr, Learch TJ, Ward MM, Weisman MH. Are there gender differences in severity of ankylosing spondylitis? Results from the PSOAS cohort. Ann Rheum Dis. 2007;66:633-638.","DOI":"10.1136\/ard.2006.060293"},{"key":"2026041005450746272_j_rir-2026-0001_ref_009","doi-asserted-by":"crossref","unstructured":"Jovan\u00ed V, Blasco-Blasco M, Ruiz-Cantero MT, Pascual E. Understanding How the Diagnostic Delay of Spondyloarthritis Differs Between Women and Men: A Systematic Review and Meta-analysis. J Rheumatol. 2017;44:174-183.","DOI":"10.3899\/jrheum.160825"},{"key":"2026041005450746272_j_rir-2026-0001_ref_010","doi-asserted-by":"crossref","unstructured":"Yan F, Wu L, Lang J, Huang Z. Bone density and fracture risk factors in ankylosing spondylitis: a meta-analysis. Osteoporos Int. 2024;35:25-40.","DOI":"10.1007\/s00198-023-06925-1"},{"key":"2026041005450746272_j_rir-2026-0001_ref_011","doi-asserted-by":"crossref","unstructured":"Mei J, Hu H, Ding H, et al. Investigating the causal relationship between ankylosing spondylitis and osteoporosis in the European population: a bidirectional Mendelian randomization study. Front Immunol. 2023;14:1163258.","DOI":"10.3389\/fimmu.2023.1163258"},{"key":"2026041005450746272_j_rir-2026-0001_ref_012","unstructured":"Liao WJ, Song FJ, Liu HF. Effects of sulfasalazine combined with moxibustion methods on patients with cold-dampness obstruction type ankylosing spondylitis. Pak J Pharm Sci. 2020;33:1367-1371."}],"container-title":["Rheumatology and Immunology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/rir-2026-0001\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/rir-2026-0001\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T05:45:50Z","timestamp":1775799950000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/rir-2026-0001\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,1]]},"references-count":12,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,3,30]]},"published-print":{"date-parts":[[2026,4,8]]}},"alternative-id":["10.1515\/rir-2026-0001"],"URL":"https:\/\/doi.org\/10.1515\/rir-2026-0001","relation":{},"ISSN":["2719-4523"],"issn-type":[{"value":"2719-4523","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,1]]}}}