{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:31:50Z","timestamp":1782603110052,"version":"3.54.5"},"reference-count":35,"publisher":"Walter de Gruyter GmbH","issue":"4","license":[{"start":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T00:00:00Z","timestamp":1611532800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100010775","name":"East Denmark Health Science Research Forum","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010775","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Danish Medical Association Research Fund"},{"name":"Danish Health Insurance Foundation"},{"name":"Danish Hospital Foundation for Medical Research"},{"name":"Danish Headache Society"},{"name":"Cool Sorption Foundation"},{"DOI":"10.13039\/100004330","name":"GlaxoSmithKline","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004330","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009947","name":"Merck Sharp Dohme","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009947","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Lundbeck Pharma"},{"DOI":"10.13039\/501100013327","name":"H. Lundbeck","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013327","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,10,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_sjpain-2020-0166_s_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Tension-type headache (TTH) is the most prevalent primary headache disorder. We assessed the cross-sectional impact of TTH on health related quality of life (HRQoL) in a general population. We also examined the association of HRQoL scores with headache frequency, disability, medication overuse, poor self-rated health, psychiatric comorbidity, and pain sensitivity in individuals with TTH.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_sjpain-2020-0166_s_002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A sample of 547 subjects completed a headache diagnostic interview, the SF-12 to calculate physical (PCS) and mental (MCS) health component scores, depression (major depression inventory [MDI]) and neuroticism (Eysenck Personality Questionnaire) measures. We defined the following headache diagnosis categories: pure TTH, pure migraine, and coexistent headache (TTH\u00a0+\u00a0migraine). Cases were further classified into chronic (\u226515) or episodic (&lt;15 headache days\/month).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_sjpain-2020-0166_s_003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Using generalized linear models (GLM) adjusted for age, sex and education, both PCS-12 and MCS-12 scores varied in groups distinguished by migraine and TTH status; scores were lower for individuals with coexistent headache (TTH\u00a0+\u00a0migraine; n=83), followed by pure TTH (n=97) and pure migraine (n=43) compared to the no headache group (n=324) (p\u22640.001). In analyses considering chronicity, PCS-12 scores were lower in chronic coexistent headache followed by pure chronic TTH (CTTH), episodic migraine +\/\u2212 episodic TTH (ETTH) and pure ETTH than in the no headache group (p\u22640.001). MCS-12 scores were lower in pure CTTH, followed by chronic coexistent headache, episodic migraine +\/\u2212 ETTH and pure ETTH compared to the no headache group (p\u22640.001). Multiple regression models showed that in TTH, lower PCS-12 scores were associated with age (p=0.04), female sex (p=0.02), and poor self-rated health (p\u22640.001). Lower MCS-12 scores in TTH were associated with depression (p\u22640.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_sjpain-2020-0166_s_004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In a population sample, TTH, and to higher degree CTTH, are associated with decreased HRQoL.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/sjpain-2020-0166","type":"journal-article","created":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T16:53:46Z","timestamp":1612544026000},"page":"778-787","source":"Crossref","is-referenced-by-count":33,"title":["Health-related quality of life in tension-type headache: a population-based study"],"prefix":"10.1515","volume":"21","author":[{"given":"Sait","family":"Ashina","sequence":"first","affiliation":[{"name":"BIDMC Comprehensive Headache Center , Department of Neurology and Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center , Boston , MA , USA"},{"name":"Department of Clinical Medicine , Faculty of Health Sciences , University of Copenhagen , Copenhagen , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawn C.","family":"Buse","sequence":"additional","affiliation":[{"name":"Department of Neurology , Albert Einstein College of Medicine , Bronx , NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakob B.","family":"Bjorner","sequence":"additional","affiliation":[{"name":"Department of Public Health, Section of Social Medicine , University of Copenhagen , Copenhagen , Denmark"},{"name":"QualityMetric , LLC , Johnston , RI , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Bendtsen","sequence":"additional","affiliation":[{"name":"Danish Headache Center, Department of Neurology , University of Copenhagen, Rigshospitalet Glostrup , Glostrup , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann C.","family":"Lyngberg","sequence":"additional","affiliation":[{"name":"Department of Occupational and Social Medicine , Holbaek Hospital, University of Copenhagen , Holbaek , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rigmor H.","family":"Jensen","sequence":"additional","affiliation":[{"name":"Danish Headache Center, Department of Neurology , University of Copenhagen, Rigshospitalet Glostrup , Glostrup , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard B.","family":"Lipton","sequence":"additional","affiliation":[{"name":"Department of Neurology , Albert Einstein College of Medicine , Bronx , NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2021,1,25]]},"reference":[{"key":"2025120910043523496_j_sjpain-2020-0166_ref_001","doi-asserted-by":"crossref","unstructured":"Stovner, LJ, Hagen, K, Jensen, R, Katsarava, Z, Lipton, RB, Scher, AI, et al.. 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