{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T12:24:13Z","timestamp":1754396653427},"reference-count":38,"publisher":"Walter de Gruyter GmbH","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,5,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2016-0065_s_999_w2aab3b7c57b1b6b1aab1c16b1Aa\">\n                  <jats:title>Objective:<\/jats:title>\n                  <jats:p>To compare longitudinal trends of cardiotocographic (CTG) parameters between small-for-gestational-age (SGA) and normal fetuses, from 24 to 41 weeks of pregnancy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2016-0065_s_998_w2aab3b7c57b1b6b1aab1c16b2Aa\">\n                  <jats:title>Methods:<\/jats:title>\n                  <jats:p>A prospective cohort study was carried out in singleton pregnancies without fetal malformations. At least one CTG was performed in each of the following intervals: 24\u201326 weeks+6 days, 27\u201329 weeks+6 days, 30\u201332 weeks+6 days, 33\u201335 weeks+6 days, 36\u201338 weeks+6 days and \u226539 weeks. Tracings were analyzed using the Omniview-SisPorto<jats:sup>\u00ae<\/jats:sup> 3.6 system. Cases with a normal pregnancy outcome, including a birthweight \u226510<jats:sup>th<\/jats:sup> percentile for gestational age, were compared with two groups of SGA fetuses: with birthweight &lt;10<jats:sup>th<\/jats:sup> percentile (SGA&lt;p10) and &lt;3<jats:sup>rd<\/jats:sup> percentile (SGA&lt;p3; a subgroup of the latter). Generalized linear mixed-effects models were used for analysis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2016-0065_s_997_w2aab3b7c57b1b6b1aab1c16b3Aa\">\n                  <jats:title>Results:<\/jats:title>\n                  <jats:p>A total of 176 fetuses (31 SGA) and 1256 tracings (207 from SGA fetuses) were evaluated. All CTG parameters changed significantly throughout pregnancy in the three groups, with a decreasing baseline and probability of decelerations, and an increasing average long-term variability (LTV), average short-term variability (STV) and accelerations. Baseline showed a more pronounced decrease (steeper slope) in SGA fetuses, being higher in these cases at earlier gestational ages and lower later in pregnancy. Average LTV was significantly lower in SGA&lt;p3 fetuses, but a parallel increase occurred in all groups. There was a considerable inter-fetal variability within each group.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2016-0065_s_996_w2aab3b7c57b1b6b1aab1c16b4Aa\">\n                  <jats:title>Conclusion:<\/jats:title>\n                  <jats:p>A unique characterization of CTG trends throughout gestation in SGA fetuses was provided. A steeper descent of the baseline was reported for the first time. The findings raise the possibility of clinical application of computerized CTG analysis in screening and management of fetal growth restriction.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2016-0065","type":"journal-article","created":{"date-parts":[[2016,8,3]],"date-time":"2016-08-03T08:44:51Z","timestamp":1470213891000},"page":"493-501","source":"Crossref","is-referenced-by-count":12,"title":["Longitudinal changes of cardiotocographic parameters throughout pregnancy: a prospective cohort study comparing small-for-gestational-age and normal fetuses from 24 to 40 weeks"],"prefix":"10.1515","volume":"45","author":[{"given":"C\u00e9lia","family":"Amorim-Costa","sequence":"first","affiliation":[{"name":"Departamento de Ginecologia e Obstetr\u00edcia, Faculdade de Medicina do Porto , Alameda Prof. Hern\u00e2ni Monteiro, 4200-319 Porto , Portugal"},{"name":"Institute for Research and Innovation in Health (Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade \u2013 I3S) and Institute of Biomedical Engineering (Instituto de Engenharia Biom\u00e9dica \u2013 INEB) , University of Porto , Porto , Portugal"},{"name":"Center for Research in Health Technologies and Information Systems (CINTESIS), Medical School , University of Porto , Porto , Portugal"}]},{"given":"A. Rita","family":"Gaio","sequence":"additional","affiliation":[{"name":"Department of Mathematics, Faculty of Sciences , University of Porto , Porto , Portugal"},{"name":"Centre of Mathematics of the University of Porto , Porto , Portugal"}]},{"given":"Diogo","family":"Ayres-de-Campos","sequence":"additional","affiliation":[{"name":"Institute for Research and Innovation in Health (Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade \u2013 I3S) and Institute of Biomedical Engineering (Instituto de Engenharia Biom\u00e9dica \u2013 INEB) , University of Porto , Porto , Portugal"},{"name":"Center for Research in Health Technologies and Information Systems (CINTESIS), Medical School , University of Porto , Porto , Portugal"},{"name":"Department of Obstetrics and Gynecology, Medical School , University of Porto , Porto , Portugal"},{"name":"Department of Obstetrics and Gynecology, S. Jo\u00e3o Hospital , Porto , Portugal"}]},{"given":"Jo\u00e3o","family":"Bernardes","sequence":"additional","affiliation":[{"name":"Institute for Research and Innovation in Health (Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade \u2013 I3S) and Institute of Biomedical Engineering (Instituto de Engenharia Biom\u00e9dica \u2013 INEB) , University of Porto , Porto , Portugal"},{"name":"Center for Research in Health Technologies and Information Systems (CINTESIS), Medical School , University of Porto , Porto , Portugal"},{"name":"Department of Obstetrics and Gynecology, Medical School , University of Porto , Porto , Portugal"},{"name":"Department of Obstetrics and Gynecology, Hospital Pedro Hispano , Matosinhos , Portugal"}]}],"member":"374","published-online":{"date-parts":[[2016,7,30]]},"reference":[{"key":"2023040100110787978_j_jpm-2016-0065_ref_001_w2aab3b7c57b1b6b1ab2b2b1Aa","doi-asserted-by":"crossref","unstructured":"Baschat AA. 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