{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T04:16:00Z","timestamp":1754108160437},"reference-count":98,"publisher":"Informa Healthcare","issue":"7","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Investigational Drugs"],"published-print":{"date-parts":[[2015,7,3]]},"DOI":"10.1517\/13543784.2015.1041586","type":"journal-article","created":{"date-parts":[[2015,5,4]],"date-time":"2015-05-04T09:30:52Z","timestamp":1430731852000},"page":"965-979","update-policy":"http:\/\/dx.doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":19,"title":["Romidepsin for the treatment of non-Hodgkin\u2019s lymphoma"],"prefix":"10.1517","volume":"24","author":[{"given":"Victor Y","family":"Yazbeck","sequence":"first","affiliation":[{"name":"1Virginia Commonwealth University, Massey Cancer Center, Richmond, VA, USA"},{"name":"2Virginia Commonwealth University, Department of Internal Medicine, Richmond, VA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Grant","sequence":"additional","affiliation":[{"name":"1Virginia Commonwealth University, Massey Cancer Center, Richmond, VA, USA"},{"name":"2Virginia Commonwealth University, Department of Internal Medicine, Richmond, VA, USA"},{"name":"3Virginia Commonwealth University, Department of Microbiology and Immunology, Richmond, VA, USA"},{"name":"4Virginia Commonwealth University, Department of Biochemistry and Molecular Biology, Richmond, VA, USA"},{"name":"5Virginia Commonwealth University, Department of Human and Molecular Genetics, Richmond, VA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3197","published-online":{"date-parts":[[2015,5,4]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2133"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1038\/nature10351"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1038\/ng1531"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2014.04.004"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20070779"},{"key":"CIT0006","doi-asserted-by":"crossref","first-page":"9","DOI":"10.4137\/GEG.S12270","volume":"6","author":"Heerboth S","year":"2014","journal-title":"Genet Epigenet"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2004.02406.x"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0500369102"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-08-2675"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1008522107"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0408732102"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-08-0385"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(04)00094-2"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1038\/nature09803"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0503221102"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-12-257261"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2010.10.022"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1202059"},{"issue":"11","key":"CIT0019","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1096\/fj.02-1003fje","volume":"17","author":"Warrener R","year":"2003","journal-title":"FASEB J"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-12-257261"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-2114"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1038\/ng1773"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-10-116319"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-03-143644"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-07-6091"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-08-449140"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.20045"},{"issue":"27","key":"CIT0028","doi-asserted-by":"crossref","first-page":"abstract 268","DOI":"10.1200\/jco.2011.29.27_suppl.268","volume":"29","author":"Yardley DA","year":"2011","journal-title":"J Clin Oncol"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2011.08591.x"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2010.08319.x"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-14-0384"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-06-0562"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-14-0805"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-12-2926"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-10-2876"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-2961"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-04-016055"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(14)70440-1"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-03-339879"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-12-0902"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2014.296"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-12-2799"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2013.12.012"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.4161\/auto.6.7.13117"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-03-564534"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1716"},{"issue":"23","key":"CIT0048","first-page":"8420","volume":"63","author":"Rahmani M","year":"2003","journal-title":"Cancer Res"},{"issue":"9","key":"CIT0049","first-page":"2118","volume":"63","author":"Yu C","year":"2003","journal-title":"Cancer Res"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-2430"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-0835"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-10-116376"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-2259"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2227"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.47.315"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1006\/excr.1998.4027"},{"issue":"17","key":"CIT0057","first-page":"4916","volume":"62","author":"Furumai R","year":"2002","journal-title":"Cancer Res"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-07-2256"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.2217\/epi.12.52"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-2952(03)00411-8"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-2952(02)01261-3"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djh271"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-09-1937"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-1934"},{"issue":"21","key":"CIT0065","doi-asserted-by":"crossref","DOI":"10.1182\/blood.V124.21.3050.3050","volume":"124","author":"Holkova B","year":"2014","journal-title":"Blood"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2004.04882.x"},{"key":"CIT0068","author":"Jain S","year":"2015","journal-title":"Clin Cancer Res"},{"issue":"21","key":"CIT0069","volume":"124","author":"Cosenza M","year":"2014","journal-title":"Blood"},{"issue":"21","key":"CIT0070","doi-asserted-by":"crossref","DOI":"10.1182\/blood.V124.21.4493.4493","volume":"124","author":"Zullo K","year":"2014","journal-title":"Blood"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2009.07954.x"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.2011.594437"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1046\/j.1359-4117.2002.01039.x"},{"issue":"3","key":"CIT0074","first-page":"718","volume":"8","author":"Sandor V","year":"2002","journal-title":"Clin Cancer Res"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-13-0109"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-13-0095"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-08-1007"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25584"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdp270"},{"key":"CIT0080","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e3181ec1713"},{"key":"CIT0081","doi-asserted-by":"publisher","DOI":"10.3816\/CGC.2006.n.018"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.1007\/s10637-008-9190-8"},{"key":"CIT0083","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V98.9.2865"},{"key":"CIT0084","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.21.6150"},{"key":"CIT0085","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-10-312603"},{"key":"CIT0086","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.28.9066"},{"key":"CIT0087","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.37.4223"},{"key":"CIT0088","doi-asserted-by":"publisher","DOI":"10.1186\/1756-8722-7-11"},{"issue":"21","key":"CIT0089","doi-asserted-by":"crossref","DOI":"10.1182\/blood.V124.21.1744.1744","volume":"124","author":"Fanale MA","year":"2014","journal-title":"Blood"},{"key":"CIT0090","doi-asserted-by":"crossref","DOI":"10.1200\/jco.2014.32.15_suppl.8582","volume":"32","author":"Lunning MA","year":"2014","journal-title":"JCO"},{"issue":"21","key":"CIT0091","volume":"124","author":"Dai Chihara MP","year":"2014","journal-title":"Blood"},{"issue":"21","key":"CIT0092","volume":"124","author":"Jehan Dupuis M","year":"2014","journal-title":"Blood"},{"key":"CIT0093","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.01.029"},{"key":"CIT0094","doi-asserted-by":"publisher","DOI":"10.1006\/excr.2000.5080"},{"key":"CIT0095","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1210610"},{"key":"CIT0096","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-62703-408-1"},{"key":"CIT0097","doi-asserted-by":"publisher","DOI":"10.1615\/CritRevOncog.2014012378"},{"key":"CIT0098","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-14-0220"},{"issue":"13","key":"CIT0099","first-page":"3637","volume":"63","author":"Rosato RR","year":"2003","journal-title":"Cancer Res"},{"key":"CIT0100","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-07-2140"}],"container-title":["Expert Opinion on Investigational Drugs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/13543784.2015.1041586","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T19:27:22Z","timestamp":1598988442000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1517\/13543784.2015.1041586"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,4]]},"references-count":98,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2015,6,22]]},"published-print":{"date-parts":[[2015,7,3]]}},"alternative-id":["10.1517\/13543784.2015.1041586"],"URL":"https:\/\/doi.org\/10.1517\/13543784.2015.1041586","relation":{},"ISSN":["1354-3784","1744-7658"],"issn-type":[{"value":"1354-3784","type":"print"},{"value":"1744-7658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,4]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieid20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieid20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"}]}}