{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T06:13:50Z","timestamp":1769148830342,"version":"3.49.0"},"reference-count":70,"publisher":"Informa UK Limited","issue":"3","funder":[{"DOI":"10.13039\/501100004442","name":"National Science Centre","doi-asserted-by":"crossref","award":["#UMO-2013\/11\/N\/NZ7\/02354"],"award-info":[{"award-number":["#UMO-2013\/11\/N\/NZ7\/02354"]}],"id":[{"id":"10.13039\/501100004442","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004442","name":"National Science Centre","doi-asserted-by":"crossref","award":["#UMO-2014\/13\/B\/NZ4\/01179"],"award-info":[{"award-number":["#UMO-2014\/13\/B\/NZ4\/01179"]}],"id":[{"id":"10.13039\/501100004442","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004442","name":"National Science Centre","doi-asserted-by":"crossref","award":["#UMO-2015\/16\/T\/NZ7\/00031"],"award-info":[{"award-number":["#UMO-2015\/16\/T\/NZ7\/00031"]}],"id":[{"id":"10.13039\/501100004442","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004442","name":"National Science Centre","doi-asserted-by":"crossref","award":["UMO-2013\/11\/B\/NZ7\/01301"],"award-info":[{"award-number":["UMO-2013\/11\/B\/NZ7\/01301"]}],"id":[{"id":"10.13039\/501100004442","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100005888","name":"Medical University of Lodz","doi-asserted-by":"crossref","award":["#503\/1-156-04\/503-01"],"award-info":[{"award-number":["#503\/1-156-04\/503-01"]}],"id":[{"id":"10.13039\/501100005888","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100005888","name":"Medical University of Lodz","doi-asserted-by":"crossref","award":["502-03\/1-156-04\/502-14-140"],"award-info":[{"award-number":["502-03\/1-156-04\/502-14-140"]}],"id":[{"id":"10.13039\/501100005888","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100005888","name":"Medical University of Lodz","doi-asserted-by":"crossref","award":["UMED Grant's\/63\/2014-2015"],"award-info":[{"award-number":["UMED Grant's\/63\/2014-2015"]}],"id":[{"id":"10.13039\/501100005888","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Investigational Drugs"],"published-print":{"date-parts":[[2016,3,3]]},"DOI":"10.1517\/13543784.2016.1142532","type":"journal-article","created":{"date-parts":[[2016,1,15]],"date-time":"2016-01-15T02:07:54Z","timestamp":1452823674000},"page":"275-286","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":14,"title":["Novel investigational drugs for constipation-predominant irritable bowel syndrome: a review"],"prefix":"10.1517","volume":"25","author":[{"given":"Paula","family":"Mosi\u0144ska","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maciej","family":"Salaga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jakub","family":"Fichna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2016,2,4]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.11.061"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2012.00127"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1177\/1756283X15587866"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.2165\/00019053-200624010-00002"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.5009\/gnl.2011.5.3.253"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-014-3244-x"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1586\/egh.11.30"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2010.09.019"},{"key":"CIT0009","first-page":"39","volume":"7","author":"Lee N","year":"2012","journal-title":"Core Evid"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12158"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i24.7436"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-381517-0.00012-6"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2007.01079.x"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2008.03870.x"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00076.2012"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2012.05.006"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2013.04.020"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1002\/phar.1594"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.2013.753056"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2011.04675.x"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2011.285"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2011.162"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2010.07.052"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2008.07.003"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2013.105"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2013-304901"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.09.031"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1007\/s11894-010-0124-1"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2010.12.002"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2010.227546"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.1998.00268.x"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1254\/jjp.90.313"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2008.01128.x"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1540\/jsmr.42.139"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20387"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2009.09.024"},{"key":"CIT0037","first-page":"416","volume":"8","author":"Evangelista S","year":"2007","journal-title":"Curr Opin Investig Drugs"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1159\/000109984"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2003.01797.x"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2710.2005.00695.x"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1007\/s00210-008-0281-z"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1007\/s00210-008-0282-y"},{"key":"CIT0043","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1111\/j.1365-2982.2009.01378.x","volume":"22","author":"Manini ML","year":"2010","journal-title":"Neurogastroenterol Motil"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2010.04456.x"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2010.04504.x"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12458"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2014.08.012"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.2010.482927"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.12.041"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.110.037564"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2006.00865.x"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2014.03.061"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12574"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1097\/MOG.0b013e328341ead5"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.112.199430"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S32252"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.4292\/wjgpt.v6.i4.213"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1097\/MNH.0000000000000154"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1007\/s00424-008-0579-1"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.2015.1054480"},{"key":"CIT0062","doi-asserted-by":"crossref","first-page":"e00165","DOI":"10.1002\/prp2.165","volume":"3","author":"Watanabe J","year":"2015","journal-title":"Pharmacol Res Perspect"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.5056\/jnm15120"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1111\/apt.12264"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1254\/jjp.71.129"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2008.49.3.472"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12272"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0704293"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2009.12.005"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2007.11.012"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-5949.2010.00172.x"}],"container-title":["Expert Opinion on Investigational Drugs"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/13543784.2016.1142532","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T20:27:41Z","timestamp":1718310461000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1517\/13543784.2016.1142532"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,4]]},"references-count":70,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2016,1,12]]},"published-print":{"date-parts":[[2016,3,3]]}},"alternative-id":["10.1517\/13543784.2016.1142532"],"URL":"https:\/\/doi.org\/10.1517\/13543784.2016.1142532","relation":{},"ISSN":["1354-3784","1744-7658"],"issn-type":[{"value":"1354-3784","type":"print"},{"value":"1744-7658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,4]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieid20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieid20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"}]}}