{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T23:35:56Z","timestamp":1791070556891,"version":"4.1.0"},"reference-count":105,"publisher":"Informa UK Limited","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Expert Opinion on Drug Metabolism &amp; Toxicology"],"published-print":{"date-parts":[[2010,5]]},"DOI":"10.1517\/17425251003610640","type":"journal-article","created":{"date-parts":[[2010,4,19]],"date-time":"2010-04-19T12:00:10Z","timestamp":1271678410000},"page":"603-619","source":"Crossref","is-referenced-by-count":71,"title":["P-glycoprotein related drug interactions: clinical importance and a consideration of disease states"],"prefix":"10.1517","volume":"6","author":[{"given":"Caroline A","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack A","family":"Cook","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric L","family":"Reyner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis A","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2010,4,19]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2736(76)90160-7"},{"issue":"6","key":"CIT0002","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1056\/NEJMra020526","volume":"348","author":"Evans WE","year":"2003","journal-title":"N Engl J Med"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-409X(97)00043-4"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2007.08.043"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0701606"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1016\/S0928-0987(00)00177-9"},{"key":"CIT0007","author":"Paule B","year":"2009","journal-title":"Med Oncol"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00341-07"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2008.195"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-06-0155"},{"issue":"9","key":"CIT0011","doi-asserted-by":"crossref","first-page":"5769","DOI":"10.1074\/jbc.M707028200","volume":"283","author":"Lee JY","year":"2008","journal-title":"J Biol Chem"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1126\/science.1168750"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-005-6627-z"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1002\/jps.21114"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1021\/bi011211z"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1021\/cr9000226"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1021\/bi900373x"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2008.07.005"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1067\/mcp.2000.109156"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1080\/00498250802017715"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1002\/ardp.200600094"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1053\/cp.1999.v66.a101462"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-200746090-00005"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1172\/JCI6663"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.5414\/CPP38161"},{"issue":"11","key":"CIT0027","first-page":"3379","volume":"5","author":"Meerum Terwogt JM","year":"1999","journal-title":"Clin Cancer Res"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-007-0447-5"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.2009.03396.x"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2009.04.003"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1016\/S0163-7258(98)00016-3"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-6143.2001.10415.x"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.102.041921"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1016\/j.clpt.2004.02.008"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1016\/j.clpt.2005.01.022"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118699"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2003.08.027"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1172\/JCI1269"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.103.049452"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.108.059360"},{"issue":"1","key":"CIT0041","doi-asserted-by":"crossref","first-page":"108","DOI":"10.2967\/jnumed.108.056226","volume":"50","author":"Liow JS","year":"2009","journal-title":"J Nucl Med"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0701979"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.105.097931"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.108.058453"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2005.11.002"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.8-5-411"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1007\/s00280-001-0411-5"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1097\/01.cad.0000231480.07654.b5"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-4525"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-06-1357"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1124\/pr.107.07109"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19960801)78:3<527::AID-CNCR21>3.0.CO;2-#"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1172\/JCI0215451"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-0929"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2005.11.009"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.21227"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-3322"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2008.04.003"},{"issue":"11","key":"CIT0059","doi-asserted-by":"crossref","first-page":"4049","DOI":"10.4049\/jimmunol.136.11.4049","volume":"136","author":"Folks T","year":"1986","journal-title":"J Immunol"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1111\/j.1472-8206.2005.00324.x"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1517\/17425240903081705"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkl379"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20032069"},{"issue":"5","key":"CIT0064","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1038\/8394","volume":"5","author":"Finzi D","year":"1999","journal-title":"Nature Med"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkf161"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dki308"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1016\/j.clpt.2005.04.004"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0282(1999)51:1<51::AID-BIP6>3.0.CO;2-U"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-200001070-00019"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1258\/095646207781568493"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-200009080-00009"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.12.4903-4910.2005"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1067\/mcp.2001.119212"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.2001.00113.x"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1097\/00008571-200210000-00005"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-006-0042-3"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1007\/s10571-004-6926-7"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2007.11.007"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-008-0030-y"},{"key":"CIT0080","doi-asserted-by":"publisher","DOI":"10.1097\/00054725-200608000-00011"},{"key":"CIT0081","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-005-3053-3"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(00)70210-1"},{"issue":"1","key":"CIT0083","first-page":"30","volume":"67","author":"Llorente L","year":"2000","journal-title":"Joint Bone Spine"},{"issue":"1","key":"CIT0084","first-page":"40","volume":"67","author":"Diaz-Borjon A","year":"2000","journal-title":"Joint Bone Spine"},{"key":"CIT0085","doi-asserted-by":"publisher","DOI":"10.2174\/1381612043453117"},{"key":"CIT0086","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2009.01.009"},{"key":"CIT0087","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2002.12.002"},{"key":"CIT0088","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.300.3.1036"},{"key":"CIT0089","doi-asserted-by":"publisher","DOI":"10.1002\/mc.2940130302"},{"key":"CIT0090","doi-asserted-by":"publisher","DOI":"10.1080\/10611860412331285224"},{"key":"CIT0091","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(98)00393-5"},{"key":"CIT0092","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-2498(00)00234-5"},{"issue":"2","key":"CIT0093","first-page":"15","volume":"57","author":"Grub S BH","year":"2001","journal-title":"Eur J Clin Pharmacol"},{"key":"CIT0094","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200105150-00021"},{"key":"CIT0095","doi-asserted-by":"publisher","DOI":"10.1046\/j.0306-5251.2001.01452.x"},{"key":"CIT0096","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.7.3473"},{"key":"CIT0097","doi-asserted-by":"publisher","DOI":"10.1023\/A:1012244520615"},{"key":"CIT0098","doi-asserted-by":"publisher","DOI":"10.1067\/mcp.2001.117412"},{"key":"CIT0099","doi-asserted-by":"publisher","DOI":"10.1177\/0091270008319329"},{"key":"CIT0100","doi-asserted-by":"publisher","DOI":"10.1023\/B:PHAM.0000029276.21063.0b"},{"key":"CIT0101","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2005.06.051"},{"key":"CIT0102","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2008.01661.x"},{"key":"CIT0103","doi-asserted-by":"publisher","DOI":"10.1007\/s00210-008-0312-9"},{"key":"CIT0104","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-006-0133-z"},{"key":"CIT0105","doi-asserted-by":"publisher","DOI":"10.1097\/00008571-200311000-00001"},{"key":"CIT0106","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e31818d8f28"}],"container-title":["Expert Opinion on Drug Metabolism &amp; Toxicology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/17425251003610640","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T21:06:31Z","timestamp":1685567191000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1517\/17425251003610640"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4,19]]},"references-count":105,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2010,2,18]]},"published-print":{"date-parts":[[2010,5]]}},"alternative-id":["10.1517\/17425251003610640"],"URL":"https:\/\/doi.org\/10.1517\/17425251003610640","relation":{},"ISSN":["1742-5255","1744-7607"],"issn-type":[{"value":"1742-5255","type":"print"},{"value":"1744-7607","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,4,19]]}}}