{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T00:48:49Z","timestamp":1793753329720,"version":"4.6.1"},"reference-count":78,"publisher":"Informa UK Limited","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Expert Opinion on Therapeutic Targets"],"published-print":{"date-parts":[[2008,6]]},"DOI":"10.1517\/14728222.12.6.717","type":"journal-article","created":{"date-parts":[[2008,5,15]],"date-time":"2008-05-15T05:16:37Z","timestamp":1210828597000},"page":"717-727","source":"Crossref","is-referenced-by-count":304,"title":["The paraventricular nucleus of the hypothalamus \u2013 a potential target for integrative treatment of autonomic dysfunction"],"prefix":"10.1517","volume":"12","author":[{"given":"Alastair V","family":"Ferguson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin J","family":"Latchford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willis K","family":"Samson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2008,5,15]]},"reference":[{"key":"CIT0001","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1159\/000123111","volume":"31","author":"Swanson","year":"1980","journal-title":"Neuroendocrinology"},{"key":"CIT0002","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1677\/joe.0.1770017","volume":"177","author":"Buijs","year":"2003","journal-title":"J Endocrinol"},{"key":"CIT0003","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1159\/000109434","volume":"4","author":"Coote","year":"1995","journal-title":"Biol Signals"},{"key":"CIT0004","first-page":"68","volume":"20","author":"Kalra","year":"1999","journal-title":"Endocr Rev"},{"key":"CIT0005","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1017\/S0029665100000434","volume":"59","author":"Williams","year":"2000","journal-title":"Proc Nutr Soc"},{"key":"CIT0006","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1113\/jphysiol.1991.sp018469","volume":"434","author":"Tasker","year":"1991","journal-title":"J Physiol (Lond)"},{"key":"CIT0007","doi-asserted-by":"crossref","first-page":"2829","DOI":"10.1523\/JNEUROSCI.13-07-02829.1993","volume":"13","author":"van den Pol","year":"1993","journal-title":"J Neurosci"},{"key":"CIT0008","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1002\/cne.903020423","volume":"302","author":"Decavel","year":"1990","journal-title":"J Comp Neurol"},{"key":"CIT0009","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/S0306-4522(00)00411-5","volume":"101","author":"Csaki","year":"2000","journal-title":"Neuroscience"},{"key":"CIT0011","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1038\/nrn1845","volume":"7","author":"Ludwig","year":"2006","journal-title":"Nat Rev Neurosci"},{"key":"CIT0012","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0166-2236(03)00072-9","volume":"26","author":"Ludwig","year":"2003","journal-title":"Trends Neurosci"},{"key":"CIT0013","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1523\/JNEUROSCI.2676-06.2007","volume":"27","author":"Oliet","year":"2007","journal-title":"J Neurosci"},{"key":"CIT0014","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1159\/000124046","volume":"40","author":"Lind","year":"1985","journal-title":"Neuroendocrinology"},{"key":"CIT0015","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1159\/000125241","volume":"50","author":"Shoji","year":"1989","journal-title":"Neuroendocrinology"},{"key":"CIT0016","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1254\/jjp.66.241","volume":"66","author":"Tsushima","year":"1994","journal-title":"Jpn J Pharmacol"},{"key":"CIT0017","doi-asserted-by":"crossref","first-page":"H2039","DOI":"10.1152\/ajpheart.00854.2001","volume":"282","author":"Zhu","year":"2002","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"CIT0018","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0006-8993(92)90395-P","volume":"599","author":"Bains","year":"1992","journal-title":"Brain Res"},{"key":"CIT0019","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1159\/000124015","volume":"39","author":"Ferguson","year":"1984","journal-title":"Neuroendocrinology"},{"key":"CIT0020","first-page":"R1088","volume":"247","author":"Ferguson","year":"1984","journal-title":"Am J Physiol"},{"key":"CIT0021","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0361-9230(93)90036-B","volume":"30","author":"Li","year":"1993","journal-title":"Brain Res Bull"},{"key":"CIT0022","first-page":"R302","volume":"265","author":"Li","year":"1993","journal-title":"Am J Physiol"},{"key":"CIT0023","doi-asserted-by":"crossref","first-page":"R894","DOI":"10.1152\/ajpregu.00603.2003","volume":"286","author":"Latchford","year":"2004","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"CIT0024","doi-asserted-by":"crossref","first-page":"R52","DOI":"10.1152\/ajpregu.00549.2004","volume":"289","author":"Latchford","year":"2005","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"CIT0025","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S0092-8674(00)80949-6","volume":"92","author":"Sakurai","year":"1998","journal-title":"Cell"},{"key":"CIT0026","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1073\/pnas.95.1.322","volume":"95","author":"de Lecea","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"CIT0027","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/S0092-8674(00)81973-X","volume":"98","author":"Chemelli","year":"1999","journal-title":"Cell"},{"key":"CIT0028","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S1043-2760(00)00273-3","volume":"11","author":"Samson","year":"2000","journal-title":"Trends Endocrinol Metab"},{"key":"CIT0029","doi-asserted-by":"crossref","first-page":"R7","DOI":"10.1677\/joe.0.160R007","volume":"160","author":"Edwards","year":"1999","journal-title":"J Endocrinol"},{"key":"CIT0030","doi-asserted-by":"crossref","first-page":"R1114","DOI":"10.1152\/ajpregu.2001.281.4.R1114","volume":"281","author":"Shirasaka","year":"2001","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"CIT0031","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1113\/jphysiol.2002.030049","volume":"545","author":"Follwell","year":"2002","journal-title":"J Physiol"},{"key":"CIT0032","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0167-0115(01)00353-6","volume":"104","author":"Samson","year":"2002","journal-title":"Regul Pept"},{"key":"CIT0033","doi-asserted-by":"crossref","first-page":"6643","DOI":"10.1523\/JNEUROSCI.5126-05.2006","volume":"26","author":"Malcher-Lopes","year":"2006","journal-title":"J Neurosci"},{"key":"CIT0034","first-page":"R1468","volume":"274","author":"Powis","year":"1997","journal-title":"Am J Physiol"},{"key":"CIT0035","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1046\/j.1365-2826.2003.00870.x","volume":"15","author":"Ferri","year":"2003","journal-title":"J Neuroendocrinol"},{"key":"CIT0036","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.regpep.2005.01.004","volume":"129","author":"Ferri","year":"2005","journal-title":"Regul Pept"},{"key":"CIT0037","doi-asserted-by":"crossref","first-page":"26746","DOI":"10.1074\/jbc.270.45.26746","volume":"270","author":"Scherer","year":"1995","journal-title":"J Biol Chem"},{"key":"CIT0038","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1210\/er.2005-0005","volume":"26","author":"Kadowaki","year":"2005","journal-title":"Endocr Rev"},{"key":"CIT0039","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1038\/90992","volume":"7","author":"Berg","year":"2001","journal-title":"Nat Med"},{"key":"CIT0040","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1172\/JCI14120","volume":"108","author":"Combs","year":"2001","journal-title":"J Clin Invest"},{"key":"CIT0041","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1038\/90984","volume":"7","author":"Yamauchi","year":"2001","journal-title":"Nat Med"},{"key":"CIT0042","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1038\/nm1029","volume":"10","author":"Qi","year":"2004","journal-title":"Nat Med"},{"key":"CIT0043","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1111\/j.1460-9568.2006.05293.x","volume":"25","author":"Yuill","year":"2007","journal-title":"Eur J Neurosci"},{"key":"CIT0044","doi-asserted-by":"crossref","first-page":"10619","DOI":"10.1523\/JNEUROSCI.18-24-10619.1998","volume":"18","author":"Daftary","year":"1998","journal-title":"J Neurosci"},{"key":"CIT0045","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1152\/jn.00171.2004","volume":"92","author":"Li","year":"2004","journal-title":"J Neurophysiol"},{"key":"CIT0046","first-page":"R306","volume":"266","author":"Horn","year":"1994","journal-title":"Am J Physiol"},{"key":"CIT0047","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1113\/jphysiol.1997.sp021965","volume":"499","author":"Bains","year":"1997","journal-title":"J Physiol (Lond)"},{"key":"CIT0048","doi-asserted-by":"crossref","first-page":"R1293","DOI":"10.1152\/ajpregu.00191.2002","volume":"283","author":"Follwell","year":"2002","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"CIT0049","doi-asserted-by":"crossref","first-page":"5041","DOI":"10.1523\/JNEUROSCI.23-12-05041.2003","volume":"23","author":"Li","year":"2003","journal-title":"J Neurosci"},{"key":"CIT0050","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1080\/10253890701350735","volume":"10","author":"Saavedra","year":"2007","journal-title":"Stress"},{"key":"CIT0051","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.brainres.2007.01.037","volume":"1142","author":"Armando","year":"2007","journal-title":"Brain Res"},{"key":"CIT0052","doi-asserted-by":"crossref","first-page":"R259","DOI":"10.1152\/ajpregu.00317.2002","volume":"284","author":"Felder","year":"2003","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"CIT0053","first-page":"R923","volume":"265","author":"Patel","year":"1993","journal-title":"Am J Physiol"},{"key":"CIT0054","first-page":"S16","volume":"32","author":"Francis","year":"1998","journal-title":"J Cardiovasc Pharmacol"},{"key":"CIT0055","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1161\/01.CIR.92.3.286","volume":"92","author":"Jougasaki","year":"1995","journal-title":"Circulation"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(99)00358-6"},{"key":"CIT0057","first-page":"R213","volume":"276","author":"Nagaya","year":"1999","journal-title":"Am J Physiol"},{"key":"CIT0058","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1093\/eurheartj\/11.suppl_B.79","volume":"11","author":"Riegger","year":"1990","journal-title":"Eur Heart J"},{"key":"CIT0059","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0196-9781(86)90057-4","volume":"7","author":"Tang","year":"1986","journal-title":"Peptides"},{"key":"CIT0060","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1046\/j.1365-201X.2003.01043.x","volume":"177","author":"Li","year":"2003","journal-title":"Acta Physiol Scand"},{"key":"CIT0061","doi-asserted-by":"crossref","first-page":"R728","DOI":"10.1152\/ajpcell.1998.275.4.C1104","volume":"275","author":"Zhang","year":"1998","journal-title":"Am J Physiol"},{"key":"CIT0062","first-page":"R864","volume":"273","author":"Zhang","year":"1997","journal-title":"Am J Physiol Renal Fluid Electrolyte Physiol"},{"key":"CIT0063","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1111\/j.1440-1681.1996.tb01765.x","volume":"23","author":"Patel","year":"1996","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"CIT0064","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0167-0115(94)90191-0","volume":"50","author":"Bains","year":"1994","journal-title":"Regul Pept"},{"key":"CIT0065","doi-asserted-by":"crossref","first-page":"H2140","DOI":"10.1152\/ajpheart.1998.275.6.H2140","volume":"275","author":"Vahid-Ansari","year":"1998","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"CIT0066","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s10286-005-0297-0","volume":"15","author":"Coote","year":"2005","journal-title":"Clin Auton Res"},{"key":"CIT0067","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0006-8993(97)01449-2","volume":"786","author":"Zhang","year":"1998","journal-title":"Brain Res"},{"key":"CIT0068","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1023\/A:1009850224802","volume":"5","author":"Patel","year":"2000","journal-title":"Heart Fail Rev"},{"key":"CIT0069","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0006-8993(94)01222-4","volume":"669","author":"Earle","year":"1995","journal-title":"Brain Res"},{"key":"CIT0070","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/0014-4886(90)90154-K","volume":"107","author":"Meyer","year":"1990","journal-title":"Exp Neurol"},{"key":"CIT0071","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1097\/00004872-198808000-00002","volume":"6","author":"Phillips","year":"1988","journal-title":"J Hypertens"},{"key":"CIT0072","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1097\/00004872-198801000-00012","volume":"6","author":"Gutkind","year":"1988","journal-title":"J Hypertens"},{"key":"CIT0073","doi-asserted-by":"crossref","first-page":"2664","DOI":"10.1152\/jn.00540.2002","volume":"88","author":"Li","year":"2002","journal-title":"J Neurophysiol"},{"key":"CIT0074","first-page":"R864","volume":"273","author":"Zhang","year":"1997","journal-title":"Am J Physiol"},{"key":"CIT0075","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1097\/00004872-199816050-00010","volume":"16","author":"Horn","year":"1998","journal-title":"J Hypertens"},{"key":"CIT0076","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0361-9230(94)00164-V","volume":"36","author":"Kunkler","year":"1995","journal-title":"Brain Res Bull"},{"key":"CIT0077","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1124\/jpet.106.109538","volume":"320","author":"Li","year":"2007","journal-title":"J Pharmacol Exp Ther"},{"key":"CIT0078","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1113\/jphysiol.2007.144519","volume":"585","author":"Hoyda","year":"2007","journal-title":"J Physiol"},{"key":"CIT0079","doi-asserted-by":"crossref","first-page":"4801","DOI":"10.1210\/endo.141.12.7949","volume":"141","author":"Ziegler","year":"2000","journal-title":"Endocrinology"}],"container-title":["Expert Opinion on Therapeutic Targets"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/14728222.12.6.717","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,11]],"date-time":"2019-05-11T07:32:36Z","timestamp":1557559956000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1517\/14728222.12.6.717"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5,15]]},"references-count":78,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2008,5,15]]},"published-print":{"date-parts":[[2008,6]]}},"alternative-id":["10.1517\/14728222.12.6.717"],"URL":"https:\/\/doi.org\/10.1517\/14728222.12.6.717","relation":{},"ISSN":["1472-8222","1744-7631"],"issn-type":[{"value":"1472-8222","type":"print"},{"value":"1744-7631","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,5,15]]}}}