{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T17:07:20Z","timestamp":1790096840932,"version":"4.0.1"},"reference-count":32,"publisher":"Informa Healthcare","issue":"1","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Therapeutic Patents"],"published-print":{"date-parts":[[2015,1,2]]},"DOI":"10.1517\/13543776.2014.982532","type":"journal-article","created":{"date-parts":[[2014,11,29]],"date-time":"2014-11-29T05:50:19Z","timestamp":1417240219000},"page":"5-15","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":52,"title":["Sirtuin modulators: an updated patent review (2012 \u2013 2014)"],"prefix":"10.1517","volume":"25","author":[{"given":"Paolo","family":"Mellini","sequence":"first","affiliation":[{"name":"1Sapienza Universit\u00e0 di Roma, Dipartimento di Chimica e Tecnologie del Farmaco, P.le A. Moro 5, 00185 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Valente","sequence":"additional","affiliation":[{"name":"1Sapienza Universit\u00e0 di Roma, Dipartimento di Chimica e Tecnologie del Farmaco, P.le A. Moro 5, 00185 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonello","family":"Mai","sequence":"additional","affiliation":[{"name":"1Sapienza Universit\u00e0 di Roma, Dipartimento di Chimica e Tecnologie del Farmaco, P.le A. Moro 5, 00185 Rome, Italy"},{"name":"2Department of Drug Chemistry and Technologies, Sapienza Universit\u00e0 di Roma, Istituto Pasteur-Fondazione Cenci Bolognetti, P.le A. Moro 5, 00185 Rome, Italy ; ;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3197","published-online":{"date-parts":[[2014,11,29]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1016\/j.ddtec.2012.08.003"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1126\/science.1207861"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1038\/nature12038"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e05-01-0033"},{"key":"CIT0005","first-page":"1399","volume":"6","author":"Yuan H","year":"2013","journal-title":"OncoTargets Ther"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.00822-12"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2013.00048"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2013.05.012"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.10.047"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2012.06762.x"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-08-3365"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2003.08.029"},{"key":"CIT0013","first-page":"15","volume":"1","author":"Park SH","year":"2012","journal-title":"Transl Cancer Res"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2013.10.005"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1177\/1947601913486351"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.11.020"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2012.332"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1038\/nature11043"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M509329200"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1038\/ng1534"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2559"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1002924107"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1126\/science.1143780"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2006.07.004"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2009.07.014"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1007\/s13365-010-0012-3"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1038\/nature06261"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1126\/science.1231097"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1126\/science.1146585"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.088682"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.133892"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1111\/bph.12496"}],"container-title":["Expert Opinion on Therapeutic Patents"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/13543776.2014.982532","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,7,3]],"date-time":"2018-07-03T13:16:46Z","timestamp":1530623806000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1517\/13543776.2014.982532"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,29]]},"references-count":32,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2014,12,12]]},"published-print":{"date-parts":[[2015,1,2]]}},"alternative-id":["10.1517\/13543776.2014.982532"],"URL":"https:\/\/doi.org\/10.1517\/13543776.2014.982532","relation":{},"ISSN":["1354-3776","1744-7674"],"issn-type":[{"value":"1354-3776","type":"print"},{"value":"1744-7674","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,29]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ietp20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ietp20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"}]}}