{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T20:30:15Z","timestamp":1768422615481,"version":"3.49.0"},"reference-count":18,"publisher":"Maad Rayan Publishing Company","issue":"2","content-domain":{"domain":["mejdd.org"],"crossmark-restriction":false},"short-container-title":["Middle East J Dig Dis"],"abstract":"<jats:p>BACKGROUND  Gastrointestinal (GI) bleeding is one of the most prevalent internal medical emergencies. Despite using several methods of treatment, effective treatment cannot be achieved in some patients. Hemostasis powder\u00ae is a mineral-herbal product. This emulsion was able to coagulate blood in, in vitro studies and also was effective in the treatment of mucosal and cutaneous bleeding in animal studies, without any toxicity. We decided to compare its effect on the treatment of human GI bleeding with the other common method for treatment of GI bleeding \"argon plasma coagulation plus epinephrine injection\" in a pilot randomized clinical trial.  METHODS  The patients with GI bleeding who were admitted to the emergency wards of Ghaem and Imam-Reza Hospitals in Mashhad were randomized to treatment with Hemostasis powder\u00ae or \"argon plasma coagulation plus epinephrine injection\" method, with randomized doctors, after complete testimonial sheet. The patients underwent re-endoscopy to evaluate the ulcers 3 days later, and were under observation for 3 months. After achieving the number of patients that was planned (20 patients), all data were entered to SPSS software version 20 and were analyzed with parametric and non-parametric tests.  RESULTS  The treatment success was 95% in both groups. There was no complication after treatment of GI bleeding in the two groups after 3 months. No rebreeding was reported in Hemostasis powder\u00ae group but 10 % was reported in \"argon plasma coagulation plus epinephrine injection\" group.  CONCLUSION  It seems that if the successful results occur in the future complimentary studies, Hemostasis powder\u00ae can be used as a new, effective, available, and inexpensive measure in the treatment of GI bleeding and also in the GI bleedings that cannot be treated with common available methods.<\/jats:p>","DOI":"10.15171\/mejdd.2018.132","type":"journal-article","created":{"date-parts":[[2019,6,8]],"date-time":"2019-06-08T09:17:39Z","timestamp":1559985459000},"page":"84-89","update-policy":"https:\/\/doi.org\/10.15171\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The Effect of Hemostasis Powder\u00ae on Treatment of Bleeding from Benign Ulcers of Upper Gastrointestinal Tract; A Pilot Study"],"prefix":"10.34172","volume":"11","author":[{"given":"Jamshid","family":"Vafaeimanesh","sequence":"first","affiliation":[{"name":"Associate professor, Gastroenterology and Hepatology Disease Research Center, Qom University of Medical Sciences, Qom, Iran"},{"name":"Gastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan","family":"Rakhshandeh","sequence":"additional","affiliation":[{"name":"Pharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Pourakbar","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyed MousalReza","family":"Hosseini","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"20123","published-online":{"date-parts":[[2019,2,14]]},"reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1310006"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2002.06037.x"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1256125"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4733.2007.00208.x"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2004.30272"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2006.00518.x"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1080\/00365520510015809"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-152-2-201001190-00009"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2007.123976"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0706113"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.4291\/wjgp.v5.i3.284"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1097\/MBC.0000000000000482"},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1256311"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/759436"},{"key":"R15","doi-asserted-by":"publisher","DOI":"10.1055\/s-0042-116148"},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.13617"},{"key":"R17","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2013.03.006"},{"key":"R18","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000001967"}],"container-title":["Middle East Journal of Digestive Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/mejdd.org\/index.php\/mejdd\/article\/download\/1926\/2101","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/mejdd.org\/index.php\/mejdd\/article\/download\/1926\/2101","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,25]],"date-time":"2020-03-25T12:08:01Z","timestamp":1585138081000},"score":1,"resource":{"primary":{"URL":"http:\/\/mejdd.org\/index.php\/mejdd\/article\/view\/1926"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,14]]},"references-count":18,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2019,4]]}},"URL":"https:\/\/doi.org\/10.15171\/mejdd.2018.132","relation":{},"ISSN":["2008-5249"],"issn-type":[{"value":"2008-5249","type":"print"}],"subject":[],"published":{"date-parts":[[2019,2,14]]},"assertion":[{"value":"Iranian Association of Gastroenterology and Hepatology","name":"journal_owner","label":"Journal Owner"},{"value":"Iranian Association of Gastroenterology and Hepatology","name":"journal_publisher","label":"Journal Publisher"}]}}