{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,19]],"date-time":"2025-04-19T04:51:12Z","timestamp":1745038272484},"reference-count":31,"publisher":"Walter de Gruyter GmbH","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,6,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpem-2018-0053_s_999_w2aab3b7c59b1b6b1aab1c16b1Aa\">\n                  <jats:title>Background:<\/jats:title>\n                  <jats:p>The incidence of pediatric metabolic syndrome (MS) has progressively increased. The incidence of type 1 diabetes mellitus (T1DM) has also increased. Thus, some children and adolescents with T1DM exhibit MS parameters. The aim of the study was to evaluate the presence of MS parameters in female adolescents with T1DM based on their nutritional status.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2018-0053_s_998_w2aab3b7c59b1b6b1aab1c16b2Aa\">\n                  <jats:title>Methods:<\/jats:title>\n                  <jats:p>We evaluated 44 adolescents with T1DM (consecutive non-randomized sample) aged between 14 and 18 years, who were on intensive therapy with insulin. Patients were subdivided according to their body mass index (BMI). Variables evaluated include: age, age at diagnosis, weight, height, BMI, abdominal circumference, blood pressure, glycated hemoglobin (HbA<jats:sub>1c<\/jats:sub>), abdominal and pelvic ultrasound and lipoprotein profile. Gynecological history data were also collected.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2018-0053_s_997_w2aab3b7c59b1b6b1aab1c16b3Aa\">\n                  <jats:title>Results:<\/jats:title>\n                  <jats:p>Lipid profile changes were identified in 32% of overweight or obese girls and in 23% of those with an adequate weight. Hypertension (HT) was observed in 19% of overweight or obese girls and in 14% of those with a BMI\u226585th percentile (Pc). The only statistically significant difference between the groups was the presence of abdominal adiposity. All other features, including the presence of dyslipidemia, HT, abdominal adiposity, non-alcoholic steatohepatitis (NASH) and polycystic ovarian syndrome (PCOS), were present in both groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2018-0053_s_996_w2aab3b7c59b1b6b1aab1c16b4Aa\">\n                  <jats:title>Conclusions:<\/jats:title>\n                  <jats:p>Although being overweight and\/or obese aggravates the risk of cardiovascular disease, MS is already present in many young adolescents with T1DM of normal weight. It is necessary that MS risk factors are routinely evaluated in all diabetic adolescents, including those with an adequate BMI.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpem-2018-0053","type":"journal-article","created":{"date-parts":[[2018,5,11]],"date-time":"2018-05-11T22:16:22Z","timestamp":1526076982000},"page":"631-635","source":"Crossref","is-referenced-by-count":11,"title":["Metabolic risk factors in adolescent girls with type 1 diabetes"],"prefix":"10.1515","volume":"31","author":[{"given":"C\u00edntia","family":"Castro-Correia","sequence":"first","affiliation":[{"name":"Pediatric Endocrinology Unit, Pediatrics Service, S\u00e3o Jo\u00e3o Integrated Pediatric Hospital, Alameda Hernani Monteiro, University of Porto Medical School , Porto , Portugal"}]},{"given":"Rita","family":"Santos-Silva","sequence":"additional","affiliation":[{"name":"Pediatric Endocrinology Unit, Pediatrics Service, S\u00e3o Jo\u00e3o Integrated Pediatric Hospital, Alameda Hernani Monteiro, University of Porto Medical School , Porto , Portugal"}]},{"given":"Marta","family":"Pinheiro","sequence":"additional","affiliation":[{"name":"Pediatric Service, S\u00e3o Jo\u00e3o Integrated Pediatric Hospital, Alameda Hern\u00e2ni Monteiro , Porto , Portugal"}]},{"given":"Carla","family":"Costa","sequence":"additional","affiliation":[{"name":"Pediatric Endocrinology Unit, Pediatrics Service, S\u00e3o Jo\u00e3o Integrated Pediatric Hospital, Alameda Hernani Monteiro, University of Porto Medical School , Porto , Portugal"}]},{"given":"Manuel","family":"Fontoura","sequence":"additional","affiliation":[{"name":"Pediatric Endocrinology Unit, Pediatrics Service, S\u00e3o Jo\u00e3o Integrated Pediatric Hospital, Alameda Hernani Monteiro, University of Porto Medical School , Porto , Portugal"}]}],"member":"374","published-online":{"date-parts":[[2018,5,11]]},"reference":[{"key":"2021021317373800858_j_jpem-2018-0053_ref_001_w2aab3b7c59b1b6b1ab2b1b1Aa","doi-asserted-by":"crossref","unstructured":"Ng M, Fleming T, Robinson M, Thomson B, Graetz N, et al. 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