{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T00:28:15Z","timestamp":1793665695918,"version":"4.5.1"},"reference-count":52,"publisher":"Walter de Gruyter GmbH","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_sjpain-2022-0055_s_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Existing equipment for quantitative sensory testing is generally expensive and not easily applicable in\u00a0a\u00a0clinical setting thus simple bed-side devices are warranted. Pressure hyperalgesia is a common finding in patients with\u00a0musculoskeletal pain and an experimental model is delayed-onset muscle soreness (DOMS). DOMS is\u00a0characterised by muscle hyperalgesia and some studies report facilitation of temporal summation of pain. This study aimed to detect DOMS induced muscle hyperalgesia and temporal summation of pain using a newly developed bed-side quantitative sensory testing device to deliver standardised pressure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_sjpain-2022-0055_s_002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Twenty-two healthy participants participated in two sessions with the second session approximately 48\u00a0h after baseline. Pressure pain intensities were assessed from the gastrocnemius muscle with four probes calibrated to apply 2, 4, 6 and 8\u00a0kg, respectively. Temporal summation of pain (10 stimuli delivered at 0.5\u00a0Hz using the 6\u00a0kg probe) intensities were assessed from the same location. DOMS was evoked in the gastrocnemius muscle by an eccentric exercise. Sleepiness and physical activity were measured with the Epworth Sleepiness Scale and the Global Physical Activity Questionnaire to investigate if they were associated with the quantitative sensory testing measures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_sjpain-2022-0055_s_003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Pressure pain intensity was significantly increased 48\u00a0h after induction of DOMS when compared to baseline for all four probes (p&lt;0.05). Temporal summation of pain was not statistically significant affected by DOMS and sleep quality and physical activity did not associate with any of the measures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_sjpain-2022-0055_s_004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study introduces a simple, bed-side assessment tool for the assessment of pressure pain intensity and hence hyperalgesia and temporal summation of pain.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/sjpain-2022-0055","type":"journal-article","created":{"date-parts":[[2022,8,15]],"date-time":"2022-08-15T11:50:22Z","timestamp":1660564222000},"page":"382-388","source":"Crossref","is-referenced-by-count":3,"title":["A simple, bed-side tool to assess evoked pressure pain intensity"],"prefix":"10.1515","volume":"23","author":[{"given":"S\u00f8ren Nicolai Frederiksen","family":"Hostrup","sequence":"first","affiliation":[{"name":"Department of Health Science and Technology, Faculty of Medicine , Aalborg University , Aalborg , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f8ren Francis Dyhrberg","family":"O\u2019Neill","sequence":"additional","affiliation":[{"name":"Spine Centre of Southern Denmark , University Hospital of Southern Denmark , Middelfart , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesper Bie","family":"Larsen","sequence":"additional","affiliation":[{"name":"Department of Health Science and Technology, Faculty of Medicine , Aalborg University , Aalborg , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Arendt-Nielsen","sequence":"additional","affiliation":[{"name":"Center for Neuroplasticity and Pain, SMI, Department of Health Science and Technology, Faculty of Medicine , Aalborg University , Aalborg , Denmark"},{"name":"Department of Medical Gastroenterology, Mech-Sense , Aalborg University Hospital , Aalborg , Denmark"},{"name":"Center for Mathematical Modeling of Knee Osteoarthritis (MathKOA), Department of Material and Production, Faculty of Engineering and Science , Aalborg University , Aalborg , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristian Kj\u00e6r","family":"Petersen","sequence":"additional","affiliation":[{"name":"Center for Neuroplasticity and Pain, SMI, Department of Health Science and Technology, Faculty of Medicine , Aalborg University , Aalborg , Denmark"},{"name":"Center for Mathematical Modeling of Knee Osteoarthritis (MathKOA), Department of Material and Production, Faculty of Engineering and Science , Aalborg University , Aalborg , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2022,8,16]]},"reference":[{"key":"2025120910050080522_j_sjpain-2022-0055_ref_001","doi-asserted-by":"crossref","unstructured":"Gureje, O, Von Korff, M, Simon, GE, Gater, R. Persistent pain and well-being: a World Health Organization study in primary care. JAMA 1998;280:147\u201351. https:\/\/doi.org\/10.1001\/jama.280.2.147.","DOI":"10.1001\/jama.280.2.147"},{"key":"2025120910050080522_j_sjpain-2022-0055_ref_002","doi-asserted-by":"crossref","unstructured":"Breivik, H, Collett, B, Ventafridda, V, Cohen, R, Gallacher, D. Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment. Eur J Pain 2006;10:287\u2013333. https:\/\/doi.org\/10.1016\/j.ejpain.2005.06.009.","DOI":"10.1016\/j.ejpain.2005.06.009"},{"key":"2025120910050080522_j_sjpain-2022-0055_ref_003","doi-asserted-by":"crossref","unstructured":"Dahlhamer, J, Lucas, J, Zelaya, C, Nahin, R, Mackey, S, DeBar, L, et al.. Prevalence of chronic pain and high-impact chronic pain among adults\u00a0\u2014 United States, 2016. Morb Mortal Wkly Rep 2018;67:1001\u20136. https:\/\/doi.org\/10.15585\/mmwr.mm6736a2.","DOI":"10.15585\/mmwr.mm6736a2"},{"key":"2025120910050080522_j_sjpain-2022-0055_ref_004","doi-asserted-by":"crossref","unstructured":"M\u00e4ntyselk\u00e4, P, Kumpusalo, E, Ahonen, R, Kumpusalo, A, Kauhanen, J, Viinam\u00e4ki, H, et al.. Pain as a reason to visit the doctor: a study in finnish primary health care. Pain 2001;89:175\u201380. https:\/\/doi.org\/10.1016\/S0304-3959(00)00361-4.","DOI":"10.1016\/S0304-3959(00)00361-4"},{"key":"2025120910050080522_j_sjpain-2022-0055_ref_005","doi-asserted-by":"crossref","unstructured":"Koleva, D, Krulichova, I, Bertolini, G, Caimi, V, Garattini, L. Pain in primary care: an Italian survey. 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Phys Ther 2015;95:1536\u201346. https:\/\/doi.org\/10.2522\/ptj.20140352.","DOI":"10.2522\/ptj.20140352"},{"key":"2025120910050080522_j_sjpain-2022-0055_ref_021","doi-asserted-by":"crossref","unstructured":"Arendt-Nielsen, L, Morlion, B, Perrot, S, Dahan, A, Dickenson, A, Kress, HG, et al.. Assessment and manifestation of central sensitisation across different chronic pain conditions. Eur J Pain 2018;22:216\u201341. https:\/\/doi.org\/10.1002\/ejp.1140.","DOI":"10.1002\/ejp.1140"},{"key":"2025120910050080522_j_sjpain-2022-0055_ref_022","doi-asserted-by":"crossref","unstructured":"Rathleff, MS, Rathleff, CR, Stephenson, A, Mellor, R, Matthews, M, Crossley, K, et al.. Adults with patellofemoral pain do not exhibit manifestations of peripheral and central sensitization when compared to healthy pain-free age and sex matched controls\u00a0\u2013 an assessor blinded cross-sectional study. 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Sleep 1991;14:540\u20135. https:\/\/doi.org\/10.1093\/sleep\/14.6.540.","DOI":"10.1093\/sleep\/14.6.540"},{"key":"2025120910050080522_j_sjpain-2022-0055_ref_037","doi-asserted-by":"crossref","unstructured":"Armstrong, T, Bull, F. Development of the World Health Organization global physical activity questionnaire (GPAQ). J Public Health 2006;14:66\u201370. https:\/\/doi.org\/10.1007\/s10389-006-0024-x.","DOI":"10.1007\/s10389-006-0024-x"},{"key":"2025120910050080522_j_sjpain-2022-0055_ref_038","doi-asserted-by":"crossref","unstructured":"Cleland, CL, Hunter, RF, Kee, F, Cupples, ME, Sallis, JF, Tully, MA. Validity of the global physical activity questionnaire (GPAQ) in assessing levels and change in moderate-vigorous physical activity and sedentary behaviour. BMC Publ Health 2014;14:1255. https:\/\/doi.org\/10.1186\/1471-2458-14-1255.","DOI":"10.1186\/1471-2458-14-1255"},{"key":"2025120910050080522_j_sjpain-2022-0055_ref_039","doi-asserted-by":"crossref","unstructured":"Laeremans, M, Dons, E, Avila-Palencia, I, Carrasco-Turigas, G, Orjuela, JP, Anaya, E, et al.. Physical activity and sedentary behaviour in daily life: a comparative analysis of the global physical activity questionnaire (GPAQ) and the sensewear armband. PLoS One 2017;12:e0177765. https:\/\/doi.org\/10.1371\/journal.pone.0177765.","DOI":"10.1371\/journal.pone.0177765"},{"key":"2025120910050080522_j_sjpain-2022-0055_ref_040","doi-asserted-by":"crossref","unstructured":"Woolf, CJ. Central sensitization: implications for the diagnosis and treatment of pain. Pain 2011;152(3 Suppl):S2\u201315. https:\/\/doi.org\/10.1016\/j.pain.2010.09.030.","DOI":"10.1016\/j.pain.2010.09.030"},{"key":"2025120910050080522_j_sjpain-2022-0055_ref_041","doi-asserted-by":"crossref","unstructured":"Staud, R, Cannon, RC, Mauderli, AP, Robinson, ME, Price, DD, Vierck, CJ. Temporal summation of pain from mechanical stimulation of muscle tissue in normal controls and subjects with fibromyalgia syndrome. Pain 2003;102:87\u201395. https:\/\/doi.org\/10.1016\/s0304-3959(02)00344-5.","DOI":"10.1016\/s0304-3959(02)00344-5"},{"key":"2025120910050080522_j_sjpain-2022-0055_ref_042","doi-asserted-by":"crossref","unstructured":"Arendt-Nielsen, L, Skou, ST, Nielsen, TA, Petersen, KK. Altered central sensitization and pain modulation in the CNS in chronic joint pain. 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