{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T17:31:52Z","timestamp":1790962312355,"version":"4.1.0"},"reference-count":92,"publisher":"Informa Healthcare","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Expert Opinion on Therapeutic Patents"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1517\/13543776.2013.736965","type":"journal-article","created":{"date-parts":[[2012,11,8]],"date-time":"2012-11-08T14:14:23Z","timestamp":1352384063000},"page":"79-98","source":"Crossref","is-referenced-by-count":49,"title":["Sulfatase inhibitors: a patent review"],"prefix":"10.1517","volume":"23","author":[{"given":"Spencer J","family":"Williams","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3197","published-online":{"date-parts":[[2012,11,8]]},"reference":[{"key":"CIT0001","doi-asserted-by":"crossref","first-page":"5736","DOI":"10.1002\/anie.200300632","volume":"43","author":"Hanson SR","year":"2004","journal-title":"Angew Chem Int Ed"},{"key":"CIT0002","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1002\/(SICI)1521-1878(199806)20:6<505::AID-BIES9>3.0.CO;2-K","volume":"20","author":"von Figura K","year":"1998","journal-title":"Bioessays"},{"key":"CIT0003","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.cbpa.2008.06.018","volume":"12","author":"Bojarova P","year":"2008","journal-title":"Curr Opin Chem Biol"},{"key":"CIT0004","doi-asserted-by":"crossref","first-page":"7631","DOI":"10.1073\/pnas.0510501103","volume":"103","author":"Hagelueken G","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"CIT0005","doi-asserted-by":"crossref","first-page":"3526","DOI":"10.1002\/anie.200300631","volume":"43","author":"Chapman E","year":"2004","journal-title":"Angew Chem Int Ed"},{"key":"CIT0006","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.bmcl.2008.11.059","volume":"19","author":"Bojarova P","year":"2009","journal-title":"Bioorg Med Chem Lett"},{"key":"CIT0007","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/B978-0-444-53630-3.00008-7","volume":"186","author":"Reddy DS","year":"2010","journal-title":"Prog Brain Res"},{"key":"CIT0008","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1038\/nrendo.2010.92","volume":"6","author":"Lin SX","year":"2010","journal-title":"Nat Rev Endocrinol"},{"key":"CIT0009","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.mce.2010.12.035","volume":"340","author":"Woo LWL","year":"2011","journal-title":"Mol Cell Endocrinol"},{"key":"CIT0010","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1093\/annonc\/mdr593","volume":"23","author":"Barrios C","year":"2012","journal-title":"Ann Oncol"},{"key":"CIT0011","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1071\/RD01029","volume":"13","author":"Elger W","year":"2001","journal-title":"Reprod Fertil Dev"},{"key":"CIT0012","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/j.steroids.2011.03.010","volume":"76","author":"Maltais R","year":"2011","journal-title":"Steroids"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1002\/med.20008"},{"key":"CIT0014","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1530\/JOE-11-0266","volume":"212","author":"Purohit A","year":"2012","journal-title":"J Endocrinol"},{"key":"CIT0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1517\/13543776.9.8.1083","volume":"9","author":"Poirier D","year":"1999","journal-title":"Expert Opin Ther Patents"},{"key":"CIT0016","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1517\/13543776.15.11.1541","volume":"15","author":"Horvath A","year":"2005","journal-title":"Expert Opin Ther Patents"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1016\/S0969-2126(97)00185-8"},{"key":"CIT0018","doi-asserted-by":"crossref","first-page":"3654","DOI":"10.1021\/bi9714924","volume":"37","author":"Lukatela G","year":"1998","journal-title":"Biochemistry"},{"key":"CIT0019","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1002\/cbic.200700579","volume":"9","author":"Bojarova P","year":"2008","journal-title":"ChemBioChem"},{"key":"CIT0020","doi-asserted-by":"crossref","first-page":"22989","DOI":"10.1074\/jbc.M211497200","volume":"278","author":"Hernandez-Guzman FG","year":"2003","journal-title":"J Biol Chem"},{"key":"CIT0021","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/S0969-2126(01)00609-8","volume":"9","author":"Boltes I","year":"2001","journal-title":"Structure"},{"key":"CIT0022","doi-asserted-by":"crossref","first-page":"35189","DOI":"10.1074\/jbc.M109.053835","volume":"284","author":"Myette JR","year":"2009","journal-title":"J Biol Chem"},{"key":"CIT0023","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/s11154-007-9052-2","volume":"8","author":"Ghayee H","year":"2007","journal-title":"Rev Endocr Metab Dis"},{"key":"CIT0024","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1210\/er.2003-0030","volume":"25","author":"Payne AH","year":"2004","journal-title":"Endocr Rev"},{"key":"CIT0025","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.mce.2011.06.012","volume":"340","author":"Purohit A","year":"2011","journal-title":"Mol Cell Endocrinol"},{"key":"CIT0026","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1006\/abbi.1998.1073","volume":"363","author":"Lin A","year":"1999","journal-title":"Arch Biochem Biophys"},{"key":"CIT0027","first-page":"377","volume":"59","author":"Utsumi T","year":"1999","journal-title":"Cancer Res"},{"key":"CIT0028","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1093\/humrep\/der079","volume":"26","author":"Colette S","year":"2011","journal-title":"Hum Reprod"},{"key":"CIT0039","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.bbrc.2004.07.108","volume":"322","author":"Chander SK","year":"2004","journal-title":"Biochem Biophys Res Commun"},{"key":"CIT0040","doi-asserted-by":"crossref","first-page":"2435","DOI":"10.1158\/1535-7163.MCT-08-0195","volume":"7","author":"Woo LWL","year":"2008","journal-title":"Mol Cancer Ther"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1021\/jm021124k"},{"key":"CIT0042","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1021\/jm00028a002","volume":"37","author":"Howarth NM","year":"1994","journal-title":"J Med Chem"},{"key":"CIT0043","doi-asserted-by":"crossref","first-page":"11508","DOI":"10.1021\/bi00036a025","volume":"34","author":"Purohit A","year":"1995","journal-title":"Biochemistry"},{"key":"CIT0044","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.bmcl.2003.09.064","volume":"14","author":"Abbate F","year":"2004","journal-title":"Bioorg Med Chem Lett"},{"key":"CIT0045","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/0960-0760(95)00214-6","volume":"55","author":"Elger W","year":"1995","journal-title":"J Steroid Biochem Mol Biol"},{"key":"CIT0051","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s10549-007-9495-x","volume":"106","author":"Ishida H","year":"2007","journal-title":"Breast Cancer Res Treat"},{"key":"CIT0052","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.jsbmb.2007.06.003","volume":"108","author":"Ishida H","year":"2008","journal-title":"J Steroid Biochem Mol Biol"},{"key":"CIT0053","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s10549-006-9404-8","volume":"104","author":"Ishida H","year":"2007","journal-title":"Breast Cancer Res Treat"},{"key":"CIT0055","doi-asserted-by":"crossref","first-page":"2506","DOI":"10.1016\/j.bmc.2012.03.007","volume":"20","author":"Woo LWL","year":"2012","journal-title":"Bioorg Med Chem"},{"key":"CIT0060","doi-asserted-by":"crossref","first-page":"3188","DOI":"10.1021\/jm980717l","volume":"42","author":"Hejaz HA","year":"1999","journal-title":"J Med Chem"},{"key":"CIT0065","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1016\/S0968-0896(03)00042-7","volume":"11","author":"Fischer DS","year":"2003","journal-title":"Bioorg Med Chem"},{"key":"CIT0066","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0960-0760(03)00048-7","volume":"84","author":"Fischer DS","year":"2003","journal-title":"J Steroid Biochem Mol Biol"},{"key":"CIT0067","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s10549-007-9769-3","volume":"111","author":"Foster PA","year":"2008","journal-title":"Breast Cancer Res Treat"},{"key":"CIT0068","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.steroids.2005.12.004","volume":"71","author":"Numazawa M","year":"2006","journal-title":"Steroids"},{"key":"CIT0072","doi-asserted-by":"crossref","first-page":"3075","DOI":"10.1016\/S0960-894X(97)10167-6","volume":"7","author":"Woo LWL","year":"1997","journal-title":"Bioorg Med Chem Lett"},{"key":"CIT0074","doi-asserted-by":"crossref","first-page":"2280","DOI":"10.1021\/jm980677l","volume":"42","author":"Ciobanu LC","year":"1999","journal-title":"J Med Chem"},{"key":"CIT0075","first-page":"6442","volume":"63","author":"Ciobanu LC","year":"2003","journal-title":"Cancer Res"},{"key":"CIT0076","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.1016\/S0960-894X(98)00330-8","volume":"8","author":"Poirier D","year":"1998","journal-title":"Bioorg Med Chem Lett"},{"key":"CIT0079","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.jsbmb.2005.01.005","volume":"94","author":"Leese MP","year":"2005","journal-title":"J Steroid Biochem Mol Biol"},{"key":"CIT0084","doi-asserted-by":"crossref","first-page":"8386","DOI":"10.1016\/j.bmc.2006.09.002","volume":"14","author":"Hanson SR","year":"2006","journal-title":"Bioorg Med Chem"},{"key":"CIT0086","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/S0039-128X(97)00038-X","volume":"62","author":"Chu GH","year":"1997","journal-title":"Steroids"},{"key":"CIT0087","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0960-0760(98)00159-9","volume":"68","author":"Kolli A","year":"1999","journal-title":"J Steroid Biochem Mol Biol"},{"key":"CIT0088","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/S0039-128X(02)00030-2","volume":"67","author":"Selcer KW","year":"2002","journal-title":"Steroids"},{"key":"CIT0089","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1021\/jm950931z","volume":"39","author":"Woo LWL","year":"1996","journal-title":"J Med Chem"},{"key":"CIT0090","first-page":"4950","volume":"56","author":"Purohit A","year":"1996","journal-title":"Cancer Res"},{"key":"CIT0093","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/S1074-5521(00)00023-5","volume":"7","author":"Woo LWL","year":"2000","journal-title":"Chem Biol"},{"key":"CIT0094","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1002\/cmdc.201100288","volume":"6","author":"Woo LWL","year":"2011","journal-title":"ChemMedChem"},{"key":"CIT0095","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1124\/dmd.111.038315","volume":"39","author":"Ventura V","year":"2011","journal-title":"Drug Metab Dispos"},{"key":"CIT0096","doi-asserted-by":"crossref","first-page":"abstract 4097","DOI":"10.1158\/0008-5472.SABCS-09-4097","volume":"69","author":"Coombes R","year":"2009","journal-title":"Cancer Res"},{"key":"CIT0097","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1158\/1078-0432.CCR-05-1996","volume":"12","author":"Stanway SJ","year":"2006","journal-title":"Clin Cancer Res"},{"key":"CIT0099","doi-asserted-by":"crossref","first-page":"4310","DOI":"10.1021\/jm020878w","volume":"45","author":"Nussbaumer P","year":"2002","journal-title":"J Med Chem"},{"key":"CIT0100","doi-asserted-by":"crossref","first-page":"5091","DOI":"10.1021\/jm030926s","volume":"46","author":"Nussbaumer P","year":"2003","journal-title":"J Med Chem"},{"key":"CIT0102","doi-asserted-by":"crossref","first-page":"4313","DOI":"10.1016\/j.bmcl.2003.09.050","volume":"13","author":"Schreiner EP","year":"2003","journal-title":"Bioorg Med Chem Lett"},{"key":"CIT0103","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jsbmb.2004.06.004","volume":"92","author":"Billich A","year":"2004","journal-title":"J Steroid Biochem Mol Biol"},{"key":"CIT0105","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1016\/S0960-894X(02)00171-3","volume":"12","author":"Jutten P","year":"2002","journal-title":"Bioorg Med Chem Lett"},{"key":"CIT0106","doi-asserted-by":"crossref","first-page":"3661","DOI":"10.1021\/jm0611657","volume":"50","author":"Jutten P","year":"2007","journal-title":"J Med Chem"},{"key":"CIT0108","doi-asserted-by":"crossref","first-page":"3673","DOI":"10.1016\/j.bmcl.2003.08.019","volume":"13","author":"Nussbaumer P","year":"2003","journal-title":"Bioorg Med Chem Lett"},{"key":"CIT0109","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1016\/j.bmcl.2004.11.069","volume":"15","author":"Lehr P","year":"2005","journal-title":"Bioorg Med Chem Lett"},{"key":"CIT0110","first-page":"MEDI","volume":"226","author":"Lee W","year":"2003","journal-title":"Abstr Pap Am Chem Soc"},{"key":"CIT0112","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0960-894X(98)00707-0","volume":"9","author":"Chu GH","year":"1999","journal-title":"Bioorg Med Chem Lett"},{"key":"CIT0114","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/s10549-007-9494-y","volume":"106","author":"Rasmussen LM","year":"2007","journal-title":"Breast Cancer Res Treat"},{"key":"CIT0116","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1007\/s00280-010-1430-x","volume":"67","author":"Rausch L","year":"2011","journal-title":"Cancer Chemother Pharmacol"},{"key":"CIT0118","doi-asserted-by":"crossref","first-page":"3193","DOI":"10.1021\/jm034033b","volume":"46","author":"Woo LW","year":"2003","journal-title":"J Med Chem"},{"key":"CIT0122","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.jsbmb.2004.12.028","volume":"94","author":"Wood PM","year":"2005","journal-title":"J Steroid Biochem Mol Biol"},{"key":"CIT0123","doi-asserted-by":"crossref","first-page":"2940","DOI":"10.1039\/b707768h","volume":"5","author":"Jackson T","year":"2007","journal-title":"Org Biomol Chem"},{"key":"CIT0125","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1002\/cmdc.200700266","volume":"3","author":"Jackson T","year":"2008","journal-title":"ChemMedChem"},{"key":"CIT0126","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.1021\/jm901705h","volume":"53","author":"Woo LW","year":"2010","journal-title":"J Med Chem"},{"key":"CIT0130","doi-asserted-by":"crossref","first-page":"3135","DOI":"10.1016\/j.bmcl.2004.04.027","volume":"14","author":"Leese MP","year":"2004","journal-title":"Bioorg Med Chem Lett"},{"key":"CIT0131","doi-asserted-by":"crossref","first-page":"5243","DOI":"10.1021\/jm050066a","volume":"48","author":"Leese MP","year":"2005","journal-title":"J Med Chem"},{"key":"CIT0133","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0960-0760(97)00196-9","volume":"64","author":"Purohit A","year":"1998","journal-title":"J Steroid Biochem Mol Biol"},{"key":"CIT0134","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1002\/(SICI)1097-0215(20000215)85:4<584::AID-IJC22>3.0.CO;2-Q","volume":"85","author":"Purohit A","year":"2000","journal-title":"Int J Cancer"},{"key":"CIT0135","first-page":"5441","volume":"60","author":"MacCarthy-Morrogh L","year":"2000","journal-title":"Cancer Res"},{"key":"CIT0138","doi-asserted-by":"crossref","first-page":"2942","DOI":"10.1021\/jm9018806","volume":"53","author":"Jourdan F","year":"2010","journal-title":"J Med Chem"},{"key":"CIT0140","doi-asserted-by":"crossref","first-page":"7683","DOI":"10.1021\/jm060705x","volume":"49","author":"Leese MP","year":"2006","journal-title":"J Med Chem"},{"key":"CIT0141","first-page":"577","volume":"28","author":"Foster PA","year":"2008","journal-title":"Anticancer Res"},{"key":"CIT0142","first-page":"3751","volume":"29","author":"Foster PA","year":"2009","journal-title":"Anticancer Res"},{"key":"CIT0144","doi-asserted-by":"crossref","first-page":"2907","DOI":"10.1039\/c002558e","volume":"46","author":"Leese MP","year":"2010","journal-title":"Chem Commun"},{"key":"CIT0145","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1021\/ml200232c","volume":"3","author":"Leese MP","year":"2012","journal-title":"ACS Med Chem Lett"},{"key":"CIT0146","doi-asserted-by":"publisher","DOI":"10.1002\/emmm.200900036"},{"key":"CIT0149","first-page":"173","volume":"41","author":"Frobe C","year":"1990","journal-title":"J Soc Cosmet Chem"},{"key":"CIT0152","first-page":"133","volume":"42","author":"Charig A","year":"1991","journal-title":"J Soc Cosmet Chem"},{"key":"CIT0154","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1586\/era.10.201","volume":"11","author":"Palmieri C","year":"2011","journal-title":"Expert Rev Anticancer Ther"}],"container-title":["Expert Opinion on Therapeutic Patents"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/13543776.2013.736965","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T02:27:57Z","timestamp":1498012077000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1517\/13543776.2013.736965"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11,8]]},"references-count":92,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2012,10,25]]},"published-print":{"date-parts":[[2013,1]]}},"alternative-id":["10.1517\/13543776.2013.736965"],"URL":"https:\/\/doi.org\/10.1517\/13543776.2013.736965","relation":{},"ISSN":["1354-3776","1744-7674"],"issn-type":[{"value":"1354-3776","type":"print"},{"value":"1744-7674","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,8]]}}}