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Thymol was the most abundant constituent (69.61%) followed by <jats:italic>\u03b3<\/jats:italic>-terpinene (8.38%). The antioxidant activity was evaluated using both diphenylpicrylhydrazyl (DPPH\u02d9) reduction and 2-deoxyribose (2-DR) degradation prevention methods. The oil showed a very potent antioxidant activity with IC<jats:sub>50<\/jats:sub> values of 0.20 \u00b1 0.07 and 4.96 \u00b1 0.39 \u03bcg\/mL for the DPPH\u02d9 and 2-DR methods, respectively. The antimicrobial activity of the oil was assessed using the agar diffusion method, and the in vitro cytotoxicity on five different cancer cells was examined using the MTT assay. The oil revealed promising inhibitory activity against Gram positive bacteria, especially <jats:italic>Bacillus subtilis<\/jats:italic> and <jats:italic>Streptococcus pyogenes<\/jats:italic> with an MIC value of 62.5 \u03bcg\/mL. Additionally, the highest cytotoxic activity was observed against the HL-60 cells with an IC<jats:sub>50<\/jats:sub> of 113.5 \u03bcg\/mL. These results validate some of their traditional uses in food preservation.<\/jats:p>","DOI":"10.1515\/znc-2016-0005","type":"journal-article","created":{"date-parts":[[2016,5,6]],"date-time":"2016-05-06T10:01:38Z","timestamp":1462528898000},"page":"155-163","source":"Crossref","is-referenced-by-count":31,"title":["Chemical composition and biological activity of the essential oil from <i>Thymus lanceolatus<\/i>"],"prefix":"10.1515","volume":"71","author":[{"given":"Abdelmounaim","family":"Khadir","sequence":"first","affiliation":[{"name":"Faculty of Nature and Life, Department of Biology , Earth and Universe Sciences, Aboubekr Belka\u00efd University , 13000 Tlemcen, Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mansour","family":"Sobeh","sequence":"additional","affiliation":[{"name":"Institute of Pharmacy and Molecular Biotechnology , University Heidelberg , 69120 Heidelberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haidy A.","family":"Gad","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, Department of Pharmacognosy , Ain Shams University , Abbassia, 11566-Cairo, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fethi","family":"Benbelaid","sequence":"additional","affiliation":[{"name":"Faculty of Nature and Life, Department of Biology , Earth and Universe Sciences, Aboubekr Belka\u00efd University , 13000 Tlemcen, Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mourad","family":"Bendahou","sequence":"additional","affiliation":[{"name":"Faculty of Nature and Life, Department of Biology , Earth and Universe Sciences, Aboubekr Belka\u00efd University , 13000 Tlemcen, Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herbenya","family":"Peixoto","sequence":"additional","affiliation":[{"name":"Institute of Pharmacy and Molecular Biotechnology , University Heidelberg , 69120 Heidelberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Sporer","sequence":"additional","affiliation":[{"name":"Institute of Pharmacy and Molecular Biotechnology , University Heidelberg , 69120 Heidelberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed L.","family":"Ashour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Wink","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Pharmazie und Molekulare Biotechnologie , Universit\u00e4t Heidelberg , Im Neuenheimer Feld 364, 69120 Heidelberg, Germany, Tel.: +49 6221 54 4880, Fax: +49 6221 54 4884"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2016,5,6]]},"reference":[{"key":"2023040103064570883_j_znc-2016-0005_ref_001_w2aab2b8c40b1b7b1ab2ab1Aa","doi-asserted-by":"crossref","unstructured":"Wink M. 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