{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T16:24:03Z","timestamp":1791995043393,"version":"4.4.0"},"reference-count":48,"publisher":"Informa Healthcare","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Expert Opinion on Investigational Drugs"],"published-print":{"date-parts":[[2005,7]]},"DOI":"10.1517\/13543784.14.7.893","type":"journal-article","created":{"date-parts":[[2005,7,15]],"date-time":"2005-07-15T17:01:04Z","timestamp":1121446864000},"page":"893-903","source":"Crossref","is-referenced-by-count":41,"title":["Febuxostat: a non-purine, selective inhibitor of xanthine oxidase for the management of hyperuricaemia in patients with gout"],"prefix":"10.1517","volume":"14","author":[{"given":"H Ralph","family":"Schumacher Jr","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3197","published-online":{"date-parts":[[2005,7,15]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1007\/s100670050005"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1991.03470210072035"},{"key":"CIT0003","first-page":"2403","volume":"29","author":"ARROMDEE E","year":"2002","journal-title":"Rheumatol"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-003-0072-y"},{"issue":"1","key":"CIT0005","first-page":"55","volume":"7","author":"POPP JD","year":"1995","journal-title":"Contemporary Int. Med."},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1002\/art.20405"},{"key":"CIT0007","first-page":"179","volume":"55","author":"YU TF","year":"1961","journal-title":"Prevention of recurrent gouty arthritis over a mean period of five years in 208 gouty subjects. Ann. Intern. Med."},{"key":"CIT0008","first-page":"1950","volume":"29","author":"URANO W","year":"2002","journal-title":"J. Rheumatol"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.2188\/jea.10.403"},{"key":"CIT0010","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1093\/oxfordjournals.aje.a117634","volume":"142","author":"LEE J","year":"1995","journal-title":"Am. J. EpidemioL"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1097\/01.rhu.0000129082.42094.fc"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-004-0074-4"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.324.7352.1488"},{"issue":"4","key":"CIT0014","first-page":"261","volume":"10","author":"LI E","year":"2004","journal-title":"Hong Kong Med. J."},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1016\/S0149-2918(04)90035-5"},{"key":"CIT0016","first-page":"331","volume":"29","author":"SCHLESINGER N","year":"2002","journal-title":"Rheumatol"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1097\/00002281-199909000-00020"},{"key":"CIT0018","first-page":"577","volume":"28","author":"LI-YU J","year":"2001","journal-title":"Can we determine when urate stores are depleted enough to prevent attacks of gout? Rheumatol"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780341203"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-002-0658-1"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keg103"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1136\/ard.62.6.572"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1007\/BF01492986"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1136\/ard.40.3.245"},{"key":"CIT0026","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1177\/106002809302700317","volume":"27","author":"ARELLANO F","year":"1993","journal-title":"Ann. Pharmacother."},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.22.810"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(00)00532-4"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(81)80035-7"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1007\/BF01968126"},{"issue":"1","key":"CIT0033","first-page":"56","volume":"19","author":"MASSON E","year":"1996","journal-title":"Leukaemia"},{"issue":"9","key":"CIT0034","first-page":"1036","volume":"227","author":"ANON","year":"1974","journal-title":"Interaction in relation to bone marrow depression. Boston Collaborative Drug Surveillance Program. JAMA"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(74)91797-8"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M208307200"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(93)90033-E"},{"key":"CIT0038","first-page":"307","volume":"104","author":"HORIUCHI H","year":"1999","journal-title":"Res. Comm. Mol. PathoL Pharmacol."},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(93)90201-R"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2004.10.031"},{"key":"CIT0042","first-page":"2876","volume":"243","author":"KRENITSKY TA","year":"1968","journal-title":"Studies with intact erythrocytes and the purified enzyme. Biol. Chem."},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(77)90171-X"},{"key":"CIT0044","first-page":"3801","volume":"248","author":"FYFE JA","year":"1973","journal-title":"Effects of some allopurinol metaboliteis on the enzyme. J. Biol. Chem."},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1159\/000028344"},{"issue":"3","key":"CIT0046","first-page":"292","volume":"104","author":"HORIUCHI H","year":"1999","journal-title":"Res. Commun. MoL PathoL Pharmacol."},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1081\/NCN-200027372"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1097\/00045391-200501000-00005"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1081\/NCN-200027377"},{"issue":"2","key":"CIT0057","first-page":"P50","volume":"77","author":"KHOSRAVAN R","year":"2005","journal-title":"Clin. Pharmacol Ther."},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1002\/art.20935"},{"issue":"10","key":"CIT0072","first-page":"1195","volume":"44","author":"YU P","year":"2004","journal-title":"J. Clin. Pharmacol"}],"container-title":["Expert Opinion on Investigational Drugs"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/13543784.14.7.893","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,3,6]],"date-time":"2019-03-06T20:40:14Z","timestamp":1551904814000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1517\/13543784.14.7.893"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,7]]},"references-count":48,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2005,7,15]]},"published-print":{"date-parts":[[2005,7]]}},"alternative-id":["10.1517\/13543784.14.7.893"],"URL":"https:\/\/doi.org\/10.1517\/13543784.14.7.893","relation":{},"ISSN":["1354-3784","1744-7658"],"issn-type":[{"value":"1354-3784","type":"print"},{"value":"1744-7658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,7]]}}}