{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T08:56:55Z","timestamp":1791622615055,"version":"4.3.4"},"reference-count":85,"publisher":"Informa UK Limited","issue":"5","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Drug Safety"],"published-print":{"date-parts":[[2016,5,3]]},"DOI":"10.1517\/14740338.2016.1161021","type":"journal-article","created":{"date-parts":[[2016,3,2]],"date-time":"2016-03-02T17:20:55Z","timestamp":1456939255000},"page":"679-688","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":55,"title":["Cardiovascular safety of antipsychotics: a clinical overview"],"prefix":"10.1517","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9372-7484","authenticated-orcid":false,"given":"Christoffer","family":"Polcwiartek","sequence":"first","affiliation":[{"name":",","place":["Denmark"]},{"name":",","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristian","family":"Kragholm","sequence":"additional","affiliation":[{"name":",","place":["Denmark"]},{"name":",","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ole","family":"Schjerning","sequence":"additional","affiliation":[{"name":",","place":["Denmark"]},{"name":",","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claus","family":"Graff","sequence":"additional","affiliation":[{"name":",","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jimmi","family":"Nielsen","sequence":"additional","affiliation":[{"name":",","place":["Denmark"]},{"name":",","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2016,4]]},"reference":[{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2010.01610.x"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0806994"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.09m05318yel"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.161.8.1334"},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(15)00115-7"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2011.576665"},{"key":"e_1_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pra.0000450319.21859.6d"},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.2165\/11587800-000000000-00000"},{"key":"e_1_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0081208"},{"key":"e_1_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40264-013-0032-z"},{"key":"e_1_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40264-015-0353-1"},{"key":"e_1_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2014.139"},{"key":"e_1_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/cpt.250"},{"key":"e_1_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2006.00408.x"},{"key":"e_1_3_3_19_1","unstructured":"FDA. Psychopharmacological drugs advisory committee: briefing document for Zeldox\u00ae capsules (ziprasidone HCl). 2000. [cited 2016 Feb 17]. Available from: http:\/\/www.fda.gov\/ohrms\/dockets\/ac\/00\/backgrd\/3619b1a.pdf"},{"key":"e_1_3_3_20_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa051688"},{"key":"e_1_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60733-3"},{"key":"e_1_3_3_22_1","doi-asserted-by":"publisher","DOI":"10.1586\/14737175.7.7.829"},{"key":"e_1_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2.6.543"},{"key":"e_1_3_3_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/jhm.691"},{"key":"e_1_3_3_25_1","unstructured":"FDA. Atypical antipsychotic drugs information. 2015. [cited 2016 Feb 17]. Available from: http:\/\/www.fda.gov\/Drugs\/DrugSafety\/PostmarketDrugSafetyInformationforPatientsandProviders\/ucm094303.htm"},{"key":"e_1_3_3_26_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2011.560114"},{"key":"e_1_3_3_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40263-014-0196-9"},{"key":"e_1_3_3_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.jcp.0000104913.75206.62"},{"key":"e_1_3_3_29_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2013.773971"},{"key":"e_1_3_3_30_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2012.726984"},{"key":"e_1_3_3_31_1","unstructured":"FDA. Psychopharmacological drugs advisory committee: briefing document for NDA 20-644 (sertindole). 2009. [cited 2016 Feb 17]. Available from: http:\/\/www.fda.gov\/downloads\/AdvisoryCommittees\/CommitteesMeetingMaterials\/Drugs\/PsychopharmacologicDrugsAdvisoryCommittee\/UCM161901.pdf"},{"key":"e_1_3_3_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-015-4024-9"},{"key":"e_1_3_3_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2010.78"},{"key":"e_1_3_3_34_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740330902835493"},{"key":"e_1_3_3_35_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2014.854770"},{"key":"e_1_3_3_36_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2014.908183"},{"key":"e_1_3_3_37_1","doi-asserted-by":"publisher","DOI":"10.1177\/0004867412444625"},{"key":"e_1_3_3_38_1","unstructured":"ICH. The clinical evaluation of QT\/QTc interval prolongation and proarrhythmic potential for non-antiarrhythmic drugs. 2005. [cited 2016 Feb 17]. Available from: http:\/\/www.ich.org\/fileadmin\/Public_Web_Site\/ICH_Products\/Guidelines\/Efficacy\/E14\/E14_Guideline.pdf"},{"key":"e_1_3_3_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2011.224"},{"key":"e_1_3_3_40_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu100"},{"key":"e_1_3_3_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2009.05.006"},{"key":"e_1_3_3_42_1","doi-asserted-by":"publisher","DOI":"10.4330\/wjc.v7.i6.315"},{"key":"e_1_3_3_43_1","doi-asserted-by":"publisher","DOI":"10.1177\/2045125314560738"},{"key":"e_1_3_3_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2014.12.005"},{"key":"e_1_3_3_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2009.01534.x"},{"key":"e_1_3_3_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2010.51"},{"key":"e_1_3_3_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2009.04.011"},{"key":"e_1_3_3_48_1","doi-asserted-by":"publisher","DOI":"10.1177\/0091270009344853"},{"key":"e_1_3_3_49_1","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-200932070-00006"},{"key":"e_1_3_3_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2008.07.024"},{"key":"e_1_3_3_51_1","unstructured":"DSKP. [Clinically relevant psychopharmacological interactions]. 2010. [cited 2016 Feb 17]. Available from: http:\/\/www.psykofarmakologi.dk\/actioncards\/interaktioner.html"},{"key":"e_1_3_3_52_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-200443010-00003"},{"key":"e_1_3_3_53_1","doi-asserted-by":"publisher","DOI":"10.1177\/070674371506000503"},{"key":"e_1_3_3_54_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2012.683523"},{"key":"e_1_3_3_55_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.7.2.181"},{"key":"e_1_3_3_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2013.07.030"},{"key":"e_1_3_3_57_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2008.153346"},{"key":"e_1_3_3_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.2006.01286.x"},{"key":"e_1_3_3_59_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.2005.02362.x"},{"key":"e_1_3_3_60_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2001.00061.x"},{"key":"e_1_3_3_61_1","article-title":"Clozapine-induced reversible Brugada Syndrome","volume":"1","author":"Chong JH","year":"2015","unstructured":"Chong JH, Eversheim F. Clozapine-induced reversible Brugada Syndrome. GSTF J Adv Med Res (JAMR). 2015;1:18\u201320.","journal-title":"GSTF J Adv Med Res (JAMR)"},{"key":"e_1_3_3_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2012.04.003"},{"key":"e_1_3_3_63_1","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1H240"},{"key":"e_1_3_3_64_1","doi-asserted-by":"publisher","DOI":"10.1097\/00132580-200205000-00009"},{"key":"e_1_3_3_65_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.12r08064"},{"key":"e_1_3_3_66_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-015-4161-1"},{"key":"e_1_3_3_67_1","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-200023030-00004"},{"key":"e_1_3_3_68_1","doi-asserted-by":"publisher","DOI":"10.2165\/11591710-000000000-00000"},{"key":"e_1_3_3_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2013.04.002"},{"key":"e_1_3_3_70_1","doi-asserted-by":"publisher","DOI":"10.2165\/00044011-200323050-00001"},{"key":"e_1_3_3_71_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.7.5.525"},{"key":"e_1_3_3_72_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v65n0514"},{"key":"e_1_3_3_73_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.58.12.1172"},{"key":"e_1_3_3_74_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/273060"},{"key":"e_1_3_3_75_1","doi-asserted-by":"publisher","DOI":"10.2147\/NDT.S40554"},{"key":"e_1_3_3_76_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.2011.04043.x"},{"key":"e_1_3_3_77_1","doi-asserted-by":"publisher","DOI":"10.1111\/acps.12345"},{"key":"e_1_3_3_78_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu263"},{"key":"e_1_3_3_79_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.008779"},{"key":"e_1_3_3_80_1","doi-asserted-by":"publisher","DOI":"10.1017\/neu.2014.41"},{"key":"e_1_3_3_81_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.4.4.731"},{"key":"e_1_3_3_82_1","doi-asserted-by":"publisher","DOI":"10.1111\/acps.12416"},{"key":"e_1_3_3_83_1","doi-asserted-by":"crossref","unstructured":"Vang T Rosenzweig M Bruhn CH et al. Eosinophilic myocarditis during treatment with olanzapine \u2013 report of two possible cases. BMC Psychiatry. 2016;16:70.","DOI":"10.1186\/s12888-016-0776-y"},{"key":"e_1_3_3_84_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.108.049395"},{"key":"e_1_3_3_85_1","doi-asserted-by":"crossref","unstructured":"Nielsen J Young C Ifteni P et al. Worldwide differences in regulations of clozapine use. CNS Drugs. 2016;30:149\u2013161.","DOI":"10.1007\/s40263-016-0311-1"},{"key":"e_1_3_3_86_1","doi-asserted-by":"publisher","DOI":"10.3109\/00048674.2011.572852"},{"key":"e_1_3_3_87_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199807233390404"},{"key":"e_1_3_3_88_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2015.974549"},{"key":"e_1_3_3_89_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2014.935761"}],"container-title":["Expert Opinion on Drug Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/14740338.2016.1161021","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T12:44:33Z","timestamp":1770381873000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1517\/14740338.2016.1161021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4]]},"references-count":85,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,5,3]]}},"alternative-id":["10.1517\/14740338.2016.1161021"],"URL":"https:\/\/doi.org\/10.1517\/14740338.2016.1161021","relation":{},"ISSN":["1474-0338","1744-764X"],"issn-type":[{"value":"1474-0338","type":"print"},{"value":"1744-764X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieds20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieds20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2016-01-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-02-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-04-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}