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The structures of the isolated compounds were determined based on their spectroscopic data. The crude extract and the isolated compounds were assessed <jats:italic>in\u00a0vitro<\/jats:italic> for their antioxidant, lipoxygenase, butyrylcholinesterase (BChE), urease and glucosidase inhibitory potentials. Compounds <jats:bold>1<\/jats:bold>\u2013<jats:bold>3,<\/jats:bold> and <jats:bold>10<\/jats:bold> displayed activities on all the performed bioassays. All the tested samples showed strong to significant antioxidant activity with compound <jats:bold>1<\/jats:bold> being the most potent (IC<jats:sub>50<\/jats:sub> 39.4\u00a0\u03bcM).<\/jats:p>","DOI":"10.1515\/znc-2022-0204","type":"journal-article","created":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T15:12:54Z","timestamp":1676992374000},"page":"275-283","source":"Crossref","is-referenced-by-count":3,"title":["Crotofoligandrin, a new endoperoxide crotofolane-type diterpenoid from the twigs of <i>Croton oligandrus<\/i> Pierre ex. Hutch (Euphorbiaceae)"],"prefix":"10.1515","volume":"78","author":[{"given":"Vanneck Bedel","family":"Tatsinda Tsapi","sequence":"first","affiliation":[{"name":"Department of Chemistry , Faculty of Science , University of Dschang , P.O. Box 67 , Dschang , Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9311-9945","authenticated-orcid":false,"given":"Yannick St\u00e9phane","family":"Fotsing Fongang","sequence":"additional","affiliation":[{"name":"Department of Chemistry , Higher Teachers\u2019 Training College , The University of Maroua , P.O. Box 55 Maroua , Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0685-5854","authenticated-orcid":false,"given":"Angelbert Fusi","family":"Awantu","sequence":"additional","affiliation":[{"name":"Department of Chemistry , Faculty of Science , The University of Bamenda , Bambili , Bamenda , Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Jules","family":"Kezetas Bankeu","sequence":"additional","affiliation":[{"name":"Department of Chemistry , Faculty of Science , The University of Bamenda , Bambili , Bamenda , Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehreen","family":"Lateef","sequence":"additional","affiliation":[{"name":"Multi-Disciplinary Research Lab , Bahria University, Medical and Dental College , Karachi , Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8284-6250","authenticated-orcid":false,"given":"Jean Rodolphe","family":"Chouna","sequence":"additional","affiliation":[{"name":"Department of Chemistry , Faculty of Science , University of Dschang , P.O. Box 67 , Dschang , Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P\u00e9pin","family":"Nkeng-Efouet-Alango","sequence":"additional","affiliation":[{"name":"Department of Chemistry , Faculty of Science , University of Dschang , P.O. Box 67 , Dschang , Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Shaiq","family":"Ali","sequence":"additional","affiliation":[{"name":"H.E.J.\u00a0Research Institute of Chemistry, International Center for Chemical and Biological Sciences , University of Karachi , 75270 , Karachi , Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno Ndjakou","family":"Lenta","sequence":"additional","affiliation":[{"name":"Department of Chemistry , Higher Teacher Training College , University of Yaound\u00e9 I , P.O. 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