{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T02:03:44Z","timestamp":1778551424792,"version":"3.51.4"},"reference-count":74,"publisher":"Informa UK Limited","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Expert Opinion on Drug Discovery"],"published-print":{"date-parts":[[2008,1]]},"DOI":"10.1517\/17460441.3.1.131","type":"journal-article","created":{"date-parts":[[2007,12,19]],"date-time":"2007-12-19T13:19:10Z","timestamp":1198070350000},"page":"131-143","source":"Crossref","is-referenced-by-count":19,"title":["Seliciclib, a cell-cycle modulator that acts through the inhibition of cyclin-dependent kinases"],"prefix":"10.1517","volume":"3","author":[{"given":"Robert C","family":"Jackson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna L","family":"Barnett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven J","family":"McClue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon R","family":"Green","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2007,12,19]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1038\/312596a0"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1126\/science.274.5293.1672"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(95)90385-2"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.8.4325"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.24.14.6268-6277.2004"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1997.t01-2-00527.x"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1021\/jm960666x"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1997.0518a.x"},{"key":"CIT0009","first-page":"623","volume":"4","author":"Fischer","year":"2001","journal-title":"Currt Opin Drug Discov and Dev"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.10738"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1016\/0962-8924(96)10034-9"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.46.8.2470-2476.2002"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20021535"},{"key":"CIT0017","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1158\/1535-7163.1427.3.11","volume":"3","author":"Fry","year":"2004","journal-title":"Mol Cancer Ther"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2004.01.009"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-03-0110"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1203103"},{"key":"CIT0022","first-page":"95","volume":"21","author":"Mihara","year":"2002","journal-title":"Int J Oncol"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdi217"},{"key":"CIT0024","first-page":"4529","volume":"6","author":"Raynaud","year":"2000","journal-title":"Clin Cancer Res"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-1276"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.21010"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1038\/ng1232"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2005.06.001"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2003.09.024"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(03)00645-7"},{"key":"CIT0031","author":"Su","year":"2004","journal-title":"Sci STKE"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1016\/S1535-6108(03)00053-9"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1016\/S0962-8924(03)00148-X"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1016\/S1535-6108(03)00084-9"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M102306200"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2001-2-10-research0041"},{"key":"CIT0037","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1158\/1535-7163.861.3.7","volume":"3","author":"Lu","year":"2004","journal-title":"Mol Cancer Ther"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.03.7689"},{"key":"CIT0039","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0026-895X(24)12306-1","volume":"60","author":"Ljungman","year":"2001","journal-title":"Mol Pharm"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-0233"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-07-2713"},{"key":"CIT0042","first-page":"3527","volume":"8","author":"Raje","year":"2002","journal-title":"Clin Cancer Res"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1204412"},{"key":"CIT0044","volume":"45","author":"Griffiths","year":"2004","journal-title":"Proc Am Assoc Cancer Res"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-04-2264"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.4161\/cbt.4.1.1462"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2005.02.001"},{"key":"CIT0048","author":"Conroy","journal-title":"Proc Am Assoc Cancer Res"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.5414\/CPP42232"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6603509"},{"key":"CIT0052","author":"Green","year":"2003","journal-title":"Proc Am Assoc Cancer Res"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2004.05.009"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6603220"},{"key":"CIT0055","author":"Green","year":"2004","journal-title":"EORTC-NCI-AACR meeting"},{"key":"CIT0056","first-page":"460","volume":"46","author":"Frame","year":"2005","journal-title":"Proc Am Assoc Cancer Res."},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.175.2.985"},{"key":"CIT0058","author":"Hsieh","year":"2006","journal-title":"R"},{"key":"CIT0059","first-page":"4610","volume":"56","author":"Wang","year":"1996","journal-title":"Cancer Res"},{"key":"CIT0060","first-page":"414","volume":"25","author":"Baba","year":"2001","journal-title":"Cancer Detect Prev"},{"key":"CIT0061","first-page":"273","volume":"27","author":"Coley","year":"2007","journal-title":"Anticancer Res"},{"key":"CIT0062","first-page":"1862","volume":"62","author":"Voojis","year":"2002","journal-title":"Cancer Res"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1207299"},{"key":"CIT0064","author":"Fiebig","year":"2003","journal-title":"Clin Cancer Res"},{"key":"CIT0065","author":"Frame","year":"2007","journal-title":"Proc Amer Assoc Cancer Res"},{"key":"CIT0066","author":"Fleming","year":"2006","journal-title":"Proc Am Assoc Cancer Res"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-3964"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1210166"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1677\/ERC-06-0003"},{"key":"CIT0070","author":"Wesierska-Gadek","journal-title":"J Cell Biochem"},{"key":"CIT0071","first-page":"2513","volume":"63","author":"Maggiorella","year":"2003","journal-title":"Cancer Res"},{"key":"CIT0072","first-page":"695","volume":"1","author":"Wu","year":"2002","journal-title":"Mol Cancer Ther"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2002.11.126"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkf227"},{"key":"CIT0075","doi-asserted-by":"crossref","first-page":"F515","DOI":"10.1152\/ajprenal.2000.278.4.F515","volume":"278","author":"Shankland","year":"2000","journal-title":"Am J Physiol Renal Physiol"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1038\/nm1468"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1002\/art.22593"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1038\/nature05348"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.4161\/cc.3.3.706"}],"container-title":["Expert Opinion on Drug Discovery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1517\/17460441.3.1.131","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T05:44:29Z","timestamp":1737697469000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1517\/17460441.3.1.131"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,12,19]]},"references-count":74,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2007,12,19]]},"published-print":{"date-parts":[[2008,1]]}},"alternative-id":["10.1517\/17460441.3.1.131"],"URL":"https:\/\/doi.org\/10.1517\/17460441.3.1.131","relation":{},"ISSN":["1746-0441","1746-045X"],"issn-type":[{"value":"1746-0441","type":"print"},{"value":"1746-045X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,12,19]]}}}