{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T08:52:59Z","timestamp":1789894379578,"version":"4.0.1"},"reference-count":0,"publisher":"Walter de Gruyter GmbH","issue":"1-2","license":[{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,2,1]]},"abstract":"<jats:p>The antimicrobial compounds against the fish pathogen Photobacterium damselae subsp. piscicida were isolated from Polygonum sachalinense rhizomes. The structures of the antimicrobial compounds 1 and 2 were determined by <jats:sup>1<\/jats:sup>H and <jats:sup>13<\/jats:sup>C NMR, 2D-NMR (COSY, HSQC, HMBC and ROESY) and FAB-MS to be phenylpropanoid glycosides, vanicoside A and B, respectively. Both compounds have feruloyl and p-coumaroyl groups bonded to a sucrose moiety in their structures. Vanicoside A also has an acetyl group in the sucrose moiety. The MIC values for vanicoside A and B against Ph. damselae subsp. piscicida DPp-1 were 32 and 64 \u03bcg\/ml, respectively. The antimicrobial activities of these vanicosides were modest, in contrast to higher activities (MICs at &lt;4 \u03bcg\/ml) of antibiotics, florphenicol, ampicillin and amoxicillin, which have been generally used for treating pasteurellosis. The activities of the vanicosides, however, were higher than those (MICs at 256 \u03bcg\/ml) of ferulic acid and p-coumaric acid. It was suggested that the structure of phenylpropanoids esterified with sucrose was essential for higher antimicrobial activity of vanicosides and also acetylation of sucrose might affect the activity against the bacterium.<\/jats:p>","DOI":"10.1515\/znc-2005-1-208","type":"journal-article","created":{"date-parts":[[2015,2,4]],"date-time":"2015-02-04T13:00:35Z","timestamp":1423054835000},"page":"39-44","source":"Crossref","is-referenced-by-count":14,"title":["Antimicrobial Substances from Rhizomes of the Giant Knotweed Polygonum sachalinense against the Fish Pathogen Photobacterium damselae subsp. piscicida"],"prefix":"10.1515","volume":"60","author":[{"given":"Hironori","family":"Kumagai","sequence":"first","affiliation":[{"name":"Graduate School of Fisheries Sciences, Hokkaido University, Hakodate, Hokkaido 041-8611, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Kawai","sequence":"additional","affiliation":[{"name":"Graduate School of Fisheries Sciences, Hokkaido University, Hakodate, Hokkaido 041-8611, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryo","family":"Sawano","sequence":"additional","affiliation":[{"name":"Daiichi Pharmaceutical Co., Ltd., Chuo-ku, Tokyo 103-8234, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideyuki","family":"Kurihara","sequence":"additional","affiliation":[{"name":"Graduate School of Fisheries Sciences, Hokkaido University, Hakodate, Hokkaido 041-8611, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Yamazaki","sequence":"additional","affiliation":[{"name":"Graduate School of Fisheries Sciences, Hokkaido University, Hakodate, Hokkaido 041-8611, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norio","family":"Inoue","sequence":"additional","affiliation":[{"name":"Graduate School of Fisheries Sciences, Hokkaido University, Hakodate, Hokkaido 041-8611, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2014,6,2]]},"container-title":["Zeitschrift f\u00fcr Naturforschung C"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyter.com\/view\/journals\/znc\/60\/1-2\/article-p39.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/znc-2005-1-208\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/znc-2005-1-208\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,23]],"date-time":"2022-08-23T05:15:17Z","timestamp":1661231717000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/znc-2005-1-208\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2,1]]},"references-count":0,"journal-issue":{"issue":"1-2","published-online":{"date-parts":[[2014,6,2]]},"published-print":{"date-parts":[[2005,2,1]]}},"alternative-id":["10.1515\/znc-2005-1-208"],"URL":"https:\/\/doi.org\/10.1515\/znc-2005-1-208","relation":{},"ISSN":["1865-7125","0939-5075"],"issn-type":[{"value":"1865-7125","type":"electronic"},{"value":"0939-5075","type":"print"}],"subject":[],"published":{"date-parts":[[2005,2,1]]}}}