{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T18:27:23Z","timestamp":1760898443996},"reference-count":0,"publisher":"Walter de Gruyter GmbH","issue":"9-10","license":[{"start":{"date-parts":[[1988,10,1]],"date-time":"1988-10-01T00:00:00Z","timestamp":591667200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1988,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p> Chlorpromazine is a widely used phenothiazine tranquilizer known to alter the shape of normal erythrocytes and their osmotic fragility. In order to understand the nature of the interactions chlorpromazine \u00b7 HCl (CPZ \u00b7 HCl) was made to interact with phospholipid bilayers formed by dimyristoylphosphatidylethanolamine (DMPE) and dimyristoylphosphatidylcholine (DMPC). This study was carried out by X-ray diffraction on crystalline powders of various molar mixtures of CPZ \u00b7 HCl with DMPE and DMPC, with and without water. It was found that CPZ \u00b7 HCl significatively affects the bilayer structure of DMPC in the presence of water, but not that of DMPE.<\/jats:p>","DOI":"10.1515\/znc-1988-9-1018","type":"journal-article","created":{"date-parts":[[2018,8,2]],"date-time":"2018-08-02T17:52:49Z","timestamp":1533232369000},"page":"742-748","source":"Crossref","is-referenced-by-count":10,"title":["X-Ray Studies on Phospholipid Bilayers. VIII. Interactions with Chlorpromazine \u00b7 HCl"],"prefix":"10.1515","volume":"43","author":[{"given":"M.","family":"Suwalsky","sequence":"first","affiliation":[{"name":"Departamento de Qu\u00edmica, Universidad de Concepci\u00f3n, Casilla 3-C, Concepci\u00f3n. Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Gimenez","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica, Universidad de Concepci\u00f3n, Casilla 3-C, Concepci\u00f3n. Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Saenger","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica, Universidad de Concepci\u00f3n, Casilla 3-C, Concepci\u00f3n. Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Neira","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica, Universidad de Concepci\u00f3n, Casilla 3-C, Concepci\u00f3n. Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2014,6,2]]},"container-title":["Zeitschrift f\u00fcr Naturforschung C"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.degruyter.com\/view\/j\/znc.1988.43.issue-9-10\/znc-1988-9-1018\/znc-1988-9-1018.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/znc-1988-9-1018\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/znc-1988-9-1018\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,22]],"date-time":"2021-06-22T14:08:12Z","timestamp":1624370892000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/znc-1988-9-1018\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,10,1]]},"references-count":0,"journal-issue":{"issue":"9-10","published-online":{"date-parts":[[2014,6,2]]},"published-print":{"date-parts":[[1988,10,1]]}},"alternative-id":["10.1515\/znc-1988-9-1018"],"URL":"https:\/\/doi.org\/10.1515\/znc-1988-9-1018","relation":{},"ISSN":["1865-7125","0939-5075"],"issn-type":[{"value":"1865-7125","type":"electronic"},{"value":"0939-5075","type":"print"}],"subject":[],"published":{"date-parts":[[1988,10,1]]}}}