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Twelve recreationally trained men (age, 23.2 \u00b1 5.6 years; body mass, 84.3 \u00b1 9.3 kg; body height, 178.9 \u00b1 4.5 cm; and BMI, 26.3 \u00b1 2.3 kg\u00b7m2) volunteered to participate in this study. All subjects were randomly assigned to four experimental protocols (crossover): (a) aerobic training at 60% of VO2max, (b) aerobic training at 80% of VO2max, (c) a resistance exercise (RE) session with a bi-set protocol, and (d) an RE session with a multiple sets protocol. Blood samples were collected before, immediately after and 24 hours following the experimental protocols. After 24 hours, there was a significant increase in CK for the 80% of VO2max protocol vs. the bi-set RE session (p = 0.016). Immediately after the protocols, we observed a significant increase in LDH among certain groups compared to others, as follows: multiple sets RE session vs. 60% of VO2max, bi-set RE session vs. 60% of VO2max, multiple sets RE session vs. 80% of VO2max, and bi-set RE session vs. 80% of VO2max (p = 0.008, p = 0.013; p = 0.002, p = 0.004, respectively). In conclusion, aerobic exercise performed at 80% of VO2max appears to elevate plasma CK levels more than bi-set RE sessions. However, the bi-set and multiple sets RE sessions appeared to trigger greater levels of blood LDH compared to aerobic protocols performed at 60% and 80% of VO2max.<\/jats:p>","DOI":"10.1515\/hukin-2017-0071","type":"journal-article","created":{"date-parts":[[2017,8,2]],"date-time":"2017-08-02T10:02:07Z","timestamp":1501668127000},"page":"65-72","source":"Crossref","is-referenced-by-count":109,"title":["Creatine Kinase and Lactate Dehydrogenase Responses After Different Resistance and Aerobic Exercise Protocols"],"prefix":"10.1515","volume":"58","author":[{"given":"Gustavo A.","family":"Callegari","sequence":"first","affiliation":[{"name":"Methodist University Center , Program of Academic Master of Bioscience and Rehabilitation , Rio Grande do Sul , Brazil"}]},{"given":"Jefferson S.","family":"Novaes","sequence":"additional","affiliation":[{"name":"Federal University of Rio de Janeiro (UFRJ) , Department of Physical Education , Graduate Program , Rio de Janeiro , RJ, Brazil"}]},{"given":"Gabriel R.","family":"Neto","sequence":"additional","affiliation":[{"name":"Federal University of Rio de Janeiro (UFRJ) , Department of Physical Education , Graduate Program , Rio de Janeiro , RJ, Brazil"},{"name":"Associate Graduate Program in Physical Education UPE\/UFPB , Jo\u00e3o Pessoa , Para\u00edba , Brazil"}]},{"given":"Ingrid","family":"Dias","sequence":"additional","affiliation":[{"name":"Federal University of Rio de Janeiro (UFRJ) , Department of Physical Education , Graduate Program , Rio de Janeiro , RJ, Brazil"},{"name":"Federal University of Rio de Janeiro (UFRJ) , Medical Clinic Postgraduate Program , Rio de Janeiro , Brazil"}]},{"given":"Nuno D.","family":"Garrido","sequence":"additional","affiliation":[{"name":"Research Center in Sports Sciences , Health Sciences and Human Development , Vila Real , Portugal"}]},{"given":"Caroline","family":"Dani","sequence":"additional","affiliation":[{"name":"Methodist University Center , Program of Academic Master of Bioscience and Rehabilitation , Rio Grande do Sul , Brazil"}]}],"member":"374","published-online":{"date-parts":[[2017,8,1]]},"reference":[{"key":"2021040701581303811_j_hukin-2017-0071_ref_001_w2aab3b8d106b1b7b1ab2b1b1Aa","doi-asserted-by":"crossref","unstructured":"Baroni BM, Junior ECPL, De Marchi T, Lopes AL, Salvador M, Vaz MA. 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