{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,7]],"date-time":"2024-07-07T07:28:27Z","timestamp":1720337307945},"reference-count":148,"publisher":"Informa UK Limited","issue":"7","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Investigational Drugs"],"published-print":{"date-parts":[[2015,7,3]]},"DOI":"10.1517\/13543784.2015.1041587","type":"journal-article","created":{"date-parts":[[2015,4,29]],"date-time":"2015-04-29T05:45:09Z","timestamp":1430286309000},"page":"851-865","update-policy":"http:\/\/dx.doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":5,"title":["An overview of investigational toxin-directed therapies for the adjunctive management of<i>Bacillus anthracis<\/i>infection and sepsis"],"prefix":"10.1517","volume":"24","author":[{"given":"Lernik","family":"Ohanjanian","sequence":"first","affiliation":[{"name":"National Institutes of Health, Clinical Center, Critical Care Medicine Department, Building 10, Room 2C145, Bethesda, MD 20892, USA ; ;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth E","family":"Remy","sequence":"additional","affiliation":[{"name":"National Institutes of Health, Clinical Center, Critical Care Medicine Department, Building 10, Room 2C145, Bethesda, MD 20892, USA ; ;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Li","sequence":"additional","affiliation":[{"name":"National Institutes of Health, Clinical Center, Critical Care Medicine Department, Building 10, Room 2C145, Bethesda, MD 20892, USA ; ;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xizhong","family":"Cui","sequence":"additional","affiliation":[{"name":"National Institutes of Health, Clinical Center, Critical Care Medicine Department, Building 10, Room 2C145, Bethesda, MD 20892, USA ; ;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter Q","family":"Eichacker","sequence":"additional","affiliation":[{"name":"National Institutes of Health, Clinical Center, Critical Care Medicine Department, Building 10, Room 2C145, Bethesda, MD 20892, USA ; ;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2015,4,28]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-11-217"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201102-0209CI"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-012-2541-0"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.3201\/eid2009.131481"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.3201\/eid0706.010604"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1086\/512372"},{"issue":"51","key":"CIT0007","doi-asserted-by":"crossref","first-page":"pii: 19076","DOI":"10.2807\/ese.13.51.19076-en","volume":"13","author":"Anaraki S","year":"2008","journal-title":"Euro Surveill"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcpc1003887"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES2014.19.32.20877"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.3201\/eid2002.130245"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200608-1239CP"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000000026"},{"issue":"21","key":"CIT0013","first-page":"2063","volume":"369","author":"Angus DC","year":"2013","journal-title":"N Engl J Med"},{"key":"CIT0014","first-page":"4009","volume":"13","author":"Goldman DL","year":"2008","journal-title":"Front Biosci"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.2741\/3382"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.3390\/toxins3091185"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2014.02.012"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biochem.75.103004.142728"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.3390\/toxins2051038"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2011.12.005"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1016\/j.mam.2009.06.001"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01128.2010"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00433.2010"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2011.08.016"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00185.2013"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1517\/17460441.2014.877884"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1021\/jm901024b"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1016\/j.mam.2009.08.007"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1010145107"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis017"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2011.07614.x"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1016\/j.mam.2009.06.003"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1002\/pro.752"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.2174\/1568026614666140929120231"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1111\/2049-632X.12176"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0106393"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00458-13"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.3201\/eid2002.130687"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0810603"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.3390\/toxins5010120"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.04606-14"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jir834"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.73.2.795-802.2005"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.04593-14"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00261-07"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1086\/500148"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3182120691"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.3390\/ijms151018496"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2004.12.005"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01294-08"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0020646"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00592-10"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1007\/s10930-008-9137-0"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0034611"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0509870103"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0039911"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1177\/1087057113478655"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01412-05"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.538587"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2012.03.002"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1086\/653495"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.1.602-605.2004"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M400484200"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2004.07.012"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M703847200"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2010.02.013"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.73.8.5101-5105.2005"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0b013e3181e83204"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.9.3875-3882.2005"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1021\/jm300804e"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1186\/1476-8518-2-5"},{"issue":"4","key":"CIT0073","doi-asserted-by":"crossref","first-page":"105","DOI":"10.3233\/HAB-2004-13402","volume":"13","author":"Wang F","year":"2004","journal-title":"Hum Antibodies"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00352-07"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.74.2.1016-1024.2006"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00460-13"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00712-06"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.05059-11"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.3390\/toxins3111433"},{"key":"CIT0080","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-0285.2011.01285.x"},{"key":"CIT0081","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2006.11.011"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2007.11.001"},{"key":"CIT0083","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1001-958"},{"key":"CIT0084","doi-asserted-by":"publisher","DOI":"10.1021\/mp050040f"},{"key":"CIT0085","doi-asserted-by":"publisher","DOI":"10.1021\/bm060210p"},{"key":"CIT0086","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200604317"},{"key":"CIT0087","doi-asserted-by":"publisher","DOI":"10.1002\/pola.23031"},{"key":"CIT0088","doi-asserted-by":"publisher","DOI":"10.1021\/bm101396u"},{"issue":"6","key":"CIT0089","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1128\/IAI.58.6.1606-1613.1990","volume":"58","author":"Little SF","year":"1990","journal-title":"Infect Immun"},{"issue":"4","key":"CIT0090","doi-asserted-by":"crossref","first-page":"129","DOI":"10.3233\/HAB-2003-12404","volume":"12","author":"Zhao P","year":"2003","journal-title":"Hum Antibodies"},{"key":"CIT0091","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00749-09"},{"key":"CIT0092","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.73.10.6547-6551.2005"},{"key":"CIT0093","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01528-06"},{"key":"CIT0094","doi-asserted-by":"publisher","DOI":"10.1016\/j.imbio.2010.12.001"},{"key":"CIT0095","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/475809"},{"key":"CIT0097","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1994.1281"},{"key":"CIT0098","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2011.05.024"},{"key":"CIT0099","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.05314-11"},{"key":"CIT0100","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0006351"},{"key":"CIT0101","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.400473"},{"key":"CIT0102","doi-asserted-by":"publisher","DOI":"10.1126\/science.109563"},{"key":"CIT0103","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M010222200"},{"key":"CIT0104","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00264-09"},{"key":"CIT0105","doi-asserted-by":"publisher","DOI":"10.1007\/s12010-012-9858-6"},{"issue":"16","key":"CIT0106","doi-asserted-by":"crossref","first-page":"7123","DOI":"10.1016\/S0021-9258(17)38364-3","volume":"261","author":"Friedlander AM","year":"1986","journal-title":"J Biol Chem"},{"key":"CIT0107","doi-asserted-by":"publisher","DOI":"10.1086\/424853"},{"key":"CIT0108","doi-asserted-by":"publisher","DOI":"10.1086\/507311"},{"key":"CIT0109","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.3700505"},{"key":"CIT0110","doi-asserted-by":"publisher","DOI":"10.1529\/biophysj.104.050336"},{"key":"CIT0111","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0066099"},{"key":"CIT0112","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01184-06"},{"key":"CIT0113","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2009.05.054"},{"key":"CIT0114","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2013.08.007"},{"key":"CIT0115","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2005.07.054"},{"key":"CIT0116","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00983-06"},{"key":"CIT0117","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0507488102"},{"key":"CIT0118","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00693-06"},{"key":"CIT0119","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00009-08"},{"key":"CIT0120","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2009.03.053"},{"key":"CIT0121","doi-asserted-by":"publisher","DOI":"10.2174\/138955708783744083"},{"key":"CIT0122","doi-asserted-by":"publisher","DOI":"10.2174\/138920108783497604"},{"key":"CIT0123","doi-asserted-by":"publisher","DOI":"10.1016\/j.mam.2009.07.006"},{"key":"CIT0124","doi-asserted-by":"publisher","DOI":"10.1038\/418386a"},{"key":"CIT0125","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb708"},{"key":"CIT0126","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2005.10.088"},{"key":"CIT0127","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0502159102"},{"key":"CIT0128","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2012.01.095"},{"key":"CIT0129","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2011.02.010"},{"key":"CIT0130","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2010.08.058"},{"key":"CIT0131","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00941-13"},{"key":"CIT0132","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0502733102"},{"key":"CIT0133","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0500508102"},{"key":"CIT0134","doi-asserted-by":"publisher","DOI":"10.1038\/sj.embor.7400118"},{"issue":"2","key":"CIT0135","first-page":"332","volume":"10","author":"Wickliffe KE","year":"2008","journal-title":"Cell Microbiol"},{"key":"CIT0136","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0906581106"},{"key":"CIT0137","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01101-09"},{"key":"CIT0138","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2013.07.002"},{"key":"CIT0139","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0306552101"},{"key":"CIT0140","doi-asserted-by":"publisher","DOI":"10.1016\/j.mam.2009.06.001"},{"key":"CIT0141","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2004.05.020"},{"key":"CIT0142","doi-asserted-by":"publisher","DOI":"10.3390\/toxins4111288"},{"key":"CIT0143","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2008.06.036"},{"key":"CIT0144","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2009.04.006"},{"key":"CIT0145","doi-asserted-by":"publisher","DOI":"10.1124\/mol.108.052340"},{"key":"CIT0146","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2011.05.010"},{"key":"CIT0147","doi-asserted-by":"publisher","DOI":"10.1007\/s00210-011-0688-9"},{"key":"CIT0148","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.110.174219"},{"key":"CIT0149","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M312560200"},{"key":"CIT0150","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0914611107"}],"container-title":["Expert Opinion on Investigational Drugs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/13543784.2015.1041587","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T12:46:47Z","timestamp":1651841207000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1517\/13543784.2015.1041587"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,28]]},"references-count":148,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2015,6,22]]},"published-print":{"date-parts":[[2015,7,3]]}},"alternative-id":["10.1517\/13543784.2015.1041587"],"URL":"https:\/\/doi.org\/10.1517\/13543784.2015.1041587","relation":{},"ISSN":["1354-3784","1744-7658"],"issn-type":[{"value":"1354-3784","type":"print"},{"value":"1744-7658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,28]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieid20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieid20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"}]}}