{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T01:52:12Z","timestamp":1780105932047,"version":"3.54.0"},"reference-count":87,"publisher":"Informa Healthcare","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Expert Opinion on Biological Therapy"],"published-print":{"date-parts":[[2007,5]]},"DOI":"10.1517\/14712598.7.5.713","type":"journal-article","created":{"date-parts":[[2007,5,3]],"date-time":"2007-05-03T17:09:27Z","timestamp":1178212167000},"page":"713-726","source":"Crossref","is-referenced-by-count":40,"title":["Experimental treatments for human transmissible spongiform encephalopathies: is there a role for pentosan polysulfate?"],"prefix":"10.1517","volume":"7","author":[{"given":"N G","family":"Rainov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y","family":"Tsuboi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Krolak-Salmon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Vighetto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Doh-ura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3197","published-online":{"date-parts":[[2007,5,3]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.mi.48.100194.003255"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.23.13363"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1038\/379339a0"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2000.0764"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1093\/bmb\/66.1.109"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1016\/S1359-0278(96)00007-7"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1038\/nature01979"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1038\/380345a0"},{"key":"CIT0009","first-page":"883","volume":"12","author":"BROWN","year":"1997","journal-title":"Histol. Histopathol."},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0173(01)00042-X"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.1999.0731105.x"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/16.20.6057"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-3639.1998.tb00167.x"},{"key":"CIT0014","volume-title":"Nature Encyclopedia of Life Sciences.","author":"HEPPNER","year":"2007"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1093\/bmb\/66.1.267"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1002\/elps.1150190815"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-3639.1995.tb00576.x"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.55.8.1075"},{"key":"CIT0019","first-page":"123","volume":"81","author":"SMITH","year":"2003","journal-title":"Bull. World Health Organ."},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000231528.65069.3f"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199202133260704"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0173(96)00010-0"},{"key":"CIT0023","first-page":"120","volume":"42","author":"LIBERSKI","year":"2004","journal-title":"Folia Neuropathol."},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)91412-9"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1038\/39057"},{"key":"CIT0026","first-page":"143","volume":"16","author":"IRONSIDE","year":"2000","journal-title":"Arch. Virol. Suppl."},{"key":"CIT0027","first-page":"133","volume":"284","author":"IRONSIDE","year":"2004","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.324.7352.1479"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1093\/bmb\/66.1.241"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1016\/S0047-6374(00)00112-3"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1016\/S0966-842X(99)01656-X"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)05748-8"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1016\/S1471-4914(03)00144-8"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awl150"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00715-06"},{"key":"CIT0036","doi-asserted-by":"crossref","first-page":"7534","DOI":"10.1128\/JVI.68.11.7534-7536.1994","volume":"68","author":"MCKENZIE","year":"1994","journal-title":"J. Virol."},{"key":"CIT0037","doi-asserted-by":"crossref","first-page":"3511","DOI":"10.1128\/JVI.73.4.3511-3513.1999","volume":"73","author":"DEMAIMAY","year":"1999","journal-title":"J. Virol."},{"key":"CIT0038","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1099\/0022-1317-80-4-1079","volume":"80","author":"ADJOU","year":"1999","journal-title":"J. Gen. Virol."},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1992.tb09437.x"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.6.3484"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1126\/science.276.5315.1119"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)79191-1"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/20.15.3957"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.24.14793"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1126\/science.287.5457.1503"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1006\/neur.1995.0044"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1016\/0922-4106(94)90006-X"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000113764.35026.EF"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.10.4894-4897.2000"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.161274798"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200309150-00017"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1002\/ana.10336"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.77.15.8462-8469.2003"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1016\/j.surneu.2005.03.035"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000148596.15681.4D"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1159\/000076350"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-72-2-457"},{"key":"CIT0058","first-page":"163","volume":"22","author":"CAUGHEY","year":"1994","journal-title":"Biochem. Neurodegen. Disord."},{"key":"CIT0059","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1128\/JVI.68.4.2135-2141.1994","volume":"68","author":"CAUGHEY","year":"1994","journal-title":"J. Virol."},{"key":"CIT0060","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1128\/JVI.67.2.643-650.1993","volume":"67","author":"CAUGHEY","year":"1993","journal-title":"J. Virol."},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1042\/bj3350369"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-67-3-463"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-65-8-1325"},{"key":"CIT0064","first-page":"37","volume":"135","author":"KIMBERLIN","year":"1988","journal-title":"Ciba Found. Symp."},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-73-3-661"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)05395-1"},{"key":"CIT0067","first-page":"4999","volume":"78","author":"DOH-URA","year":"2004","journal-title":"J"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1016\/0049-3848(86)90169-6"},{"key":"CIT0069","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1055\/s-0038-1648472","volume":"67","author":"DAWES","year":"1992","journal-title":"Thromb. Haemost."},{"key":"CIT0070","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1055\/s-0038-1661326","volume":"53","author":"MCGREGOR","year":"1985","journal-title":"Thromb. Haemost."},{"key":"CIT0071","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1055\/s-0038-1661453","volume":"55","author":"SIE","year":"1986","journal-title":"Thromb. Haemost."},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(90)80116-5"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830450312"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1006\/exnr.1996.0125"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1038\/nm850"},{"key":"CIT0076","first-page":"219","volume":"7","author":"CORNFORD","year":"1985","journal-title":"Mol. Physiol."},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000097715.11966.8E"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199805000-00082"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2004.04.001"},{"key":"CIT0080","first-page":"133","volume":"32","author":"PAKULSKI","year":"1998","journal-title":"Neurol. Neurochir. Pol."},{"key":"CIT0081","doi-asserted-by":"publisher","DOI":"10.1016\/0165-3806(85)90255-X"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.1088\/0967-3334\/25\/5\/R01"},{"key":"CIT0083","first-page":"285","volume":"70","author":"FENSTERMACHER","year":"1997","journal-title":"Acta Neurochir. Suppl."},{"key":"CIT0084","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2003.11.006"},{"key":"CIT0085","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2004.07.015"},{"key":"CIT0086","author":"PARRY","year":"2007","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"CIT0087","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-006-0772-y"}],"container-title":["Expert Opinion on Biological Therapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/14712598.7.5.713","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,21]],"date-time":"2020-04-21T17:56:46Z","timestamp":1587491806000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1517\/14712598.7.5.713"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":87,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2007,5,3]]},"published-print":{"date-parts":[[2007,5]]}},"alternative-id":["10.1517\/14712598.7.5.713"],"URL":"https:\/\/doi.org\/10.1517\/14712598.7.5.713","relation":{},"ISSN":["1471-2598","1744-7682"],"issn-type":[{"value":"1471-2598","type":"print"},{"value":"1744-7682","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,5]]}}}