{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T03:44:20Z","timestamp":1791085460700,"version":"4.1.0"},"reference-count":0,"publisher":"Walter de Gruyter GmbH","issue":"11-12","license":[{"start":{"date-parts":[[2002,12,1]],"date-time":"2002-12-01T00:00:00Z","timestamp":1038700800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2002,12,1]]},"abstract":"<jats:p>We studied antioxidant activity of six neuroleptics (chlorpromazine, levomepromazine, promethazine, trifluoperazine and thioridazine) and two antidepressants (imipramine and amitriptyline) in the range of concentration of 10<jats:sup>\u22127<\/jats:sup>\u221210<jats:sup>\u22124<\/jats:sup> \u043c. We applied luminol-dependent chemiluminescence to test the ability of these drugs to scavenge the biologically relevant oxygen-derived species: hydroxyl radical, superoxide radical, hypochlorous acid in vitro. We found that the phenothiazines were powerful scavengers of hydroxyl and superoxide radicals. Chlorprothixene, amitriptyline and imipramine had no scavenge activity to the superoxide radical. All drugs showed a moderate scavenger effect on hypochloric anion.<\/jats:p>","DOI":"10.1515\/znc-2002-11-1220","type":"journal-article","created":{"date-parts":[[2015,2,5]],"date-time":"2015-02-05T13:48:16Z","timestamp":1423144096000},"page":"1066-1071","source":"Crossref","is-referenced-by-count":13,"title":["Effect of Some Psychotropic Drugs on Luminol - Dependent Chemiluminescence Induced by O<sub>2<\/sub>\n                  <sup>\u2013<\/sup>, <sup>\u2022<\/sup>OH, HOCl"],"prefix":"10.1515","volume":"57","author":[{"given":"Vera","family":"Hadjimitova","sequence":"first","affiliation":[{"name":"Department of Medical Physics and Biophysics, Sofia University School of Medicine, Sofia 1431, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trayko","family":"Traykov","sequence":"additional","affiliation":[{"name":"Department of Medical Physics and Biophysics, Sofia University School of Medicine, Sofia 1431, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milka","family":"Mileva","sequence":"additional","affiliation":[{"name":"Department of Medical Physics and Biophysics, Sofia University School of Medicine, Sofia 1431, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Ribarov","sequence":"additional","affiliation":[{"name":"Department of Medical Physics and Biophysics, Sofia University School of Medicine, Sofia 1431, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2014,6,2]]},"container-title":["Zeitschrift f\u00fcr Naturforschung C"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyter.com\/view\/journals\/znc\/57\/11-12\/article-p1066.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/znc-2002-11-1220\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/znc-2002-11-1220\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,23]],"date-time":"2022-08-23T05:39:14Z","timestamp":1661233154000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/znc-2002-11-1220\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,12,1]]},"references-count":0,"journal-issue":{"issue":"11-12","published-online":{"date-parts":[[2014,6,2]]},"published-print":{"date-parts":[[2002,12,1]]}},"alternative-id":["10.1515\/znc-2002-11-1220"],"URL":"https:\/\/doi.org\/10.1515\/znc-2002-11-1220","relation":{},"ISSN":["1865-7125","0939-5075"],"issn-type":[{"value":"1865-7125","type":"electronic"},{"value":"0939-5075","type":"print"}],"subject":[],"published":{"date-parts":[[2002,12,1]]}}}