{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:52:38Z","timestamp":1758477158439},"reference-count":63,"publisher":"Informa Healthcare","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Expert Opinion on Investigational Drugs"],"published-print":{"date-parts":[[2002,3]]},"DOI":"10.1517\/13543784.11.3.431","type":"journal-article","created":{"date-parts":[[2005,5,4]],"date-time":"2005-05-04T20:23:55Z","timestamp":1115238235000},"page":"431-443","source":"Crossref","is-referenced-by-count":20,"title":["Endothelin receptor antagonists in cardiology clinical trials"],"prefix":"10.1517","volume":"11","author":[{"given":"Thomas","family":"Neunteufl","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rudolf","family":"Berger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Pacher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3197","published-online":{"date-parts":[[2005,2,24]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1038\/332411a0"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(90)91198-2"},{"key":"CIT0004","doi-asserted-by":"crossref","first-page":"21394","DOI":"10.1016\/S0021-9258(19)36936-4","volume":"268","author":"TAKAHASHI M","year":"1993","journal-title":"Biol. Chem."},{"key":"CIT0005","doi-asserted-by":"crossref","first-page":"26759","DOI":"10.1016\/S0021-9258(19)74378-6","volume":"268","author":"OHNAKA K","year":"1993","journal-title":"Biol. Chem."},{"key":"CIT0006","doi-asserted-by":"crossref","first-page":"18275","DOI":"10.1016\/S0021-9258(17)32298-6","volume":"269","author":"SHIMADA K","year":"1994","journal-title":"Biol. Chem."},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.92.3.357"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.94.3.316"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.97.8.752"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1172\/JCI114477"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.85.5.1894"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1997.7940"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1681.1990.tb01318.x"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.5.1593"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199706000-00011"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-199601000-00016"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.10.5476"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.94.7.1578"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)91504-4"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.85.4.1374"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.89.4.1580"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(95)00520-X"},{"key":"CIT0030","first-page":"1695","volume":"32","author":"HOLSMANN M","year":"1998","journal-title":"FREY Bet al.: Value of cardiopulmonary exercise testing and big endothelin plasma levels to predict short-term prognosis of patients with chronic heart failure. Am. Coll Cardiol."},{"key":"CIT0032","first-page":"504","volume":"85","author":"CODY RJ","year":"1992","journal-title":"KELLEY R.: Plasma endothelin correlates with the extent of pulmonary hypertension in patients with chronic congestive heart failure. Circulation"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(92)90183-N"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)80783-8"},{"key":"CIT0036","first-page":"27","volume":"2014","author":"Optimism returns to heart failure R","year":"1995","journal-title":"&D: SCRIP World Pharmaceutical News"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.21.2262"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.7.973"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00649-5"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.7.981"},{"key":"CIT0067","first-page":"449","volume":"292","author":"BURRELL KM","year":"2000","journal-title":"J Pharmacol. Exp. Ther."},{"key":"CIT0068","first-page":"1752","volume":"94","author":"BRUNNER F","year":"1996","journal-title":"Role of suppression of endogenous endothelin secretion. Circulation"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1993.1327"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199110033251404"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1097\/00005344-199800001-00027"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.67.5.383"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)90303-6"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.89.4.1573"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.92.11.3312"},{"key":"CIT0086","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/27.9.1613"},{"key":"CIT0087","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.4.646"},{"key":"CIT0089","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(96)88634-2"},{"key":"CIT0090","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.97.25.2551"},{"key":"CIT0092","first-page":"819","volume":"146","author":"KOWALA MC","year":"1995","journal-title":"Pathol"},{"key":"CIT0093","first-page":"294","volume":"8","author":"DAY R","year":"1995","journal-title":"Jim. I Hypertens."},{"key":"CIT0094","first-page":"803","volume":"9","author":"LI JS","year":"1996","journal-title":"Jim. .1 Hypertens."},{"key":"CIT0095","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.30.4.905"},{"key":"CIT0096","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.21.3.294"},{"key":"CIT0097","doi-asserted-by":"publisher","DOI":"10.1038\/368703a0"},{"key":"CIT0098","doi-asserted-by":"publisher","DOI":"10.1006\/jmcc.1996.0117"},{"key":"CIT0099","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.11.2068"},{"key":"CIT0100","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199803193381202"},{"key":"CIT0102","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.100.16.1680"},{"key":"CIT0109","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.97.8.752"},{"key":"CIT0110","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.31.1.499"},{"key":"CIT0111","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.100.1.5"},{"key":"CIT0113","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199701093360207"},{"key":"CIT0115","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199507273330403"},{"key":"CIT0121","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)06250-X"},{"key":"CIT0126","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199207093270203"},{"key":"CIT0127","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.70.4.580"},{"key":"CIT0128","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-121-6-199409150-00003"},{"key":"CIT0129","doi-asserted-by":"publisher","DOI":"10.1007\/s001090050363"}],"container-title":["Expert Opinion on Investigational Drugs"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/13543784.11.3.431","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,10]],"date-time":"2021-07-10T15:21:58Z","timestamp":1625930518000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1517\/13543784.11.3.431"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,3]]},"references-count":63,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2005,2,24]]},"published-print":{"date-parts":[[2002,3]]}},"alternative-id":["10.1517\/13543784.11.3.431"],"URL":"https:\/\/doi.org\/10.1517\/13543784.11.3.431","relation":{},"ISSN":["1354-3784","1744-7658"],"issn-type":[{"value":"1354-3784","type":"print"},{"value":"1744-7658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,3]]}}}