{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T03:37:09Z","timestamp":1772077029711,"version":"3.50.1"},"reference-count":89,"publisher":"Informa Healthcare","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Expert Opinion on Biological Therapy"],"published-print":{"date-parts":[[2007,10]]},"DOI":"10.1517\/14712598.7.10.1597","type":"journal-article","created":{"date-parts":[[2007,10,5]],"date-time":"2007-10-05T11:56:59Z","timestamp":1191585419000},"page":"1597-1611","source":"Crossref","is-referenced-by-count":20,"title":["Imatinib mesylate in the treatment of hematologic malignancies"],"prefix":"10.1517","volume":"7","author":[{"given":"Pier Paolo","family":"Piccaluga","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michela","family":"Rondoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefania","family":"Paolini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianantonio","family":"Rosti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Martinelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Baccarani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3197","published-online":{"date-parts":[[2007,10,5]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(02)80599-8"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200161120-00007"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1172\/JCI26833"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200363050-00005"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8588(05)70198-2"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1567"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1038\/344251a0"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1126\/science.2406902"},{"key":"CIT0011","doi-asserted-by":"crossref","first-page":"3780","DOI":"10.1182\/blood.V92.10.3780","volume":"92","author":"PEAR","year":"1998","journal-title":"Blood"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198810133191506"},{"key":"CIT0013","first-page":"1163","volume":"7","author":"RASKIND","year":"1993","journal-title":"Leukemia"},{"key":"CIT0014","doi-asserted-by":"crossref","first-page":"3118","DOI":"10.1182\/blood.V86.8.3118.3118","volume":"86","author":"BIERNAUX","year":"1995","journal-title":"Blood"},{"key":"CIT0015","doi-asserted-by":"crossref","first-page":"3362","DOI":"10.1182\/blood.V92.9.3362","volume":"92","author":"BOSE","year":"1998","journal-title":"Blood"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2403241"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2003.10.005"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-06-2147"},{"key":"CIT0019","first-page":"100","volume":"56","author":"BUCHDUNGER","year":"1996","journal-title":"Cancer Res."},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V97.8.2440"},{"key":"CIT0021","first-page":"139","volume":"295","author":"BUCHDUNGER","year":"2000","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.4161\/cc.4.7.1788"},{"key":"CIT0023","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1182\/blood.V96.3.925","volume":"96","author":"HEINRICH","year":"2000","journal-title":"Blood"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2403313"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa025217"},{"key":"CIT0026","first-page":"596","volume":"90","author":"LA","year":"2005","journal-title":"Haematologica"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-03-0787"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2403722"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-05-1627"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0601192103"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-4183"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminhematol.2007.02.002"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200104053441402"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V99.6.1928"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V99.10.3530"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa022457"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa062867"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2001-12-0181"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2402770"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-02-0360"},{"key":"CIT0041","first-page":"1269","volume":"89","author":"PICCALUGA","year":"2004","journal-title":"Haematologica"},{"key":"CIT0042","first-page":"4674","volume":"9","author":"PFEIFER","year":"2003","journal-title":"Clin. Cancer Res."},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-11-4386"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-08-2958"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-04-1389"},{"key":"CIT0046","volume":"104","author":"RIBERA","year":"2004","journal-title":"Blood"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2404065"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1016\/S1040-8428(00)00097-4"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-10-052746"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22631"},{"key":"CIT0051","volume":"104","author":"DELANNOY","year":"2004","journal-title":"Blood"},{"key":"CIT0052","doi-asserted-by":"crossref","first-page":"2602","DOI":"10.1182\/blood.V89.7.2602","volume":"89","author":"RADICH","year":"1997","journal-title":"Blood"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-05-1746"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1517\/14712598.6.10.1011"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22881"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1159\/000085559"},{"key":"CIT0057","author":"BACCARANI","year":"2007","journal-title":"Haematologica"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-004-0845-z"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2403229"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2005.02.014"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-10-050054"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12468882"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12469049"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199301283280408"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199305063281803"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1038\/ng0396-312"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.20.6.1692"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1172\/JCI116761"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)14115-3"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.21996"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-472X(03)00112-7"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa020150"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-05-024828"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(05)70213-8"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1038\/nm1446"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1038\/nm0107-15a"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1038\/nm0107-14"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-01-070144"},{"key":"CIT0080","doi-asserted-by":"publisher","DOI":"10.1038\/nm0107-13a"},{"key":"CIT0081","doi-asserted-by":"publisher","DOI":"10.1126\/science.289.5486.1938"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111525200"},{"key":"CIT0083","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-12-3659"},{"key":"CIT0084","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(03)00979-3"},{"key":"CIT0085","doi-asserted-by":"publisher","DOI":"10.1126\/science.1099480"},{"key":"CIT0086","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminhematol.2006.12.002"},{"key":"CIT0087","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-09-2896"},{"key":"CIT0088","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.05.531"},{"key":"CIT0089","doi-asserted-by":"publisher","DOI":"10.1080\/10428190310001625755"},{"key":"CIT0090","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2402889"},{"key":"CIT0091","volume":"106","author":"PFEIFER","year":"2005","journal-title":"Blood"},{"key":"CIT0092","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-04-1180"}],"container-title":["Expert Opinion on Biological Therapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/14712598.7.10.1597","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,27]],"date-time":"2020-04-27T01:49:39Z","timestamp":1587952179000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1517\/14712598.7.10.1597"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,10]]},"references-count":89,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2007,10,5]]},"published-print":{"date-parts":[[2007,10]]}},"alternative-id":["10.1517\/14712598.7.10.1597"],"URL":"https:\/\/doi.org\/10.1517\/14712598.7.10.1597","relation":{},"ISSN":["1471-2598","1744-7682"],"issn-type":[{"value":"1471-2598","type":"print"},{"value":"1744-7682","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,10]]}}}