{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T12:17:25Z","timestamp":1774959445162,"version":"3.50.1"},"reference-count":82,"publisher":"Informa Healthcare","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Expert Opinion on Pharmacotherapy"],"published-print":{"date-parts":[[2005,10]]},"DOI":"10.1517\/14656566.6.12.2103","type":"journal-article","created":{"date-parts":[[2005,10,3]],"date-time":"2005-10-03T04:16:53Z","timestamp":1128313013000},"page":"2103-2115","source":"Crossref","is-referenced-by-count":32,"title":["Acamprosate in the treatment of alcohol dependence"],"prefix":"10.1517","volume":"6","author":[{"given":"Barbara J","family":"Mason","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3197","published-online":{"date-parts":[[2005,10,3]]},"reference":[{"issue":"3","key":"CIT0001","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.drugalcdep.2004.02.004","volume":"74","author":"GRANT BF","year":"2004","journal-title":"Drug Alcohol Depend."},{"issue":"2","key":"CIT0002","first-page":"177","volume":"30","author":"CAETANO R","year":"1995","journal-title":"Alcohol Alcohol."},{"issue":"18","key":"CIT0003","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.1001\/jama.1993.03510180077038","volume":"270","author":"MCGINNIS JM","year":"1993","journal-title":"JAMA"},{"issue":"19","key":"CIT0004","first-page":"2511","volume":"264","author":"REGIER DA","year":"1990","journal-title":"Results from the Epidemiologic Catchment Area (ECA) Study. JAMA"},{"issue":"14","key":"CIT0006","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1001\/jama.281.14.1318","volume":"281","author":"GARBUTT JC","year":"1999","journal-title":"JAMA"},{"issue":"9","key":"CIT0009","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1111\/j.1360-0443.1995.tb01088.x","volume":"90","author":"LITTLETON J","year":"1995","journal-title":"Addiction"},{"issue":"19","key":"CIT0011","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1056\/NEJM199905133401907","volume":"340","author":"SWIFT RM","year":"1999","journal-title":"N Engl. J. Med."},{"issue":"4","key":"CIT0013","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/0197-0186(94)00139-L","volume":"26","author":"NEVO I","year":"1995","journal-title":"Neurochem. Int."},{"issue":"5","key":"CIT0014","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/S0301-0082(98)00027-6","volume":"55","author":"FAINGOLD CL N&apos","year":"1998","journal-title":"Prog. Neurobiol"},{"issue":"1","key":"CIT0015","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1530-0277.1998.tb03611.x","volume":"22","author":"KOOB GF","year":"1998","journal-title":"Alcohol Clin. Exp. Res."},{"issue":"9013","key":"CIT0016","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1016\/S0140-6736(96)91682-7","volume":"347","author":"WHITWORTH AB","year":"1996","journal-title":"Lancet"},{"issue":"23","key":"CIT0017","doi-asserted-by":"crossref","first-page":"1840","DOI":"10.1001\/jama.1997.03540470022010","volume":"277","author":"O'BRIEN CP","year":"1997","journal-title":"JAMA"},{"issue":"15","key":"CIT0018","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1001\/jama.279.15.1227","volume":"279","author":"FRIEDMANN PD","year":"1998","journal-title":"JAMA"},{"issue":"12","key":"CIT0019","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1111\/j.1360-0443.1996.tb03801.x","volume":"91","author":"FINNEY JW","year":"1996","journal-title":"Addiction"},{"issue":"4","key":"CIT0020","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1111\/j.1360-0443.1997.tb03370.x","volume":"92","author":"HUGHES JC","year":"1997","journal-title":"Addiction"},{"issue":"5","key":"CIT0021","doi-asserted-by":"crossref","first-page":"427","DOI":"10.2165\/00002018-199920050-00003","volume":"20","author":"CHICK J","year":"1999","journal-title":"Drug Saf"},{"issue":"6","key":"CIT0022","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1093\/alcalc\/35.6.537","volume":"35","author":"KRANZLER HR","year":"2000","journal-title":"Alcohol Alcohol."},{"issue":"10","key":"CIT0023","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1001\/archpsyc.1992.01820110040006","volume":"49","author":"VOLPICELLI JR","year":"1992","journal-title":"Arch. Gen. Psychiatry"},{"issue":"11","key":"CIT0024","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1001\/archpsyc.1992.01820110045007","volume":"49","author":"O'MALLEY SS","year":"1992","journal-title":"A controlled study. Arch. Gen. Psychiatry"},{"issue":"9","key":"CIT0025","doi-asserted-by":"crossref","first-page":"547","DOI":"10.2165\/00023210-200418090-00001","volume":"18","author":"ROHSENOW DJ","year":"2004","journal-title":"CNS Drugs"},{"issue":"0","key":"CIT0027","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1093\/alcalc\/36.6.544","volume":"36","author":"STREETON C","year":"2001","journal-title":"Alcohol Alcohol."},{"issue":"9","key":"CIT0028","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1111\/j.1530-0277.2001.tb02356.x","volume":"25","author":"KRANZLER HR","year":"2001","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"24","key":"CIT0029","doi-asserted-by":"crossref","first-page":"1734","DOI":"10.1056\/NEJMoa011127","volume":"345","author":"KRYSTAL JH","year":"2001","journal-title":"N Engl J. Med."},{"issue":"8","key":"CIT0030","first-page":"1386","volume":"23","author":"MONTI PM","year":"1999","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"11","key":"CIT0033","first-page":"1413","volume":"39","author":"CHABENAT C","year":"1989","journal-title":"Arzneimittelforschung"},{"issue":"2","key":"CIT0034","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0378-4347(00)82333-6","volume":"530","author":"GIRAULT J","year":"1990","journal-title":"Chromatogr."},{"issue":"5","key":"CIT0035","doi-asserted-by":"crossref","first-page":"331","DOI":"10.2165\/00003088-199835050-00001","volume":"35","author":"SAIVIN S","year":"1998","journal-title":"Clin. Pharmacokinet."},{"issue":"0","key":"CIT0037","first-page":"1038","volume":"53","author":"WILDE MI","year":"1997","journal-title":"A review of its pharmacology and clinical potential in the management of alcohol dependence after detoxification. Drugs"},{"issue":"1","key":"CIT0038","doi-asserted-by":"crossref","first-page":"13","DOI":"10.2165\/00126839-200203010-00002","volume":"3","author":"NO AUTHORS LISTED]","year":"2002","journal-title":"Drugs R \u2022 D"},{"issue":"4","key":"CIT0041","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/S0893-133X(02)00368-8","volume":"27","author":"MASON BJ","year":"2002","journal-title":"Neuropsychopharmaco\/ogy"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.2165\/00023210-200519060-00004"},{"key":"CIT0044","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0074-7742(03)56002-0","volume":"56","author":"HOFFMAN PL","year":"2003","journal-title":"Int. Rev. NeurobioL"},{"key":"CIT0045","first-page":"152","volume":"54","author":"KUMARI M","year":"2000","journal-title":"Frog. Drug Res."},{"issue":"6","key":"CIT0046","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/S0028-3908(01)00008-9","volume":"40","author":"RAMMES G","year":"2001","journal-title":"Neuropharmaco\/ogy"},{"issue":"1","key":"CIT0047","first-page":"39","volume":"305","author":"SPANAGEL R","year":"1996","journal-title":"Effects on alcohol intake following alcohol deprivation in the rat. Eur. J. Pharmacol"},{"issue":"5","key":"CIT0048","first-page":"787","volume":"21","author":"BOISMARE F","year":"1984","journal-title":"Behav."},{"issue":"2","key":"CIT0049","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1093\/oxfordjournals.alcalc.a045093","volume":"26","author":"GEWISS M","year":"1991","journal-title":"Alcohol Alcohol."},{"issue":"2","key":"CIT0050","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0893-133X(97)00130-9","volume":"18","author":"HEYSER CJ","year":"1998","journal-title":"Neuropsychopharmacology"},{"issue":"2","key":"CIT0051","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0741-8329(87)90005-X","volume":"4","author":"LE MAGNEN J","year":"1987","journal-title":"Alcohol"},{"issue":"4","key":"CIT0052","first-page":"802","volume":"22","author":"NAASSILA M","year":"1998","journal-title":"Part I. Characterization of spermidine-sensitive acamprosate binding site in rat brain. Alcohol. Clin. Exp. Res."},{"issue":"1","key":"CIT0053","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0014-2999(93)90682-8","volume":"231","author":"ZEISE ML","year":"1993","journal-title":"Eur. J. Pharmacol."},{"issue":"1","key":"CIT0054","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0014-2999(95)00344-K","volume":"283","author":"ROSSETTI ZL","year":"1995","journal-title":"Eur. j Pharmacol."},{"issue":"2","key":"CIT0055","first-page":"107","volume":"82","author":"DAHCHOUR A","year":"1998","journal-title":"Acamprosate blocks the glutamate increase in the nucleus accumbens microdialysate in ethanol withdrawn rats. Psychiatry Res."},{"issue":"4","key":"CIT0056","first-page":"810","volume":"22","author":"AL QATARI M","year":"1998","journal-title":"Ethanol dependence modifies effects of acamprosate on NMDA receptor binding in membranes from rat cerebral cortex. Alcohol. Clin. Exp. Res."},{"issue":"5","key":"CIT0057","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1111\/j.1530-0277.2002.tb02587.x","volume":"26","author":"MAYER S","year":"2002","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"2","key":"CIT0058","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0014-2999(00)00195-3","volume":"394","author":"POPP RL","year":"2000","journal-title":"Eur. j Pharmacol."},{"issue":"11","key":"CIT0059","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1097\/01.ALC.0000093601.33119.E3","volume":"27","author":"HARRIS BR","year":"2003","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"CIT0061","unstructured":"HARRIS BR, FERCHMIN PA, BLANCHARD JA et al.: The sodium salt of acamprosate inhibits the potentiation of NMDA responses by a selective mGluR5 agonist (Abstr.). Proceedings of the 27th Annual Research Society on Alcoholism Scientific Meeting, Vancouver, Canada (2004)."},{"key":"CIT0062","first-page":"73","volume":"171","author":"PELC I","year":"1997","journal-title":"A 90-day placebo-controlled dose-finding study. Br. J. Psychiatry"},{"issue":"8","key":"CIT0064","first-page":"673","volume":"53","author":"SASS H","year":"1996","journal-title":"Results from a placebo-controlled study on alcohol dependence. Arch. Gen. Psychiatry"},{"issue":"2","key":"CIT0066","first-page":"239","volume":"30","author":"PAILLE FM","year":"1995","journal-title":"Alcohol Alcohol."},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(85)91615-0"},{"issue":"6","key":"CIT0069","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1093\/oxfordjournals.alcalc.a045057","volume":"25","author":"LHUINTRE JP","year":"1990","journal-title":"Alcohol Alcohol."},{"key":"CIT0070","first-page":"65","volume":"51","author":"ROUSSAUX JP","year":"1996","journal-title":"Belg."},{"issue":"3","key":"CIT0072","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1590\/S1516-44462003000300007","volume":"25","author":"BALTIERI DA","year":"2003","journal-title":"Rev. Bras. Psiquiatr."},{"key":"CIT0073","first-page":"149","volume":"18","author":"BARRIAS JA","year":"1997","journal-title":"Psiqiatria Clinica"},{"issue":"3","key":"CIT0074","first-page":"573","volume":"22","author":"BESSON J","year":"1998","journal-title":"LEHERT P, POTGIETER A: Combined efficacy of acamprosate and disulfiram in the treatment of alcoholism: a controlled study. Alcohol. Clin. Exp. Res."},{"issue":"11","key":"CIT0075","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1111\/j.1360-0443.1997.tb02873.x","volume":"92","author":"POLDRUGO F","year":"1997","journal-title":"Addiction"},{"issue":"2","key":"CIT0076","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1093\/alcalc\/35.2.202","volume":"35","author":"TEMPESTA E","year":"2000","journal-title":"Alcohol Alcohol."},{"issue":"2","key":"CIT0077","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1093\/alcalc\/35.2.176","volume":"35","author":"CHICK J","year":"2000","journal-title":"Alcohol Alcohol."},{"issue":"3","key":"CIT0078","first-page":"129","volume":"3","author":"GEERLINGS PJ","year":"1997","journal-title":"Results of a randomized, placebo-controlled, double-blind study in out-patients in the Netherlands, Belgium and Luxembourg. Eur. Addict. Res."},{"issue":"5","key":"CIT0079","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1093\/alcalc\/36.5.413","volume":"36","author":"GUAL A","year":"2001","journal-title":"Alcohol Alcohol."},{"issue":"3","key":"CIT0080","first-page":"182","volume":"50","author":"LADEWIG D","year":"1993","journal-title":"Ther. Umsch."},{"issue":"1","key":"CIT0082","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1001\/archpsyc.60.1.92","volume":"60","author":"KIEFER F","year":"2003","journal-title":"Arch. Gen. Psychiatry"},{"issue":"8","key":"CIT0084","doi-asserted-by":"crossref","first-page":"485","DOI":"10.2165\/00023210-200418080-00002","volume":"18","author":"MANN K","year":"2004","journal-title":"CNS Drugs"},{"issue":"1","key":"CIT0085","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1097\/01.ALC.0000108656.81563.05","volume":"28","author":"MANN K","year":"2004","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"7","key":"CIT0086","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1111\/j.1360-0443.2004.00763.x","volume":"99","author":"BOUZA C","year":"2004","journal-title":"Addiction"},{"key":"CIT0087","first-page":"130A","volume":"26","author":"HOPKINS JS","year":"2002","journal-title":"Alcohol Clin. Exp. Res."},{"key":"CIT0088","doi-asserted-by":"crossref","first-page":"160A","DOI":"10.1097\/01.alc.0000179409.80370.25","volume":"29","author":"SCHNEIDER E","year":"2005","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"5","key":"CIT0090","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1046\/j.1440-1614.2002.01019.x","volume":"36","author":"FEENEY GF","year":"2002","journal-title":"N Z. J. Psychiatry"},{"issue":"3","key":"CIT0091","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1093\/alcalc\/agh056","volume":"39","author":"HAMMARBERG A.","year":"2004","journal-title":"Alcohol Alcohol."},{"issue":"1","key":"CIT0092","first-page":"1","volume":"3","author":"SOYKA M","year":"2002","journal-title":"Results from a non-blind, multicentre study. Drugs R ebD"},{"issue":"10","key":"CIT0093","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1111\/j.1530-0277.2002.tb02452.x","volume":"26","author":"PELC I","year":"2002","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"7","key":"CIT0096","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1111\/j.1530-0277.2003.tb02873.x","volume":"27","author":"COMBINE STUDY RESEARCH GROUP","year":"2003","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"1","key":"CIT0100","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/j.1440-1819.2004.01189.x","volume":"58","author":"KIM SG","year":"2004","journal-title":"Psychiatry Clin. Neurosci."},{"issue":"6","key":"CIT0102","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.euroneuro.2003.08.009","volume":"13","author":"MASON BJ","year":"2003","journal-title":"Eur. Neuropsychopharmacol"},{"issue":"3","key":"CIT0103","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/0091-3057(89)90005-1","volume":"32","author":"GRANT KA","year":"1989","journal-title":"Pharmacol Biochem. Behav."},{"issue":"6","key":"CIT0105","first-page":"719","volume":"13","author":"SCHADLICH PK","year":"1998","journal-title":"Economic evaluation of the Prevention of Relapse with Acamprosate in the Management of Alcoholism (PRAMA) Study. Pharmacoeconomics"},{"issue":"5","key":"CIT0106","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1093\/alcalc\/35.5.478","volume":"35","author":"PALMER AJ","year":"2000","journal-title":"Alcohol Alcohol."},{"issue":"2","key":"CIT0107","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1159\/000019013","volume":"6","author":"ANNEMANS L","year":"2000","journal-title":"Eur. Addict. Res."},{"issue":"2","key":"CIT0108","first-page":"59","volume":"9","author":"RYCHLIK R","year":"2003","journal-title":"Ent: Addict. Res."},{"key":"CIT0109","doi-asserted-by":"crossref","first-page":"172A","DOI":"10.1097\/01.alc.0000189278.30237.e9","volume":"29","author":"ERDER MH","year":"2005","journal-title":"Alcohol. Clin. Exp. Res."}],"container-title":["Expert Opinion on Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/14656566.6.12.2103","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,3,26]],"date-time":"2019-03-26T13:28:33Z","timestamp":1553606913000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1517\/14656566.6.12.2103"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,10]]},"references-count":82,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2005,10,3]]},"published-print":{"date-parts":[[2005,10]]}},"alternative-id":["10.1517\/14656566.6.12.2103"],"URL":"https:\/\/doi.org\/10.1517\/14656566.6.12.2103","relation":{},"ISSN":["1465-6566","1744-7666"],"issn-type":[{"value":"1465-6566","type":"print"},{"value":"1744-7666","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,10]]}}}