{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T03:30:30Z","timestamp":1769398230207,"version":"3.49.0"},"reference-count":131,"publisher":"Informa UK Limited","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Expert Opinion on Investigational Drugs"],"published-print":{"date-parts":[[2000,5]]},"DOI":"10.1517\/13543784.9.5.1065","type":"journal-article","created":{"date-parts":[[2005,5,4]],"date-time":"2005-05-04T19:05:19Z","timestamp":1115233519000},"page":"1065-1078","source":"Crossref","is-referenced-by-count":11,"title":["Necatoriasis: treatment and developmental therapeutics"],"prefix":"10.1517","volume":"9","author":[{"given":"Vassil St","family":"Georgiev","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2005,2,24]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1038\/scientificamerican0695-68"},{"issue":"2","key":"CIT0002","first-page":"130","volume":"12","author":"SARINAS PS","year":"1997","journal-title":"Semin. Respir. Infect."},{"key":"CIT0005","doi-asserted-by":"crossref","first-page":"3883","DOI":"10.1128\/IAI.58.12.3883-3892.1990","volume":"58","author":"HOTEZ P","year":"1990","journal-title":"Infect. Immunol."},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3024.1993.tb00600.x"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(74)90006-X"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(78)90303-6"},{"key":"CIT0009","first-page":"589","volume":"3","author":"PHILLIPP M","year":"1984","journal-title":"1. Evidence for secretion of the enzyme by a number of nematode species. Int. J. Parasitol."},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(90)81522-P"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7519(97)00213-0"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.1997.tb01609.x"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(87)90369-5"},{"key":"CIT0016","doi-asserted-by":"crossref","first-page":"126","DOI":"10.4269\/ajtmh.1987.37.126","volume":"37","author":"MAXWELL C","year":"1987","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"CIT0017","doi-asserted-by":"crossref","first-page":"387","DOI":"10.4269\/ajtmh.1984.33.387","volume":"33","author":"CLINE BL","year":"1984","journal-title":"Am. J. Trop. Hyg."},{"key":"CIT0018","first-page":"1","volume":"1","author":"BEAVER PC","year":"1955","journal-title":"Rev. Iberica Parasitol"},{"key":"CIT0019","first-page":"545","volume":"13","author":"BIROUM-NERJASIN N","year":"1973","journal-title":"Clin. Exp. Immunol."},{"key":"CIT0020","doi-asserted-by":"crossref","first-page":"913","DOI":"10.4269\/ajtmh.1972.21.913","volume":"21","author":"KOJIMA S","year":"1972","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"CIT0021","first-page":"565","volume":"18","author":"GROVE DI","year":"1978","journal-title":"Gin. Exp. Immunol"},{"key":"CIT0022","first-page":"162","volume":"64","author":"CAPPUCCINELLI P","year":"1971","journal-title":"II. Significance of raised IgE levels in different protozoal and helminthic infections. J. Bacteriol Vim]. Immunol."},{"key":"CIT0023","first-page":"531","volume":"71","author":"KUMAR N","year":"1980","journal-title":"Indian J. Med. Res."},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(68)90187-6"},{"key":"CIT0025","first-page":"285","volume":"47","author":"RADERMEEKER M","year":"1974","journal-title":"Allergy"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3024.1995.tb00897.x"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3024.1995.tb00968.x"},{"issue":"4","key":"CIT0030","first-page":"381","volume":"74","author":"PALMER DR","year":"1996","journal-title":"Bull. World Health Organ."},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3024.1995.tb01005.x"},{"issue":"3","key":"CIT0032","first-page":"221","volume":"23","author":"OLATUNDE BO","year":"1994","journal-title":"Afr. J. Med. Sci."},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(92)90033-H"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(91)90239-U"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1016\/S1054-3589(08)60022-8"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1016\/0169-4758(90)90232-S"},{"key":"CIT0042","first-page":"185","volume":"39","author":"FELDMEIER H","year":"1982","journal-title":"Acta Trop."},{"key":"CIT0043","doi-asserted-by":"crossref","first-page":"118","DOI":"10.4269\/ajtmh.1983.32.118","volume":"32","author":"KAN SP","year":"1983","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-91-4-582"},{"issue":"2","key":"CIT0045","first-page":"237","volume":"20","author":"NONTASUT P","year":"1989","journal-title":"Southeast Asian Trop. Med. Public Health"},{"key":"CIT0046","doi-asserted-by":"crossref","first-page":"263","DOI":"10.4269\/ajtmh.1982.31.263","volume":"31","author":"PENE P","year":"1982","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"CIT0047","first-page":"654","volume":"13","author":"VIRAVAN C","year":"1982","journal-title":"Southeast Asian J. Trop. Med. Public Health"},{"key":"CIT0048","doi-asserted-by":"crossref","first-page":"984","DOI":"10.4269\/ajtmh.1983.32.984","volume":"32","author":"RAMALINGAM S","year":"1983","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(92)90215-X"},{"key":"CIT0050","first-page":"226","volume":"8","author":"JAGOTA SC","year":"1986","journal-title":"Clin. Ther."},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1016\/0169-4758(90)90227-U"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199605023341808"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(94)90174-0"},{"key":"CIT0054","first-page":"142","volume":"46","author":"ALBONICO M","year":"1994","journal-title":"Trop. Geog. Med."},{"key":"CIT0055","first-page":"162","volume":"36","author":"ISMAIL MM","year":"1991","journal-title":"Ceylon Med. J."},{"key":"CIT0056","first-page":"749","author":"WORLD HEALTH ORGANIZATION","year":"1987","journal-title":"WHO Tech. Rep. Ser."},{"key":"CIT0057","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.58837\/CHULA.CMJ.29.10.3","volume":"29","author":"KULKUMTHORN M","year":"1985","journal-title":"Chulalongkorn Med. J."},{"key":"CIT0058","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1080\/00034983.1978.11719280","volume":"72","author":"CHONGSUPHAJAISIDDHI T","year":"1978","journal-title":"Ann. Trop. Med. Parasitol"},{"issue":"2","key":"CIT0059","first-page":"326","volume":"28","author":"NONTASUT P","year":"1997","journal-title":"Southeast Asian J. Trop. Med. Public Health"},{"key":"CIT0060","first-page":"211","volume":"18","author":"NONTASUT P","year":"1987","journal-title":"Southeast Asian J. Trop. Med. Public Health"},{"key":"CIT0061","doi-asserted-by":"crossref","first-page":"592","DOI":"10.4269\/ajtmh.1973.22.592","volume":"22","author":"CHAVARRIA AP","year":"1973","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"CIT0062","first-page":"502","volume":"11","author":"CABRERA BD","year":"1980","journal-title":"Southeast Asian J. Trop. Med. Public Health"},{"key":"CIT0063","first-page":"444","volume":"74","author":"RICHARD-LENOBLE D","year":"1981","journal-title":"Bull. Soc. Path. ExoL Filiales"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1007\/BF02456002"},{"key":"CIT0065","first-page":"41","volume":"28","author":"SHIELD J","year":"1985","journal-title":"P. N G. Med. J."},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(83)90211-0"},{"key":"CIT0067","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1080\/00034983.1985.11811890","volume":"79","author":"MAISSONEUVE H","year":"1995","journal-title":"Ann. Trop. Med. Parasitol."},{"key":"CIT0068","first-page":"870","volume":"85","author":"TAYLOR M","year":"1995","journal-title":"S. Afr. Med. J."},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(90)90160-G"},{"issue":"2","key":"CIT0070","first-page":"96","volume":"8","author":"ZHANG XR","year":"1990","journal-title":"Chung Kuo Chi Sheng Chung Hsueh Yu Chi Sheng Chung Ping Tsa Chih"},{"key":"CIT0071","first-page":"185","volume":"34","author":"DE SILVA DG","year":"1989","journal-title":"Ceylon Med. J."},{"key":"CIT0073","doi-asserted-by":"crossref","first-page":"151","DOI":"10.4269\/ajtmh.1974.23.151","volume":"23","author":"WAGNER ED","year":"1974","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"CIT0074","doi-asserted-by":"crossref","first-page":"203","DOI":"10.4269\/ajtmh.1978.27.203","volume":"27","author":"WAGNER ED","year":"1978","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"CIT0075","first-page":"197","volume":"66","author":"PAMBA HO","year":"1989","journal-title":"East Afr. Med. J."},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(99)90306-1"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(95)00036-2"},{"key":"CIT0078","first-page":"608","volume":"15","author":"CAMPBELL WC","year":"1983","journal-title":"J. Nematology"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2885.1984.tb00872.x"},{"key":"CIT0080","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(93)90061-3"},{"key":"CIT0081","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1080\/00034983.1986.11812076","volume":"80","author":"RAJASEKARIAH GR","year":"1986","journal-title":"Ann. Trop. Med. Parasitol"},{"key":"CIT0082","first-page":"279","volume":"10","author":"XIA ZH","year":"1992","journal-title":"Chung Kuo Chi Sheng Chung Hsueh Yu Chi Sheng Chung Ping Tsa Chih"},{"key":"CIT0083","doi-asserted-by":"crossref","first-page":"304","DOI":"10.4269\/ajtmh.1989.40.304","volume":"40","author":"NAQUIRA C","year":"1989","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"CIT0084","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(91)90037-Y"},{"issue":"0","key":"CIT0085","first-page":"90","volume":"10","author":"XIAO SH","year":"1989","journal-title":"Chung Kuo Yao Li Hsueh Pao"},{"key":"CIT0086","first-page":"264","volume":"9","author":"YANG YQ","year":"1988","journal-title":"Chung Kuo Yao Li Hsueh Pao"},{"key":"CIT0087","first-page":"73","volume":"35","author":"KUMAR S","year":"1987","journal-title":"Rev. Biol. Trop."},{"key":"CIT0089","first-page":"165","volume":"66","author":"VANDEPITTE J","year":"1973","journal-title":"Bull. Soc. Pathol. ExoL Filiales"},{"key":"CIT0090","first-page":"698","volume":"76","author":"PENICAUT B","year":"1983","journal-title":"Bull. Soc. Pathol Exot. Fihales"},{"key":"CIT0091","doi-asserted-by":"publisher","DOI":"10.1007\/BF00558451"},{"key":"CIT0093","doi-asserted-by":"publisher","DOI":"10.1016\/0169-4758(90)90230-2"},{"key":"CIT0094","doi-asserted-by":"publisher","DOI":"10.1016\/0169-4758(94)90075-2"},{"key":"CIT0095","first-page":"1","volume":"35","author":"CONDOR GA","year":"1995","journal-title":"Arch. Parasitol."},{"key":"CIT0097","doi-asserted-by":"publisher","DOI":"10.1016\/0169-4758(95)80152-9"},{"key":"CIT0098","doi-asserted-by":"publisher","DOI":"10.1016\/0169-4758(94)90234-8"},{"key":"CIT0100","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(75)90073-9"},{"key":"CIT0101","first-page":"7","volume":"37","author":"WESHE D","year":"1994","journal-title":"P. N G. Med. J."},{"key":"CIT0102","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-198908000-00009"},{"key":"CIT0103","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(63)90029-8"},{"key":"CIT0104","first-page":"141","volume":"19","author":"WOODRUFF AW","year":"1982","journal-title":"Semin. Haematol"},{"key":"CIT0106","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.4269\/ajtmh.1974.23.1046","volume":"23","author":"KALKOFEN UP","year":"1974","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"CIT0107","doi-asserted-by":"publisher","DOI":"10.1126\/science.119.3091.412"},{"key":"CIT0108","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.4269\/ajtmh.1966.15.1032","volume":"15","author":"ROCHE M","year":"1966","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"CIT0109","first-page":"1","volume":"33","author":"GILES HM","year":"1964","journal-title":"Q. J. Med."},{"key":"CIT0110","first-page":"173","volume":"7","author":"LOEB L","year":"1904","journal-title":"Proc. Pathol. Soc."},{"key":"CIT0111","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/7.5.625"},{"key":"CIT0112","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.13.6152"},{"key":"CIT0113","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/167.6.1474"},{"issue":"3","key":"CIT0114","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1055\/s-0038-1653811","volume":"73","author":"PRITCHARD DI","year":"1995","journal-title":"Thromb. HaemosL"},{"key":"CIT0115","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1055\/s-0038-1653811","volume":"73","author":"FURMIDGE BA","year":"1995","journal-title":"Thromb. HaemosL"},{"key":"CIT0116","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000065100"},{"key":"CIT0117","doi-asserted-by":"publisher","DOI":"10.2307\/3276520"},{"key":"CIT0118","first-page":"922","volume":"4","author":"SPELLMAN GG","year":"1971","journal-title":"Am. J. Parasitol."},{"key":"CIT0119","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1055\/s-0038-1661063","volume":"51","author":"CAROLL SM","year":"1984","journal-title":"Thromb. Haemost."},{"key":"CIT0120","doi-asserted-by":"publisher","DOI":"10.1084\/jem.157.5.1594"},{"key":"CIT0121","doi-asserted-by":"crossref","first-page":"7343","DOI":"10.1016\/S0021-9258(17)39614-X","volume":"260","author":"HOTEZ PJ","year":"1985","journal-title":"J. Biol. Chem."},{"key":"CIT0122","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.1987.tb01434.x"},{"key":"CIT0123","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.74.9.4033"},{"key":"CIT0124","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1055\/s-0038-1646371","volume":"66","author":"HYNES RO","year":"1991","journal-title":"Thromb. Haemost."},{"key":"CIT0125","doi-asserted-by":"publisher","DOI":"10.1172\/JCI110448"},{"key":"CIT0126","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1974.tb06660.x"},{"key":"CIT0127","doi-asserted-by":"crossref","first-page":"5269","DOI":"10.1016\/S0021-9258(18)32568-7","volume":"258","author":"MCEVER RP","year":"1983","journal-title":"J. Biol. Chem."},{"key":"CIT0128","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1055\/s-0038-1646195","volume":"70","author":"SHATTIL SJ","year":"1993","journal-title":"Thromb. Haemost."},{"key":"CIT0129","doi-asserted-by":"crossref","first-page":"11107","DOI":"10.1016\/S0021-9258(17)39154-8","volume":"260","author":"SHATTIL SJ","year":"1985","journal-title":"J. Biol. Chem."},{"key":"CIT0130","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000061333"},{"key":"CIT0131","first-page":"7","volume":"19","author":"COOK JD","year":"1982","journal-title":"Semin. Haematol."},{"key":"CIT0132","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1093\/ajcn\/39.3.471","volume":"39","author":"FINCH CA","year":"1984","journal-title":"Am. J. Clin. Nutr."},{"key":"CIT0133","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(91)90038-Z"},{"key":"CIT0134","doi-asserted-by":"crossref","first-page":"399","DOI":"10.4269\/ajtmh.1996.55.399","volume":"55","author":"STOLTZFUS RJ","year":"1996","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"CIT0135","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1093\/clinchem\/29.12.2061","volume":"29","author":"SCHWARTZ S","year":"1983","journal-title":"Clin. Chem."},{"key":"CIT0136","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(91)70785-2"},{"key":"CIT0138","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1997.tb03726.x"},{"key":"CIT0141","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(69)90011-X"},{"key":"CIT0142","first-page":"319","volume":"33","author":"BEAVER PC","year":"1964","journal-title":"Industrial Med. Surg."},{"key":"CIT0143","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1993.01680260058006"},{"key":"CIT0144","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1990.tb08245.x"},{"key":"CIT0145","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1990.01670270130026"},{"key":"CIT0146","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1994.tb03400.x"},{"key":"CIT0147","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1965.01600110013004"},{"key":"CIT0148","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1992.01680170130027"},{"key":"CIT0149","doi-asserted-by":"publisher","DOI":"10.1097\/00001432-199410000-00009"},{"key":"CIT0150","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268800049980"},{"key":"CIT0151","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1999.tb01347.x"}],"container-title":["Expert Opinion on Investigational Drugs"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/13543784.9.5.1065","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T16:02:59Z","timestamp":1706198579000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1517\/13543784.9.5.1065"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,5]]},"references-count":131,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2005,2,24]]},"published-print":{"date-parts":[[2000,5]]}},"alternative-id":["10.1517\/13543784.9.5.1065"],"URL":"https:\/\/doi.org\/10.1517\/13543784.9.5.1065","relation":{},"ISSN":["1354-3784","1744-7658"],"issn-type":[{"value":"1354-3784","type":"print"},{"value":"1744-7658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,5]]}}}