{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T01:44:14Z","timestamp":1786585454067,"version":"build-2736575974"},"reference-count":151,"publisher":"Informa UK Limited","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Expert Opinion on Biological Therapy"],"published-print":{"date-parts":[[2004,3]]},"DOI":"10.1517\/14712598.4.3.279","type":"journal-article","created":{"date-parts":[[2005,5,4]],"date-time":"2005-05-04T15:57:22Z","timestamp":1115222242000},"page":"279-299","source":"Crossref","is-referenced-by-count":19,"title":["Cytokine therapy for craniosynostosis"],"prefix":"10.1517","volume":"4","author":[{"given":"Mark P","family":"Mooney","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amr M","family":"Moursi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynne A","family":"Opperman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael I","family":"Siegel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2005,3,3]]},"reference":[{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320470507"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1159\/000120913"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1097\/00001665-199903000-00003"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569(2000)037<0370:ARCIIP>2.3.CO;2"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199209000-00003"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1159\/000121038"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569(1998)035<0167:MSSAII>2.3.CO;2"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199710000-00005"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1097\/00001665-199805000-00010"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-199206000-00008"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199392050-00008"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1995.83.3.0476"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569(2003)040<0486:ENBICR>2.0.CO;2"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000056839.94034.47"},{"key":"CIT0035","first-page":"284","volume":"96","author":"MCCARTHY JG","year":"1995","journal-title":"I. Isolated craniofacial synostosis: results and unsolved problems. Plast. Reconstr. Surg."},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2001.42.6.646"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1974.41.6.0715"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-199010000-00006"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1097\/00001665-199211000-00009"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1097\/00001665-199304000-00006"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1054\/bjps.2002.3923"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569(2001)038<0533:TFOACS>2.0.CO;2"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1159\/000028706"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569(2001)038<0206:COCSSU>2.0.CO;2"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1097\/00001665-200303000-00003"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199708000-00003"},{"key":"CIT0052","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S0094-1298(20)32662-6","volume":"26","author":"BOYAN BD","year":"1999","journal-title":"Clin. Plast. Surg."},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.192291499"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1177\/10454411010120010501"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1097\/00019052-199604000-00016"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199702000-00002"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1038\/nature01545"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1002\/ar.a.10113"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-1004(1999)14:2<115::AID-HUMU3>3.0.CO;2-2"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1038\/ng0994-98"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(95)00102-3"},{"key":"CIT0069","first-page":"321","volume":"57","author":"PARK WJ","year":"1995","journal-title":"Am. J. Hum. Genet."},{"key":"CIT0070","first-page":"555","volume":"60","author":"MUENKE M","year":"1997","journal-title":"Am. J. Hum. Genet."},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1086\/301855"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1172\/JCI12853"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.5650071004"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90379-5"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/5.12.1915"},{"key":"CIT0076","first-page":"305","volume":"64","author":"HALL BK","year":"1981","journal-title":"J. Embryo]. Exp. Morph."},{"key":"CIT0077","first-page":"107","volume":"186","author":"HALL BK","year":"1992","journal-title":"Anat. Embryo]."},{"key":"CIT0078","first-page":"881","volume":"39","author":"HALL BK","year":"1995","journal-title":"Int. J. Dev. Biol."},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-1878(200002)22:2<138::AID-BIES5>3.0.CO;2-4"},{"key":"CIT0081","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.2001.0487"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001980408"},{"key":"CIT0083","doi-asserted-by":"publisher","DOI":"10.1097\/00001665-199411000-00012"},{"key":"CIT0084","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.5650101218"},{"key":"CIT0085","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199604000-00001"},{"key":"CIT0086","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1242\/dev.125.7.1241","volume":"125","author":"KIM HJ","year":"1998","journal-title":"Development"},{"key":"CIT0087","first-page":"627","volume":"32","author":"OPPERMAN LA","year":"1996","journal-title":"NOLAN AA eta].: Dura mater secretes soluble heparin-binding factors required for cranial suture morphogenesis. In Vitro Cell. Dev. Biol."},{"key":"CIT0088","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.13.6137"},{"key":"CIT0089","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.1997.12.3.301"},{"key":"CIT0090","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199811000-00001"},{"key":"CIT0091","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199907000-00019"},{"key":"CIT0092","first-page":"352","volume":"15","author":"GRAVE B","year":"2000","journal-title":"Ann. Royal Australasian Coll Dent. Surg."},{"key":"CIT0093","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0544.2002.02227.x"},{"key":"CIT0094","doi-asserted-by":"publisher","DOI":"10.1006\/cyto.2002.0877"},{"key":"CIT0095","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4773(01)00656-6"},{"key":"CIT0096","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1242\/dev.127.9.1845","volume":"127","author":"RICE DP","year":"2000","journal-title":"Development"},{"key":"CIT0097","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199805000-00001"},{"key":"CIT0098","doi-asserted-by":"publisher","DOI":"10.1046\/j.0909-8836.1999.eos107406.x"},{"key":"CIT0099","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199601000-00001"},{"key":"CIT0100","doi-asserted-by":"crossref","first-page":"5611","DOI":"10.1242\/dev.126.24.5611","volume":"126","author":"ISEKI S","year":"1999","journal-title":"Development"},{"key":"CIT0101","doi-asserted-by":"crossref","first-page":"3375","DOI":"10.1242\/dev.124.17.3375","volume":"124","author":"ISEKI S","year":"1997","journal-title":"Development"},{"key":"CIT0102","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4773(99)00278-6"},{"key":"CIT0103","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-199905000-00007"},{"key":"CIT0104","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0544.2002.01179.x"},{"key":"CIT0105","doi-asserted-by":"publisher","DOI":"10.1002\/ar.10094"},{"key":"CIT0106","doi-asserted-by":"publisher","DOI":"10.1038\/74231"},{"key":"CIT0107","first-page":"260","volume":"205","author":"LIU YH","year":"1999","journal-title":"Dev."},{"key":"CIT0108","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80258-5"},{"key":"CIT0109","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80259-7"},{"key":"CIT0110","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/9.13.2001"},{"key":"CIT0111","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/7.9.1475"},{"key":"CIT0112","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569(2002)039<0487:FGFIIC>2.0.CO;2"},{"key":"CIT0113","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.10319"},{"key":"CIT0115","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0177(199806)212:2<242::AID-AJA8>3.0.CO;2-H"},{"key":"CIT0116","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.6.12.1861"},{"key":"CIT0117","doi-asserted-by":"publisher","DOI":"10.1172\/JCI119886"},{"key":"CIT0118","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2001.16.5.832"},{"key":"CIT0119","doi-asserted-by":"publisher","DOI":"10.1002\/0470846658.ch8"},{"key":"CIT0120","doi-asserted-by":"publisher","DOI":"10.1172\/JCI11846"},{"key":"CIT0121","doi-asserted-by":"crossref","first-page":"3783","DOI":"10.1242\/dev.129.16.3783","volume":"129","author":"ESWARAKUMAR VP","year":"2002","journal-title":"Development"},{"key":"CIT0123","doi-asserted-by":"publisher","DOI":"10.1016\/S0012-1606(03)00059-9"},{"key":"CIT0124","doi-asserted-by":"publisher","DOI":"10.1097\/00001665-200107000-00019"},{"key":"CIT0125","first-page":"127","volume":"20","author":"MATHUSSEN IM","year":"2000","journal-title":"j Craniofac. Genet. Dev. Biol."},{"key":"CIT0126","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000070729.05978.BB"},{"key":"CIT0127","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200202000-00035"},{"key":"CIT0128","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)65401-6"},{"key":"CIT0129","doi-asserted-by":"publisher","DOI":"10.1006\/excr.2000.4820"},{"key":"CIT0130","first-page":"329a","volume":"8","author":"OPPERMAN LA","year":"1997","journal-title":"Ma Biol. Cell"},{"key":"CIT0131","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0177(2000)9999:9999<::AID-DVDY1044>3.0.CO;2-F"},{"key":"CIT0132","first-page":"164","volume":"19","author":"OPPERMAN LA","year":"1999","journal-title":"1. Craniofac. Genet. Dev. Biol."},{"key":"CIT0133","first-page":"150","volume":"18","author":"OPPERMAN LA","year":"1998","journal-title":"J. Craniofac. Genet. Dev. Biol."},{"key":"CIT0134","doi-asserted-by":"crossref","first-page":"20533","DOI":"10.1016\/S0021-9258(17)30535-5","volume":"265","author":"CHEIFEZ S","year":"1990","journal-title":"Biol. Chem"},{"key":"CIT0135","doi-asserted-by":"publisher","DOI":"10.1101\/SQB.1997.062.01.021"},{"key":"CIT0136","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1242\/dev.126.6.1189","volume":"126","author":"MARTINEZ S","year":"1999","journal-title":"Development"},{"key":"CIT0137","doi-asserted-by":"publisher","DOI":"10.1126\/science.285.5426.403"},{"key":"CIT0138","doi-asserted-by":"publisher","DOI":"10.1101\/gad.13.23.3136"},{"key":"CIT0139","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0177(199712)210:4<383::AID-AJA3>3.0.CO;2-C"},{"key":"CIT0140","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1242\/dev.125.2.161","volume":"125","author":"JERNVALL J","year":"1998","journal-title":"Development"},{"key":"CIT0141","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(99)00119-2"},{"key":"CIT0142","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.1995.1300"},{"key":"CIT0143","doi-asserted-by":"publisher","DOI":"10.1007\/s004410051270"},{"key":"CIT0144","doi-asserted-by":"publisher","DOI":"10.1101\/gad.12.11.1571"},{"key":"CIT0145","doi-asserted-by":"publisher","DOI":"10.1038\/75644"},{"key":"CIT0147","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.27.16422"},{"key":"CIT0148","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/9.5.813"},{"key":"CIT0149","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(01)02238-4"},{"key":"CIT0150","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(02)02260-X"},{"key":"CIT0151","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/11.4.359"},{"key":"CIT0152","first-page":"139","volume":"25","author":"RICE DP","year":"2003","journal-title":"Lim J Orthod"},{"key":"CIT0153","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0177(2000)9999:9999<::AID-DVDY1074>3.0.CO;2-C"},{"key":"CIT0154","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80260-3"},{"key":"CIT0155","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/8.12.2311"},{"key":"CIT0156","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.180309597"},{"key":"CIT0157","doi-asserted-by":"publisher","DOI":"10.3109\/08977199308991582"},{"key":"CIT0158","doi-asserted-by":"publisher","DOI":"10.1023\/A:1007502828372"},{"key":"CIT0159","doi-asserted-by":"publisher","DOI":"10.1006\/mthe.2000.0142"},{"key":"CIT0161","doi-asserted-by":"publisher","DOI":"10.1038\/nrd744"},{"key":"CIT0163","doi-asserted-by":"publisher","DOI":"10.1054\/ijom.2002.0244"},{"key":"CIT0165","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.23.11307"},{"key":"CIT0166","doi-asserted-by":"publisher","DOI":"10.1016\/S0939-6411(98)00017-4"},{"key":"CIT0167","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-5173(01)00691-3"},{"key":"CIT0170","first-page":"11","volume":"17","author":"BOYNE PJ","year":"1997","journal-title":"Int. J Periodont Restor. Dent."},{"key":"CIT0171","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-3659(99)00129-7"},{"key":"CIT0172","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820200110"},{"key":"CIT0173","doi-asserted-by":"crossref","first-page":"877","DOI":"10.4049\/jimmunol.136.3.877","volume":"136","author":"ELLINGSWORTH LR","year":"1986","journal-title":"J Immunol"},{"key":"CIT0174","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4636(199621)33:1<35::AID-JBM6>3.0.CO;2-N"},{"key":"CIT0175","doi-asserted-by":"publisher","DOI":"10.1016\/0168-3659(89)90088-6"},{"key":"CIT0176","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4636(19980315)39:4<539::AID-JBM6>3.0.CO;2-K"},{"key":"CIT0177","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-3659(97)10055-4"},{"key":"CIT0178","first-page":"415","volume":"79","author":"MOURSI AM","year":"2000","journal-title":"Dent. Res"},{"key":"CIT0179","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569(2003)040<0225:DOTGFA>2.0.CO;2"},{"key":"CIT0183","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1997.68.12.1186"},{"key":"CIT0184","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1182\/blood.V64.2.458.458","volume":"64","author":"BOWEN-POPE DF","year":"1984","journal-title":"Blood"},{"key":"CIT0185","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.4.1513"},{"key":"CIT0186","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2002.tb03047.x"},{"key":"CIT0187","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200202000-00047"},{"key":"CIT0188","first-page":"187","volume":"9","author":"WARREN SM","year":"2003","journal-title":"Tics. Eng."},{"key":"CIT0190","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1998.tb09645.x"},{"key":"CIT0191","doi-asserted-by":"publisher","DOI":"10.1097\/00001665-200011010-00005"},{"key":"CIT0192","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200107000-00003"},{"key":"CIT0193","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200208000-00022"},{"key":"CIT0194","doi-asserted-by":"publisher","DOI":"10.1106\/RA7U-1V9C-RV7C-8QXL"},{"key":"CIT0196","doi-asserted-by":"publisher","DOI":"10.1038\/10473"},{"key":"CIT0199","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-199905000-00005"}],"container-title":["Expert Opinion on Biological Therapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/14712598.4.3.279","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T03:07:55Z","timestamp":1735700875000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1517\/14712598.4.3.279"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3]]},"references-count":151,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2005,3,3]]},"published-print":{"date-parts":[[2004,3]]}},"alternative-id":["10.1517\/14712598.4.3.279"],"URL":"https:\/\/doi.org\/10.1517\/14712598.4.3.279","relation":{},"ISSN":["1471-2598","1744-7682"],"issn-type":[{"value":"1471-2598","type":"print"},{"value":"1744-7682","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,3]]}}}