{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:08:45Z","timestamp":1762430925657},"reference-count":146,"publisher":"Informa Healthcare","issue":"2","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Biological Therapy"],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.1517\/14712598.2015.978853","type":"journal-article","created":{"date-parts":[[2014,11,12]],"date-time":"2014-11-12T11:33:39Z","timestamp":1415792019000},"page":"213-230","update-policy":"http:\/\/dx.doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":13,"title":["Treatment of multiple myeloma bone disease: experimental and clinical data"],"prefix":"10.1517","volume":"15","author":[{"given":"Yvonne Mary","family":"Papamerkouriou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eustathios","family":"Kenanidis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zakareya","family":"Gamie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyriakos","family":"Papavasiliou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Kostakos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Potoupnis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioannis","family":"Sarris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleftherios","family":"Tsiridis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Kyrkos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3197","published-online":{"date-parts":[[2014,11,12]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2001.03206.x"},{"key":"CIT0002","volume-title":"IARC CancerBase No 4","author":"Ferlay JBF","year":"1999"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.48.1.31"},{"key":"CIT0004","volume-title":"SEER Cancer Statistics Review, 1975-2004","author":"Ries L","year":"2007"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.4065\/78.1.21"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.12-1-62"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1586\/17474086.2014.882763"},{"key":"CIT0008","first-page":"SP140","volume":"18","author":"Mohundro MM","year":"2012","journal-title":"Am J Manag Care"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1200\/EdBook_AM.2013.33.e307"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-014-0276-6"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.2014.889681"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1586\/14737140.2014.884930"},{"key":"CIT0013","first-page":"190","volume":"1","author":"Palumbo A","year":"2011","journal-title":"Am J Blood Res"},{"key":"CIT0014","author":"Lopuch S","year":"2014","journal-title":"Hematology (Am Soc Hematol Educ Program)"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2011.1.184"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2007.04.022"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1172\/JCI115305"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdi235"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1586\/ehm.09.36"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1999.01193.x"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-12-3905"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2005.12.025"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-1687"},{"key":"CIT0024","doi-asserted-by":"crossref","first-page":"3998","DOI":"10.1182\/blood.V88.10.3998.bloodjournal88103998","volume":"88","author":"Borset M","year":"1996","journal-title":"Blood"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-06-1992"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-04-279760"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1007\/s12307-011-0090-7"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2011.282"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1007\/s11899-012-0135-0"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1358\/dot.2004.40.1.799436"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1016\/8756-3282(95)00445-9"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1210\/er.19.1.80"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.1997.12.6.869"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1124\/mol.105.020776"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.2174\/1381612033453640"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-06-0843"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.2009.00160.x"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1402.089"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2404843"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.47.7901"},{"key":"CIT0041","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1200\/JCO.1991.9.8.1397","volume":"9","author":"Belch AR","year":"1991","journal-title":"J Clin Oncol"},{"key":"CIT0042","first-page":"449","volume":"2","author":"Daragon A","year":"1993","journal-title":"Eur J Med"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2002.02.032"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2010-0225"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)93075-X"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1998.00567.x"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1998.00695.x"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199602223340802"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20010401)91:7<1191::AID-CNCR1119>3.0.CO;2-0"},{"key":"CIT0050","first-page":"377","volume":"7","author":"Rosen LS","year":"2001","journal-title":"Cancer J"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(11)70157-7"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-11-392522"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2003.18.3.482"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdn796"},{"key":"CIT0055","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1200\/JCO.1998.16.2.593","volume":"16","author":"Berenson JR","year":"1998","journal-title":"J Clin Oncol"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/842945"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2007.01.022"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2003.04473.x"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.4065\/81.7.889"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2403890"},{"key":"CIT0061","first-page":"133","volume":"91","author":"Offidani M","year":"2006","journal-title":"Haematologica"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2005.00610.x"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2011.044271"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1111\/j.0902-4441.2005.t01-1-EJH2520.x"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1136\/ard.58.2008.i107"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2008.174"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1016\/0162-3109(95)00050-X"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdl313"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-10-184135"},{"key":"CIT0070","first-page":"1260","volume":"116","author":"Reece DE M-KE","year":"2009","journal-title":"BLOOD"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.19.8424"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2010.08250.x"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa070594"},{"key":"CIT0074","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1182\/blood.V110.11.412.412","volume":"110","author":"Weber DKR","year":"2007","journal-title":"Blood"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2009.147"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-08-239046"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.23577"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(13)70380-2"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2014.60"},{"key":"CIT0080","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-014-0196-6"},{"key":"CIT0081","first-page":"2615","volume":"59","author":"Adams J","year":"1999","journal-title":"Cancer Res"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1361"},{"key":"CIT0083","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-3684"},{"key":"CIT0084","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-006-0220-3"},{"key":"CIT0085","doi-asserted-by":"crossref","first-page":"2767","DOI":"10.1182\/blood-2006-08-042275","volume":"109","author":"Palumbo A","year":"2007","journal-title":"Blood"},{"key":"CIT0086","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2008.99"},{"key":"CIT0087","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.14.2372"},{"key":"CIT0088","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2008.07572.x"},{"key":"CIT0089","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2011.08949.x"},{"key":"CIT0090","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2404806"},{"key":"CIT0091","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2006.06356.x"},{"key":"CIT0092","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2005.05733.x"},{"key":"CIT0093","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-11-059188"},{"key":"CIT0094","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2006.00692.x"},{"key":"CIT0095","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdq259"},{"key":"CIT0096","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2011.01599.x"},{"key":"CIT0097","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.12279"},{"key":"CIT0098","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2012.183"},{"key":"CIT0099","first-page":"B4277","volume":"58","author":"Kupisiewicz K","year":"2011","journal-title":"Dan Med Bull"},{"key":"CIT0100","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2011.08573.x"},{"key":"CIT0101","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2014.896460"},{"key":"CIT0102","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2013.100396"},{"key":"CIT0103","first-page":"308","volume":"17","author":"Roodman GD","year":"1996","journal-title":"Endocr Rev"},{"key":"CIT0104","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2004.05143.x"},{"key":"CIT0105","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2000.15.9.1766"},{"key":"CIT0106","doi-asserted-by":"publisher","DOI":"10.1038\/16852"},{"key":"CIT0107","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20010801)92:3<460::AID-CNCR1344>3.0.CO;2-D"},{"key":"CIT0108","doi-asserted-by":"publisher","DOI":"10.1210\/en.2007-1719"},{"key":"CIT0109","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.201394498"},{"key":"CIT0110","first-page":"275","volume":"90","author":"Giuliani N","year":"2005","journal-title":"Haematologica"},{"key":"CIT0111","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-01-132134"},{"key":"CIT0112","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2002.03257.x"},{"key":"CIT0113","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11138"},{"key":"CIT0114","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-05-1933"},{"key":"CIT0115","first-page":"509","volume":"182","author":"Fizazi KLA","year":"2008","journal-title":"Phase II study.J Clin Oncol"},{"issue":"1","key":"CIT0116","first-page":"1054A","volume":"110","author":"Vij RHN","year":"2007","journal-title":"Blood"},{"key":"CIT0117","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.31.3304"},{"key":"CIT0118","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.2000.2075"},{"key":"CIT0119","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.10613"},{"key":"CIT0120","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0911929107"},{"key":"CIT0121","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.142"},{"key":"CIT0122","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.081208"},{"key":"CIT0123","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12835"},{"key":"CIT0124","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2013.50"},{"key":"CIT0125","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2013.08.002"},{"key":"CIT0126","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.22033"},{"key":"CIT0127","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-11-191577"},{"issue":"21","key":"CIT0128","first-page":"331","volume":"120","author":"Munshi NC AR","year":"2012","journal-title":"Blood abstract meeting book ASH"},{"key":"CIT0129","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2189"},{"key":"CIT0130","doi-asserted-by":"crossref","first-page":"989a","DOI":"10.1182\/blood.V108.11.989.989","volume":"108","author":"Breitkreutz IVS","year":"2006","journal-title":"Blood"},{"key":"CIT0131","doi-asserted-by":"crossref","first-page":"153a","DOI":"10.1182\/blood.V108.11.153.153","volume":"108","author":"Feng R","year":"2006","journal-title":"Blood"},{"issue":"11","key":"CIT0132","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1182\/blood.V110.11.1179.1179","volume":"110","author":"Richardson PG","year":"2007","journal-title":"Blood"},{"key":"CIT0134","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2009.04.022"},{"key":"CIT0135","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2001.16.10.1787"},{"key":"CIT0136","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7600067"},{"key":"CIT0137","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(01)00580-4"},{"key":"CIT0138","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/20.9.2254"},{"key":"CIT0139","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.5650050109"},{"key":"CIT0140","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000093055.96273.69"},{"key":"CIT0141","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0009870"},{"key":"CIT0142","doi-asserted-by":"publisher","DOI":"10.1007\/s12185-008-0226-9"},{"key":"CIT0143","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0046287"},{"key":"CIT0144","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.26059"},{"key":"CIT0145","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2013.07.024"},{"key":"CIT0146","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.37.2649"},{"key":"CIT0147","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2010.030759"}],"container-title":["Expert Opinion on Biological Therapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/14712598.2015.978853","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,26]],"date-time":"2020-08-26T18:20:51Z","timestamp":1598466051000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1517\/14712598.2015.978853"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,12]]},"references-count":146,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2014,10,15]]},"published-print":{"date-parts":[[2015,2]]}},"alternative-id":["10.1517\/14712598.2015.978853"],"URL":"https:\/\/doi.org\/10.1517\/14712598.2015.978853","relation":{},"ISSN":["1471-2598","1744-7682"],"issn-type":[{"value":"1471-2598","type":"print"},{"value":"1744-7682","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,12]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iebt20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iebt20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"}]}}