{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T21:18:35Z","timestamp":1790889515933,"version":"4.1.0"},"reference-count":76,"publisher":"Informa Healthcare","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Expert Opinion on Pharmacotherapy"],"published-print":{"date-parts":[[2007,7]]},"DOI":"10.1517\/14656566.8.10.1441","type":"journal-article","created":{"date-parts":[[2007,7,30]],"date-time":"2007-07-30T11:33:18Z","timestamp":1185795198000},"page":"1441-1449","source":"Crossref","is-referenced-by-count":47,"title":["Multidrug resistance in epilepsy: a pharmacogenomic update"],"prefix":"10.1517","volume":"8","author":[{"given":"Sarah K","family":"Tate","sequence":"first","affiliation":[{"name":"University College London, Department of Clinical and Experimental Epilepsy, Institute of Neurology, Queen Square, London WC1N 3BG, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay M","family":"Sisodiya","sequence":"additional","affiliation":[{"name":"University College London, Department of Clinical and Experimental Epilepsy, Institute of Neurology, Queen Square, London WC1N 3BG"},{"name":"National Society for Epilepsy, Chalfont-St-Peter, Bucks, SL9 0RJ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3197","published-online":{"date-parts":[[2007,7,30]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2005.54904.x"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1111\/j.0013-9580.2005.31904.x"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh682"},{"key":"CIT0004","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S0887-8994(99)00031-4","volume":"21","author":"SILLANPAA","year":"1999","journal-title":"Pediatr. Neurol."},{"key":"CIT0005","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1212\/WNL.51.5.1256","volume":"51","author":"SEMAH","year":"1998","journal-title":"Neurology"},{"key":"CIT0006","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1111\/j.1528-1167.2006.00440.x","volume":"47","author":"BERG","year":"2006","journal-title":"Epilepsia"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1002\/ana.10473"},{"key":"CIT0008","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0920-1211(98)00061-8","volume":"32","author":"VREUGDENHIL","year":"1998","journal-title":"Epilepsy Res."},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.103.049858"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1124\/mol.61.4.729"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2202-6-61"},{"key":"CIT0012","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.eplepsyres.2005.12.005","volume":"69","author":"HOFFMANN","year":"2006","journal-title":"Epilepsy Res."},{"key":"CIT0013","first-page":"311","volume":"49","author":"SCHUETZ","year":"1996","journal-title":"Mol. Pharmacol."},{"key":"CIT0014","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/j.1365-2125.2006.02587.x","volume":"62","author":"OWEN","year":"2006","journal-title":"Br. J. Clin. Pharmacol."},{"key":"CIT0015","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1111\/j.1528-1167.2005.00250.x","volume":"46","author":"VAN","year":"2005","journal-title":"Epilepsia"},{"key":"CIT0016","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/j.1365-2990.2005.00699.x","volume":"32","author":"SISODIYA","year":"2006","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"CIT0017","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1111\/j.1528-1167.2005.00265.x","volume":"46","author":"MARCHI","year":"2005","journal-title":"Epilepsia"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2006.00504.x"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(94)90212-7"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118699"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1046\/j.1528-1157.2001.01901.x"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200111160-00037"},{"key":"CIT0023","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/S1525-5050(02)00511-5","volume":"3","author":"SILLS","year":"2002","journal-title":"Epilepsy Behav."},{"key":"CIT0024","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.nbd.2006.06.014","volume":"24","author":"BRANDT","year":"2006","journal-title":"Neurobiol. Dis."},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2125.2001.01359.x"},{"key":"CIT0026","author":"BALTES","year":"2006","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1080\/10611860600720814"},{"key":"CIT0028","author":"BALTES","year":"2006","journal-title":"Neuropharmacology"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1097\/00019052-200304000-00013"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa021986"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.050585397"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1097\/00008571-200106000-00003"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)07276-8"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2125.2002.01591.x"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1067\/mcp.2001.117412"},{"key":"CIT0037","author":"LESCHZINER","year":"2006","journal-title":"Pharmacogenomics J."},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1126\/science.1135308"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1038\/nrg1229"},{"key":"CIT0040","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1517\/14622416.6.4.411","volume":"6","author":"HUNG","year":"2005","journal-title":"Pharmacogenomics"},{"key":"CIT0041","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1212\/01.WNL.0000141021.42763.F6","volume":"63","author":"ZIMPRICH","year":"2004","journal-title":"Neurology"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000137051.33486.C7"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2005.46304.x"},{"key":"CIT0044","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.seizure.2006.02.015","volume":"15","author":"KIM","year":"2006","journal-title":"Seizure"},{"key":"CIT0045","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/S1474-4422(06)70500-2","volume":"5","author":"LESCHZINER","year":"2006","journal-title":"Lancet Neurol."},{"key":"CIT0046","author":"BALTES","year":"2006","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.2217\/14622416.7.4.551"},{"key":"CIT0048","author":"SHAHWAN","journal-title":"Epilepsy Res."},{"key":"CIT0049","doi-asserted-by":"crossref","first-page":"8312","DOI":"10.1523\/JNEUROSCI.19-19-08312.1999","volume":"19","author":"BROOKS-Kayal","year":"1999","journal-title":"J. Neurosci."},{"key":"CIT0050","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1046\/j.1471-4159.1998.70031017.x","volume":"70","author":"BROOKS-KAYAL","year":"1998","journal-title":"J. Neurochem."},{"key":"CIT0051","doi-asserted-by":"crossref","first-page":"6826","DOI":"10.1523\/JNEUROSCI.23-17-06826.2003","volume":"23","author":"BENDER","year":"2003","journal-title":"J. Neurosci."},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-06-2111"},{"key":"CIT0053","doi-asserted-by":"crossref","first-page":"5507","DOI":"10.1073\/pnas.0407346102","volume":"102","author":"TATE","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"CIT0054","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1097\/01.fpc.0000230114.41828.73","volume":"16","author":"TATE","year":"2006","journal-title":"Pharmacogenet. Genomics"},{"key":"CIT0055","doi-asserted-by":"crossref","first-page":"R32","DOI":"10.1186\/gb-2007-8-3-r32","volume":"8","author":"HEINZEN","year":"2007","journal-title":"Genome Biol."},{"key":"CIT0056","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1016\/S0140-6736(06)68477-8","volume":"367","author":"DUNCAN","year":"2006","journal-title":"Lancet"},{"key":"CIT0057","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/j.1528-1167.2005.00350.x","volume":"10","author":"OTTMAN","year":"2005","journal-title":"Epilepsia"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1126\/science.1109557"},{"key":"CIT0059","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1038\/ng1047","volume":"32","author":"OZAKI","year":"2002","journal-title":"Nat. Genet."},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1086\/496902"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1038\/ng1999"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1038\/ng2022"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1038\/nature05616"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1126\/science.1142382"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1126\/science.1142358"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1038\/ng2043"},{"key":"CIT0067","author":"BAUM","year":"2007","journal-title":"Mol. Psychiatry"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1126\/science.1135245"},{"key":"CIT0069","doi-asserted-by":"crossref","first-page":"e58","DOI":"10.1371\/journal.pgen.0030058","volume":"3","author":"LIBIOULLE","year":"2007","journal-title":"PLoS Genet."},{"key":"CIT0070","author":"EASTON","year":"2007","journal-title":"Nature"},{"key":"CIT0071","author":"HUNTER","year":"2007","journal-title":"Nat. Genet."},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1038\/nature05911"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1038\/nature05329"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1126\/science.1136678"},{"key":"CIT0075","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1038\/nature04489","volume":"439","author":"AITMAN","year":"2006","journal-title":"Nature"},{"key":"CIT0076","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1212\/01.WNL.0000031792.89992.EC","volume":"60","author":"BERG","year":"2003","journal-title":"Neurology"},{"key":"CIT0077","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1124\/jpet.103.054197","volume":"307","author":"WEISS","year":"2003","journal-title":"J. Pharmacol. Exp. Ther."}],"container-title":["Expert Opinion on Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/14656566.8.10.1441","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,9,10]],"date-time":"2018-09-10T14:20:55Z","timestamp":1536589255000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1517\/14656566.8.10.1441"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7]]},"references-count":76,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2007,7,30]]},"published-print":{"date-parts":[[2007,7]]}},"alternative-id":["10.1517\/14656566.8.10.1441"],"URL":"https:\/\/doi.org\/10.1517\/14656566.8.10.1441","relation":{},"ISSN":["1465-6566","1744-7666"],"issn-type":[{"value":"1465-6566","type":"print"},{"value":"1744-7666","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,7]]}}}