{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T10:34:56Z","timestamp":1768732496720,"version":"3.49.0"},"reference-count":120,"publisher":"Informa UK Limited","issue":"6","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Therapeutic Targets"],"published-print":{"date-parts":[[2016,6,2]]},"DOI":"10.1517\/14728222.2015.1134489","type":"journal-article","created":{"date-parts":[[2015,12,19]],"date-time":"2015-12-19T09:28:58Z","timestamp":1450517338000},"page":"721-736","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":11,"title":["Targeting mitochondrial function to protect against vision loss"],"prefix":"10.1517","volume":"20","author":[{"given":"Jamuna","family":"Chhetri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuri","family":"Gueven","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2016,1,13]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.099234"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2013.10.040"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2008.09.001"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0b013e328349419d"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2009.10.002"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2010.11.002"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2415-14-77"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2012.03.007"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.4103\/0974-9233.51998"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2008.154187"},{"issue":"1","key":"CIT0011","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1093\/brain\/awn269","volume":"132","author":"Fortuna F","year":"2009","journal-title":"Brain"},{"issue":"2","key":"CIT0012","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1177\/112067210201200202","volume":"12","author":"Al-Till M","year":"2002","journal-title":"Eur J Ophthalmol"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1016\/j.mito.2013.05.013"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.112.192138"},{"key":"CIT0015","first-page":"908306","volume":"2011","author":"Armstrong RA","year":"2011","journal-title":"Parkinsons Dis"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0085718"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.2174\/156720510790274491"},{"issue":"2","key":"CIT0018","doi-asserted-by":"crossref","first-page":"237","DOI":"10.3233\/JAD-132105","volume":"40","author":"Krantic S","year":"2014","journal-title":"J Alzheimers Dis"},{"issue":"4","key":"CIT0019","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.3233\/JAD-140507","volume":"42","author":"Nolan JM","year":"2014","journal-title":"J Alzheimers Dis"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-008-0985-5"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejhg.5201108"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.2007.00882.x"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1097\/WNO.0b013e3181b1b3f8"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.4103\/0028-3886.68674"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1007\/s12311-012-0412-4"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2415-14-104"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1100\/tsw.2008.62"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1186\/s40942-015-0001-z"},{"key":"CIT0029","first-page":"1411","volume":"18","author":"Yang Y","year":"2012","journal-title":"Mol Vis"},{"issue":"5","key":"CIT0030","doi-asserted-by":"crossref","first-page":"e0125919","DOI":"10.1371\/journal.pone.0125919","volume":"10","author":"Chen X","year":"2015","journal-title":"Plos One"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.11-8538"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2013.04.015"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2012.09.008"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4614-0653-2_2"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.14-14633"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.13-12172"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2012.03.010"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/428010"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2011.08.017"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1016\/j.tig.2013.05.005"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1159\/000316480"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2003.10.003"},{"issue":"101","key":"CIT0043","first-page":"2","volume":"1","author":"Gueven N","year":"2014","journal-title":"Biol Med"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.02-0333"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awq155"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0050230"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1086\/519394"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2009.165571"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbabio.2011.10.014"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1093\/bmb\/ldt017"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2009.072058"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0906784106"},{"issue":"3","key":"CIT0053","first-page":"517","volume":"140","author":"Newman NJ","year":"2005","journal-title":"Am J Ophthalmol"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2011.06.106"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-009-0546-8"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2003.tb00469.x"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-007-2888-2_17"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0045182"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1097\/WNO.0b013e318273c102"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)92366-0"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.138"},{"issue":"8","key":"CIT0062","volume":"14","author":"Reddy PH","year":"2009","journal-title":"CNS Spectr"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2010.06.020"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2013.00169"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2012.168"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2009.09.009"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000437308.22603.43"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-009-0060-3"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.2174\/138920111794480507"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2006.02.016"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2007.132308"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1038\/414813a"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2003.08.018"},{"key":"CIT0074","doi-asserted-by":"crossref","first-page":"21976","DOI":"10.1155\/2007\/21976","volume":"2007","author":"Kowluru RA","year":"2007","journal-title":"Exp Diabetes Res"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2015.08.001"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1038\/35008121"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6123(08)01101-1"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0042387"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6123(08)01124-2"},{"key":"CIT0080","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00481.2007"},{"key":"CIT0081","doi-asserted-by":"publisher","DOI":"10.1097\/00055735-200212000-00004"},{"key":"CIT0082","first-page":"1074","volume":"17","author":"Bosley TM","year":"2011","journal-title":"Mol Vis"},{"key":"CIT0083","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.07-1361"},{"key":"CIT0084","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2010.03.008"},{"key":"CIT0085","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2014.08.012"},{"key":"CIT0086","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.082230"},{"issue":"5","key":"CIT0087","first-page":"2013","volume":"105","author":"Osborne NN","year":"2008","journal-title":"J Neuro Chem"},{"key":"CIT0088","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.07-0170"},{"key":"CIT0089","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.12-9596"},{"key":"CIT0090","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2010.09.002"},{"key":"CIT0091","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2005.05.012"},{"key":"CIT0092","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-6163"},{"key":"CIT0093","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0190-15.2015"},{"key":"CIT0094","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2007.07.013"},{"key":"CIT0095","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.200700075"},{"key":"CIT0096","doi-asserted-by":"publisher","DOI":"10.1016\/j.ohc.2004.05.005"},{"key":"CIT0097","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-004-1053-1"},{"key":"CIT0098","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2007.01.011"},{"key":"CIT0099","doi-asserted-by":"publisher","DOI":"10.1097\/01.icu.0000434557.30065.a7"},{"key":"CIT0100","doi-asserted-by":"publisher","DOI":"10.1097\/FJC.0b013e31829f9e40"},{"issue":"3","key":"CIT0101","first-page":"336","volume":"31","author":"Hroudova J","year":"2010","journal-title":"Neuro Endocrinol Lett"},{"key":"CIT0102","doi-asserted-by":"publisher","DOI":"10.1358\/dot.2007.43.11.1157621"},{"key":"CIT0103","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2012.05.006"},{"key":"CIT0104","doi-asserted-by":"publisher","DOI":"10.1097\/WNO.0b013e3182901969"},{"key":"CIT0105","doi-asserted-by":"publisher","DOI":"10.1016\/S0028-3908(98)00215-9"},{"issue":"1","key":"CIT0106","first-page":"25","volume":"31","author":"Fosslien E","year":"2001","journal-title":"Ann Clin Lab Sci"},{"key":"CIT0107","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(98)01033-3"},{"key":"CIT0108","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-2952(98)00330-X"},{"key":"CIT0109","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.533588"},{"key":"CIT0110","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2012.11.002"},{"key":"CIT0111","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2013.07.038"},{"key":"CIT0112","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2006.102541"},{"key":"CIT0113","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-1097.2012.01144.x"},{"key":"CIT0114","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2010.11.016"},{"key":"CIT0115","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2013.12.011"},{"key":"CIT0116","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awr170"},{"key":"CIT0117","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/aws280"},{"key":"CIT0118","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e31824caf90"},{"key":"CIT0119","first-page":"020248","volume":"23","author":"Alam NM","year":"2015","journal-title":"Dis Model Mech"},{"issue":"4","key":"CIT0120","first-page":"130","volume":"2","author":"Gueven N","year":"2013","journal-title":"Intractable Rare Dis Res"}],"container-title":["Expert Opinion on Therapeutic Targets"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/14728222.2015.1134489","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,31]],"date-time":"2025-05-31T21:41:06Z","timestamp":1748727666000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1517\/14728222.2015.1134489"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1,13]]},"references-count":120,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2015,12,19]]},"published-print":{"date-parts":[[2016,6,2]]}},"alternative-id":["10.1517\/14728222.2015.1134489"],"URL":"https:\/\/doi.org\/10.1517\/14728222.2015.1134489","relation":{},"ISSN":["1472-8222","1744-7631"],"issn-type":[{"value":"1472-8222","type":"print"},{"value":"1744-7631","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1,13]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iett20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iett20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"}]}}