{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T21:56:21Z","timestamp":1789854981432,"version":"4.0.1"},"reference-count":82,"publisher":"Informa Healthcare","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Expert Opinion on Investigational Drugs"],"published-print":{"date-parts":[[2008,5]]},"DOI":"10.1517\/13543784.17.5.795","type":"journal-article","created":{"date-parts":[[2008,4,30]],"date-time":"2008-04-30T12:18:08Z","timestamp":1209557888000},"page":"795-804","source":"Crossref","is-referenced-by-count":29,"title":["Betahistine: what's new on the agenda?"],"prefix":"10.1517","volume":"17","author":[{"given":"Nir","family":"Barak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3197","published-online":{"date-parts":[[2008,4,30]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1002\/cber.190503803156"},{"key":"CIT0002","first-page":"299","volume":"75","author":"Hunt","year":"1942","journal-title":"J Pharmacol Exp Ther"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1021\/ja01855a077"},{"key":"CIT0004","first-page":"692","volume":"37","author":"Horton","year":"1962","journal-title":"Proc Staff Meet Mayo Clin"},{"key":"CIT0005","first-page":"713","volume":"37","author":"Horton","year":"1962","journal-title":"Proc Staff Meet Mayo Clin"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1966.03100150133043"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0706440"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.16.7.967"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.15.11.1443"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1006\/phrs.2000.0795"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.2165\/00023210-200115110-00004"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(85)90115-3"},{"key":"CIT0013","first-page":"365","volume":"97","author":"Snow","year":"1973","journal-title":"Acat Otolaryngol"},{"key":"CIT0014","first-page":"299","volume":"75","author":"Hunt","year":"1942","journal-title":"J Pharmacol Exp Ther"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.7.3.257"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-145-37893"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1972.tb06881.x"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.3109\/00016489709124020"},{"key":"CIT0019","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1152\/physrev.1991.71.1.1","volume":"71","author":"Schwartz","year":"1991","journal-title":"Physiol Rev"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1034"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0082(00)00039-3"},{"key":"CIT0022","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.1038\/sj.bjp.0706943","volume":"150","author":"Alexander","year":"2007","journal-title":"Br J Pharmacol"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(90)91240-H"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2003.10.061"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(97)00010-9"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1038\/302832a0"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(93)90191-H"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.15.11.1443"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1080\/000164800750044407"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1007\/s10194-006-0296-0"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1961.hed0103007.x"},{"key":"CIT0032","first-page":"178","volume":"10","author":"Horton","year":"1961","journal-title":"Md State Med J"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-939925"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1097\/00019052-200402000-00004"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1968.03140130034007"},{"key":"CIT0036","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1258\/0022215053419871","volume":"119","author":"Smith","year":"2005","journal-title":"J Laryngol Otol"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-200629110-00004"},{"key":"CIT0038","first-page":"CD001873","volume":"1","author":"James","year":"2001","journal-title":"Cochrane Database Syst Rev"},{"key":"CIT0039","first-page":"122","volume":"10","author":"Esser","year":"1968","journal-title":"Curr Ther Res Clin Exp"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1002\/j.1552-4604.1974.tb02314.x"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1974.tb05408.x"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/6.3.179"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.6.2.116"},{"key":"CIT0044","first-page":"612","volume":"3","author":"Hagler","year":"1971","journal-title":"Ann Ophthalmol"},{"key":"CIT0045","first-page":"679","volume":"55","author":"Bugajski","year":"2004","journal-title":"J Physiol Pharmacol"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(98)00186-3"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2004.10.003"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-4328(01)00225-X"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(01)01138-9"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.53.9.2250"},{"key":"CIT0051","first-page":"288","volume":"206","author":"Clineschmidt","year":"1973","journal-title":"Arch Int Pharmacodyn Ther"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9384(88)90142-4"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1016\/0091-3057(88)90315-2"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1016\/0091-3057(85)90061-9"},{"key":"CIT0055","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1093\/jn\/127.8.1519","volume":"127","author":"Vaziri","year":"1997","journal-title":"J Nutr"},{"key":"CIT0056","first-page":"47","volume":"17","author":"Lecklin","year":"1995","journal-title":"Methods Find Exp Clin Pharmacol"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-3057(97)00465-6"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(94)90160-0"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(90)90373-J"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9384(92)90132-L"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(93)90960-U"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1159\/000095339"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.53.9.2250"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9384(98)00321-7"},{"key":"CIT0065","first-page":"701","volume":"53","author":"Szelag","year":"1999","journal-title":"Polish J Pharmacol"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v65n0219"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.55.2.151"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v58n1008c"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1097\/01.jcp.0000177549.36585.29"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1300027"},{"key":"CIT0073","first-page":"13","volume":"65","author":"Wirshing","year":"2004","journal-title":"J Clin Psychiatr"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0611417104"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.162.5.954"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1819.2005.01424.x"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2004.03.005"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1097\/00004850-200503000-00007"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.159.6.1058"},{"key":"CIT0080","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2003.10.004"},{"key":"CIT0081","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.160.2.297"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.1124\/mi.6.2.5"},{"key":"CIT0083","doi-asserted-by":"publisher","DOI":"10.1254\/jphs.FMJ06001X4"},{"key":"CIT0084","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.4.6.1083"}],"container-title":["Expert Opinion on Investigational Drugs"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/13543784.17.5.795","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,9]],"date-time":"2021-09-09T05:55:45Z","timestamp":1631166945000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1517\/13543784.17.5.795"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4,30]]},"references-count":82,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2008,4,30]]},"published-print":{"date-parts":[[2008,5]]}},"alternative-id":["10.1517\/13543784.17.5.795"],"URL":"https:\/\/doi.org\/10.1517\/13543784.17.5.795","relation":{},"ISSN":["1354-3784","1744-7658"],"issn-type":[{"value":"1354-3784","type":"print"},{"value":"1744-7658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,4,30]]}}}