{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T23:48:29Z","timestamp":1783554509480,"version":"3.55.0"},"reference-count":29,"publisher":"Walter de Gruyter GmbH","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,4,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_sjpain-2018-0126_s_001\">\n                    <jats:title>Background and aims<\/jats:title>\n                    <jats:p>The relative contribution of patient-related factors and intraoperative nerve damage for the development of chronic pain after surgery is unclear. This study aimed to examine chronic pain after bilateral thoracotomy. We hypothesized, that individual patient-related risk factors would be important resulting in an intraindividual uniformity of pain and hyperphenomena between the two sides of the thorax.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_sjpain-2018-0126_s_002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Twenty patients who had undergone lung transplantation via bilateral thoracotomy 6\u201312 months previously were included from the Danish Lung Transplant program, Rigshospitalet, Denmark, from October 2016 to August 2017. All patients answered questionnaires about pain in and around the scar, completed the Neuropathic Pain Symptom Inventory, and underwent bedside examination for hyperphenomena (brush- and cold-evoked allodynia, pinprick hyperalgesia) and pinprick hypoalgesia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_sjpain-2018-0126_s_003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Nine patients reported spontaneous pain bilaterally, five patients had pain on one side only, and six patients had no pain. Hyperphenomena were present on both sides of the thorax in 13 patients, on one side in four patients, and three patients had no hyperphenomena. The intraindividual uniformity of pain (\n                      <jats:italic>p<\/jats:italic>\n                      =0.029) and hyperphenomena (\n                      <jats:italic>p<\/jats:italic>\n                      =0.011) between the two sides of the thorax suggests that patient-related factors play an important role in the development of chronic pain.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_sjpain-2018-0126_s_004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The results of the present study provide support for the hypothesis of an individual predisposition for the development of chronic pain after thoracotomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_sjpain-2018-0126_s_005\">\n                    <jats:title>Implications<\/jats:title>\n                    <jats:p>Patient-related risk factors contribute to the development of chronic pain after thoracotomy. This result most likely can be transferred to chronic pain after other surgical procedures and therefore help us understand risk factors for chronic pain after surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/sjpain-2018-0126","type":"journal-article","created":{"date-parts":[[2018,12,22]],"date-time":"2018-12-22T07:01:46Z","timestamp":1545462106000},"page":"271-277","source":"Crossref","is-referenced-by-count":7,"title":["Chronic pain after bilateral thoracotomy in lung transplant patients"],"prefix":"10.1515","volume":"19","author":[{"given":"Pernille L.","family":"Petersen","sequence":"first","affiliation":[{"name":"Department of Ambulatory Surgery , Hvidovre Hospital, Copenhagen University Hospital , Ketteg\u00e5rdsalle 30, 2650 Hvidovre , Copenhagen , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pia","family":"Bredahl","sequence":"additional","affiliation":[{"name":"Department of Thoracic Anaesthesiology, Rigshospitalet , Copenhagen University Hospital , Copenhagen , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Perch","sequence":"additional","affiliation":[{"name":"Department of Cardiology , Section for Lung Transplantation, Rigshospitalet, Copenhagen University Hospital , Copenhagen , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian H.","family":"M\u00f8ller","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery , Rigshospitalet, Copenhagen University Hospital , Copenhagen , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanna B.","family":"Finnerup","sequence":"additional","affiliation":[{"name":"Danish Pain Research Center, Department of Clinical Medicine , Aarhus University , Aarhus , Denmark"},{"name":"Department of Neurology , Aarhus University Hospital , Aarhus , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lone","family":"Nikolajsen","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care , Aarhus University Hospital , Aarhus , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2018,12,22]]},"reference":[{"key":"2025120909562283120_j_sjpain-2018-0126_ref_001","doi-asserted-by":"crossref","unstructured":"Macrae WA. 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