{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T08:37:57Z","timestamp":1774946277066,"version":"3.50.1"},"reference-count":93,"publisher":"Informa UK Limited","issue":"2","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Pharmacotherapy"],"published-print":{"date-parts":[[2014,2]]},"DOI":"10.1517\/14656566.2014.861818","type":"journal-article","created":{"date-parts":[[2013,11,28]],"date-time":"2013-11-28T04:44:31Z","timestamp":1385613871000},"page":"193-202","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":16,"title":["Opioids for the treatment of arthritis pain"],"prefix":"10.1517","volume":"15","author":[{"given":"Christoph","family":"Stein","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Baerwald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2013,11,27]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1126\/science.1230720"},{"issue":"5","key":"CIT0002","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1056\/NEJMra1201534","volume":"369","author":"Murray CJ","year":"2013","journal-title":"N Engl J Med"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.092163"},{"key":"CIT0004","doi-asserted-by":"crossref","first-page":"c7086","DOI":"10.1136\/bmj.c7086","volume":"342","author":"Trelle S","year":"2011","journal-title":"BMJ"},{"issue":"6","key":"CIT0005","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1056\/NEJMe1206315","volume":"367","author":"Fox DA","year":"2012","journal-title":"N Engl J Med"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1002\/acr.21641"},{"issue":"8","key":"CIT0007","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1007\/s00108-008-2059-2","volume":"49","author":"Pierer M","year":"2008","journal-title":"Internist (Berl)"},{"key":"CIT0008","author":"Albrecht K","year":"2013","journal-title":"Rheumatol Int"},{"key":"CIT0009","author":"Perrot S","year":"2013","journal-title":"Pain Med"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199301000-00031"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1124\/pr.110.003145"},{"issue":"37","key":"CIT0012","doi-asserted-by":"crossref","first-page":"6053","DOI":"10.2174\/138161212803582513","volume":"18","author":"Stein C","year":"2012","journal-title":"Curr Pharm Des"},{"key":"CIT0013","first-page":"531","volume-title":"Basic and clinical pharmacology","author":"Schumacher MA","year":"2009","edition":"11"},{"key":"CIT0014","first-page":"37","volume-title":"Rheuma und schmerz","author":"Dohrenbusch R","year":"2004"},{"issue":"5","key":"CIT0015","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1097\/ACO.0b013e32833c57a8","volume":"23","author":"Stein C","year":"2010","journal-title":"Curr Opin Anaesthesiol"},{"issue":"1","key":"CIT0016","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.pain.2006.06.009","volume":"125","author":"Eriksen J","year":"2006","journal-title":"Pain"},{"issue":"6","key":"CIT0017","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.tips.2013.03.006","volume":"34","author":"Stein C","year":"2013","journal-title":"Trends Pharmacol Sci"},{"issue":"1","key":"CIT0018","first-page":"300","volume":"15","author":"Lee YC","year":"2013","journal-title":"CurrRheumatol Rep"},{"issue":"5","key":"CIT0019","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1002\/acr.20005","volume":"62","author":"ACR Pain Management Task Force","year":"2010","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"CIT0020","first-page":"56","volume-title":"Rheuma und schmerz","author":"Wendler J","year":"2004"},{"issue":"2","key":"CIT0021","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2165\/00019053-200422001-00002","volume":"22","author":"Kvien TK","year":"2004","journal-title":"Pharmacoeconomics"},{"issue":"8","key":"CIT0022","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1093\/rheumatology\/keg281","volume":"42","author":"Minnock P","year":"2003","journal-title":"Rheumatology (Oxford)"},{"issue":"4","key":"CIT0023","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1002\/art.10515","volume":"47","author":"Heiberg T","year":"2002","journal-title":"Arthritis Rheum"},{"issue":"11","key":"CIT0024","first-page":"CD003113","author":"Whittle SL","year":"2011","journal-title":"Cochrane Database SystRev"},{"issue":"7","key":"CIT0025","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1093\/rheumatology\/ken193","volume":"47","author":"Grijalva CG","year":"2008","journal-title":"Rheumatology (Oxford)"},{"issue":"2","key":"CIT0026","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.rdc.2008.04.004","volume":"34","author":"Katz WA","year":"2008","journal-title":"RheumDis Clin North Am"},{"issue":"2","key":"CIT0027","first-page":"137","volume":"16","author":"Zhang W","year":"2008","journal-title":"OsteoarthritisCartilage"},{"issue":"4","key":"CIT0028","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1002\/acr.21596","volume":"64","author":"Hochberg MC","year":"2012","journal-title":"Arthritis Care Res(Hoboken)"},{"issue":"4","key":"CIT0029","first-page":"CD003115","author":"N\u00fcesch E","year":"2009","journal-title":"Cochrane Database SystRev"},{"issue":"9","key":"CIT0030","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1111\/j.1526-4637.2012.01454.x","volume":"13","author":"Kavanagh S","year":"2012","journal-title":"Pain Med"},{"issue":"1","key":"CIT0031","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.ejpain.2006.01.003","volume":"11","author":"Hutchinson K","year":"2007","journal-title":"Eur J Pain"},{"issue":"5","key":"CIT0032","doi-asserted-by":"crossref","first-page":"R1046","DOI":"10.1186\/ar1782","volume":"7","author":"Moore RA","year":"2005","journal-title":"Arthritis ResTher"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-155-5-201109060-00011"},{"issue":"13","key":"CIT0034","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1001\/jama.2011.370","volume":"305","author":"Bohnert AS","year":"2011","journal-title":"JAMA"},{"issue":"1","key":"CIT0035","first-page":"10","volume":"61","author":"Paulozzi L","year":"2012","journal-title":"Morbidity and Mortality Weekly Report"},{"issue":"4","key":"CIT0036","first-page":"45","volume":"110","author":"Schubert I","year":"2013","journal-title":"Dtsch Arztebl Int"},{"issue":"8","key":"CIT0037","first-page":"957","volume":"15","author":"Avouac J","year":"2007","journal-title":"OsteoarthritisCartilage"},{"issue":"1","key":"CIT0038","first-page":"CD008951","author":"Radner H","year":"2012","journal-title":"Cochrane Database SystRev"},{"issue":"10","key":"CIT0039","first-page":"CD008952","author":"Marks JL","year":"2011","journal-title":"Cochrane Database SystRev"},{"issue":"22","key":"CIT0040","first-page":"1968","volume":"170","author":"Solomon DH","year":"2010","journal-title":"ArchIntern Med"},{"issue":"3","key":"CIT0041","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1111\/j.1532-5415.2011.03318.x","volume":"59","author":"Miller M","year":"2011","journal-title":"J Am GeriatrSoc"},{"issue":"1","key":"CIT0042","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1124\/mol.106.026740","volume":"71","author":"Endres-Becker J","year":"2007","journal-title":"Mol Pharmacol"},{"issue":"4","key":"CIT0043","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.pain.2012.12.026","volume":"154","author":"Spahn V","year":"2013","journal-title":"Pain"},{"issue":"28","key":"CIT0044","doi-asserted-by":"crossref","first-page":"19540","DOI":"10.1074\/jbc.M707865200","volume":"283","author":"Vetter I","year":"2008","journal-title":"J Biol Chem"},{"issue":"10","key":"CIT0045","doi-asserted-by":"crossref","first-page":"2827","DOI":"10.1152\/jn.00082.2012","volume":"108","author":"Moshourab R","year":"2012","journal-title":"J Neurophysiol"},{"issue":"8","key":"CIT0046","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1002\/emmm.201201980","volume":"5","author":"Nockemann D","year":"2013","journal-title":"EMBO Mol Med"},{"issue":"3","key":"CIT0047","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0304-3959(02)00019-2","volume":"98","author":"Kalso E","year":"2002","journal-title":"Pain"},{"issue":"8","key":"CIT0048","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1038\/nm908","volume":"9","author":"Stein C","year":"2003","journal-title":"Nat Med"},{"issue":"1","key":"CIT0049","doi-asserted-by":"crossref","first-page":"55","DOI":"10.5055\/jom.2011.0049","volume":"7","author":"Vadivelu N","year":"2011","journal-title":"J Opioid Manag"},{"issue":"39","key":"CIT0050","doi-asserted-by":"crossref","first-page":"8825","DOI":"10.1523\/JNEUROSCI.0160-05.2005","volume":"25","author":"Patwardhan AM","year":"2005","journal-title":"J Neurosci"},{"issue":"26","key":"CIT0051","doi-asserted-by":"crossref","first-page":"10762","DOI":"10.1523\/JNEUROSCI.0123-13.2013","volume":"33","author":"Pettinger L","year":"2013","journal-title":"J Neurosci"},{"issue":"2","key":"CIT0052","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1097\/ALN.0b013e318242b2ea","volume":"116","author":"Cayla C","year":"2012","journal-title":"Anesthesiology"},{"issue":"2","key":"CIT0053","first-page":"278","volume":"119","author":"Labuz D","year":"2009","journal-title":"J Clin Invest"},{"issue":"1","key":"CIT0054","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.tvjl.2012.09.013","volume":"196","author":"Stein C","year":"2013","journal-title":"Vet J"},{"issue":"6","key":"CIT0055","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1097\/ALN.0b013e318256eeeb","volume":"116","author":"Rittner HL","year":"2012","journal-title":"Anesthesiology"},{"issue":"3","key":"CIT0056","first-page":"1065","volume":"118","author":"Z\u00f6llner C","year":"2008","journal-title":"J Clin Invest"},{"issue":"7","key":"CIT0057","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1136\/ard.2006.067066","volume":"66","author":"Mousa SA","year":"2007","journal-title":"Ann Rheum Dis"},{"key":"CIT0058","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/1744-8069-8-83","volume":"8","author":"Busch-Dienstfertig M","year":"2012","journal-title":"Mol Pain"},{"issue":"4","key":"CIT0059","doi-asserted-by":"crossref","first-page":"e1000362","DOI":"10.1371\/journal.ppat.1000362","volume":"5","author":"Rittner HL","year":"2009","journal-title":"PLoS Pathog"},{"key":"CIT0060","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/0140-6736(93)91471-W","volume":"342","author":"Stein C","year":"1993","journal-title":"Lancet"},{"issue":"4","key":"CIT0061","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1038\/nrd3673","volume":"11","author":"Roques BP","year":"2012","journal-title":"Nat Rev Drug Discov"},{"issue":"12","key":"CIT0062","doi-asserted-by":"crossref","first-page":"5161","DOI":"10.1096\/fj.12-208678","volume":"26","author":"Schreiter A","year":"2012","journal-title":"FASEB J"},{"issue":"3","key":"CIT0063","doi-asserted-by":"crossref","first-page":"E199","DOI":"10.36076\/ppj.2013\/16\/E199","volume":"16","author":"Hua S","year":"2013","journal-title":"Pain Physician"},{"issue":"3","key":"CIT0064","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1016\/S0022-3565(25)12215-5","volume":"275","author":"Craft RM","year":"1995","journal-title":"J Pharmacol Exp Ther"},{"issue":"2","key":"CIT0065","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0028-3908(01)00173-3","volume":"42","author":"Shannon HE","year":"2002","journal-title":"Neuropharmacology"},{"issue":"2","key":"CIT0066","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0304-3959(00)00365-1","volume":"89","author":"Reichert JA","year":"2001","journal-title":"Pain"},{"issue":"2","key":"CIT0067","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1124\/jpet.104.075176","volume":"312","author":"F\u00fcrst S","year":"2005","journal-title":"J Pharmacol Exp Ther"},{"key":"CIT0068","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.brainres.2007.05.049","volume":"1160","author":"Labuz D","year":"2007","journal-title":"Brain Res"},{"key":"CIT0069","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1016\/j.pain.2010.12.031","volume":"152","author":"Gaveriaux-Ruff C","year":"2011","journal-title":"Pain"},{"issue":"9","key":"CIT0070","doi-asserted-by":"crossref","first-page":"e74706","DOI":"10.1371\/journal.pone.0074706","volume":"8","author":"Weibel R","year":"2013","journal-title":"PLoS ONE"},{"issue":"1","key":"CIT0071","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1124\/pr.55.1.1","volume":"55","author":"Sawynok J","year":"2003","journal-title":"Pharmacol Rev"},{"issue":"10","key":"CIT0072","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1016\/j.pain.2013.06.016","volume":"154","author":"Graham T","year":"2013","journal-title":"Pain"},{"issue":"3","key":"CIT0073","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0304-3959(97)00040-7","volume":"72","author":"Picard PR","year":"1997","journal-title":"Pain"},{"issue":"4","key":"CIT0074","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.ejpain.2007.07.009","volume":"12","author":"Dahan A","year":"2008","journal-title":"Eur J Pain"},{"issue":"4","key":"CIT0075","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.ejpain.2010.09.007","volume":"15","author":"Binning AR","year":"2011","journal-title":"Eur J Pain"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1016\/0028-3908(85)90072-3"},{"issue":"1","key":"CIT0077","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0304-3959(94)90186-4","volume":"58","author":"Maldonado R","year":"1994","journal-title":"Pain"},{"key":"CIT0078","first-page":"131","volume-title":"International Workshop on Biological Processes & Petri Nets","author":"Bl\u00e4tke MA","year":"2010"},{"issue":"1","key":"CIT0079","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.jbiotec.2010.01.001","volume":"148","author":"K\u00fcchler S","year":"2010","journal-title":"J Biotechnol"},{"issue":"1","key":"CIT0080","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1523\/JNEUROSCI.15-01-00165.1995","volume":"15","author":"Antonijevic I","year":"1995","journal-title":"J Neurosci"},{"issue":"29","key":"CIT0081","doi-asserted-by":"crossref","first-page":"E2018","DOI":"10.1073\/pnas.1120800109","volume":"109","author":"Hackel D","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"CIT0082","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.ejphar.2013.01.076","volume":"716","author":"Stein C","year":"2013","journal-title":"Eur J Pharmacol"},{"issue":"3","key":"CIT0083","first-page":"S11","volume":"7","author":"Baker DE","year":"2007","journal-title":"Rev Gastroenterol Disord"},{"issue":"9","key":"CIT0084","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1172\/JCI200316750","volume":"111","author":"Philippe D","year":"2003","journal-title":"J Clin Invest"},{"issue":"2","key":"CIT0085","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1002\/art.23206","volume":"58","author":"Straub RH","year":"2008","journal-title":"Arthritis Rheum"},{"issue":"1","key":"CIT0086","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1385\/JMN:22:1-2:125","volume":"22","author":"McDougall JJ","year":"2004","journal-title":"J Mol Neurosci"},{"issue":"5","key":"CIT0087","first-page":"971","volume":"12","author":"Denko CW","year":"1985","journal-title":"J Rheumatol"},{"issue":"2","key":"CIT0088","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/j.1067-1927.2005.130207.x","volume":"13","author":"Poonawala T","year":"2005","journal-title":"Wound Repair Regen"},{"issue":"11","key":"CIT0089","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1016\/j.bcp.2009.03.003","volume":"77","author":"Rook JM","year":"2009","journal-title":"Biochem Pharmacol"},{"issue":"5","key":"CIT0090","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/j.bcp.2007.06.005","volume":"74","author":"Rook JM","year":"2007","journal-title":"Biochem Pharmacol"},{"issue":"6","key":"CIT0091","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1046\/j.1460-9568.1999.00625.x","volume":"11","author":"Binder W","year":"1999","journal-title":"Eur J Neurosci"},{"issue":"1","key":"CIT0092","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/S0022-3565(24)34907-9","volume":"290","author":"Machelska H","year":"1999","journal-title":"J Pharmacol Exp Ther"},{"issue":"6","key":"CIT0093","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1097\/00000542-200106000-00018","volume":"94","author":"Binder W","year":"2001","journal-title":"Anesthesiology"}],"container-title":["Expert Opinion on Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/14656566.2014.861818","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:07:36Z","timestamp":1746058056000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1517\/14656566.2014.861818"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,27]]},"references-count":93,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2013,11,11]]},"published-print":{"date-parts":[[2014,2]]}},"alternative-id":["10.1517\/14656566.2014.861818"],"URL":"https:\/\/doi.org\/10.1517\/14656566.2014.861818","relation":{},"ISSN":["1465-6566","1744-7666"],"issn-type":[{"value":"1465-6566","type":"print"},{"value":"1744-7666","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,27]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieop20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieop20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"}]}}