{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T15:53:36Z","timestamp":1774281216788,"version":"3.50.1"},"reference-count":75,"publisher":"Informa Healthcare","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Expert Opinion on Investigational Drugs"],"published-print":{"date-parts":[[2000,7]]},"DOI":"10.1517\/13543784.9.7.1491","type":"journal-article","created":{"date-parts":[[2005,5,4]],"date-time":"2005-05-04T15:10:30Z","timestamp":1115219430000},"page":"1491-1498","source":"Crossref","is-referenced-by-count":16,"title":["Tetracyclines for the treatment of rheumatoid arthritis"],"prefix":"10.1517","volume":"9","author":[{"given":"Graciela S","family":"Alarc\u00f3n","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3197","published-online":{"date-parts":[[2005,2,24]]},"reference":[{"key":"CIT0001","first-page":"190","volume":"3","author":"GREENWALD RA","year":"1995","journal-title":"J. Clin. Rheumatol."},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-199409000-00017"},{"key":"CIT0003","first-page":"1","volume":"5","author":"ALARCON GS","year":"1995","journal-title":"Clin. Rheumatol."},{"key":"CIT0004","first-page":"22","volume":"82","author":"SANCHEZ I","year":"1968","journal-title":"[Tetracycline treatment in rheumatoid arthritis and other rheumatic diseases]. Brasil Med."},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780080306"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1988.00380040209029"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(70)91328-0"},{"key":"CIT0008","first-page":"1","author":"BROWN TM","year":"1992","journal-title":"The Scanner"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/38.6.504"},{"key":"CIT0010","first-page":"S85","author":"BROWN TM","year":"1985","journal-title":"Proceedings of Meeting). InL Con. Rheumatol."},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780140607"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780200102"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1177\/00220345870660080401"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1994.tb24728.x"},{"key":"CIT0015","first-page":"80","author":"GOLUB LM","year":"1992","journal-title":"Curr. Opin. Den."},{"key":"CIT0016","first-page":"1502","volume":"19","author":"LANGEVITZ P","year":"1992","journal-title":"J. Rheumatol."},{"key":"CIT0017","first-page":"43","volume":"17","author":"BREEDVELD FC","year":"1990","journal-title":"J. Rheumatol"},{"key":"CIT0018","first-page":"629","volume":"37","author":"KLOPPENBURG M","year":"1994","journal-title":"A double-blind, placebo-controlled trial. Arthritis Rheum."},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-122-2-199501150-00001"},{"key":"CIT0020","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1002\/art.1780400510","volume":"40","author":"O'DELL JR","year":"1997","journal-title":"Treatment ofearly rheumatoid arthritis with minocycline or placebo: results of a randomized, double-blind, placebo- controlled trial. Arthritis Rheum."},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1985.tb00405.x"},{"key":"CIT0023","first-page":"24","volume":"56","author":"GOLUB LM","year":"1990","journal-title":"New York St. Dental J."},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1097\/00002281-199605000-00013"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.24.14014"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780351007"},{"key":"CIT0027","first-page":"1450","volume":"18","author":"YU LPJ SMITH GNJ","year":"1991","journal-title":"J. Rheumatol."},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(92)90381-R"},{"key":"CIT0029","first-page":"927","volume":"19","author":"GREENWALD RA","year":"1992","journal-title":"J. Rheumatol."},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.36.1.227"},{"key":"CIT0031","first-page":"3","volume":"7","author":"GREENWALD RA","year":"1988","journal-title":"Medguide Inflamm. Dis."},{"key":"CIT0032","first-page":"28","volume":"14","author":"GREENWALD RA","year":"1987","journal-title":"J. Rheumatol."},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.5650071111"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(96)00168-2"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1984.tb01334.x"},{"key":"CIT0037","first-page":"419","volume":"732","author":"GREENWALD RA","year":"1994","journal-title":"In: Inhibition of matrix metalloproteinase: therapeutic potential. Ann. NY Acad. Sci."},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1006\/cimm.1996.0027"},{"key":"CIT0039","first-page":"611","volume":"22","author":"KLOPPENBURG M","year":"1995","journal-title":"J. Rheumatol."},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(83)80010-3"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1991.tb01626.x"},{"key":"CIT0042","first-page":"443","volume":"35","author":"THONG YH","year":"1979","journal-title":"Clin. Exp. Immunol."},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-122-11-199506010-00011"},{"key":"CIT0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/oxfordjournals.epirev.a036019","volume":"10","author":"FELSON DT","year":"1988","journal-title":"[Review]. Epidemiol. Rev."},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-857X(05)70022-3"},{"key":"CIT0049","first-page":"1277","volume":"322","author":"HARRIS EDJ","year":"1990","journal-title":"Pathophysiology and implications for therapy. N Engl. J. Med."},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1994.00420140105013"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-127-2-199707150-00030"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(92)70251-A"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-117-6-476"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1378\/chest.115.5.1471"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1984.00350190199034"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6162.524"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.312.7024.169"},{"key":"CIT0058","first-page":"S191","volume":"40","author":"AKIN E","year":"1997","journal-title":"Arthritis Rheum."},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(98)00325-8"},{"key":"CIT0061","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1177\/120347549800300211","volume":"3","author":"WASEL NR","year":"1998","journal-title":"J. Cutan. Med. Surg."},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1997.68.1.84"},{"key":"CIT0063","first-page":"939","volume":"115","author":"RUMBAK MJ","year":"1991","journal-title":"Arch. Pathol. Lab. Med."},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1980.03310100021021"},{"key":"CIT0065","first-page":"229","volume":"40","author":"ANGELONI VL","year":"1987","journal-title":"Cutts"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1992.01680140149027"},{"key":"CIT0067","first-page":"1691","volume":"42","author":"O'DELL JR","year":"1999","journal-title":"Treatment of early seropositive rheumatoid arthritis with minocy-line: four-year followup of a double-blind, placebo-controlled trial. Arthritis Rheum."},{"key":"CIT0069","first-page":"2","volume":"45","author":"PANUSH RS","year":"1996","journal-title":"Rheum. Dis."},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-122-2-199501150-00012"},{"key":"CIT0071","first-page":"474","volume":"64","author":"TOUSSIROT E","year":"1997","journal-title":"Rhuma. (English)"},{"key":"CIT0072","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1177\/106002809502900215","volume":"29","author":"KIM NM","year":"2000","journal-title":"Ann. Pharmacother."},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1016\/S0950-3579(05)80309-7"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780400503"},{"key":"CIT0075","first-page":"1295","volume":"24","author":"BLUHM GB","year":"1997","journal-title":"J. Rheumatol"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780391105"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1007\/s002960050042"},{"key":"CIT0078","first-page":"801","volume":"38","author":"KAWANAKA N","year":"1998","journal-title":"Ryumachi"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1097\/00124743-199908000-00011"},{"key":"CIT0080","first-page":"817","volume":"21","author":"TRENTHAM DE","year":"1995","journal-title":"Scientific and anecdotal appraisals. Rheum. Dis. Chin. N Am."},{"key":"CIT0081","first-page":"S155","volume":"41","author":"MORELAND LW","year":"1998","journal-title":"placebo vs. methotrexate in early and late rheumatoid arthritis. Arthritis Rheum."},{"key":"CIT0082","first-page":"7","volume":"57","author":"MORELAND LW","year":"1999","journal-title":"J. Rheumatol"}],"container-title":["Expert Opinion on Investigational Drugs"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/13543784.9.7.1491","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,17]],"date-time":"2019-02-17T17:14:02Z","timestamp":1550423642000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1517\/13543784.9.7.1491"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,7]]},"references-count":75,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2005,2,24]]},"published-print":{"date-parts":[[2000,7]]}},"alternative-id":["10.1517\/13543784.9.7.1491"],"URL":"https:\/\/doi.org\/10.1517\/13543784.9.7.1491","relation":{},"ISSN":["1354-3784","1744-7658"],"issn-type":[{"value":"1354-3784","type":"print"},{"value":"1744-7658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,7]]}}}