{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T16:26:11Z","timestamp":1762014371460,"version":"build-2065373602"},"reference-count":33,"publisher":"Maad Rayan Publishing Company","issue":"2","content-domain":{"domain":["mejdd.org"],"crossmark-restriction":false},"short-container-title":["Middle East J Dig Dis"],"abstract":"<jats:p>Guillain-Barr\u00e9 syndrome (GBS) is an acute monophasic immune-mediated polyradiculoneuropathy. Here, we report a case of a young man with acute motor axonal neuropathy (AMAN) subtype of GBS having hepatitis A virus (HAV) infection.  A 30-year-old man with icterus was referred to emergency center of Razi Hospital. He complained of flu-like symptoms 10 days before the onset of icterus. Also, he suffered from gradual fatigue and weakness with dark urine. He experienced neurological symptoms of muscle paralysis (ascending from the legs to hands). Neurological consultant suspected GBS at the first step based on clinical examinations. He was candidate for five sessions of plasmapheresis. The ultrasonography revealed liver span 166 mm, which was greater than the normal range, with normal parenchymal echo. The gallbladder wall was thicker than normal and gallstone with lesion was not seen in different conditions. He was discharged after total improvement of neurological symptoms and muscular power. In addition, the results of International normalized ratio (INR), partial thromboplastin time (PTT), prothrombin time (PT), alkaline phosphatase (ALK), alanine aminotransferase (ALT) , aspartate aminotransferase (AST), bilirubin total and direct (Bil T, D) tests were normal after 2-month follow-up.  Although, acute viral infections such as hepatitis E virus (HEV) is common in patients with GBS; the possibility of HAV infection in patients with its risk factor should not be neglected. <\/jats:p>","DOI":"10.15171\/mejdd.2018.136","type":"journal-article","created":{"date-parts":[[2019,6,8]],"date-time":"2019-06-08T09:18:51Z","timestamp":1559985531000},"page":"110-115","update-policy":"https:\/\/doi.org\/10.15171\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A 30-Year-Old Man with Acute Motor Axonal Neuropathy Subtype of Guillain-Barr\u00e9 Syndrome Having Hepatitis A Virus Infection"],"prefix":"10.34172","volume":"11","author":[{"given":"Alireza","family":"Samadi","sequence":"first","affiliation":[{"name":"Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fariborz","family":"Mansour-Ghanaei","sequence":"additional","affiliation":[{"name":"Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farahnaz","family":"Joukar","sequence":"additional","affiliation":[{"name":"Caspian Digestive Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Mavaddati","sequence":"additional","affiliation":[{"name":"Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iman","family":"Sufi Afshar","sequence":"additional","affiliation":[{"name":"Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"20123","published-online":{"date-parts":[[2019,2,21]]},"reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2013.01.005"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2014.06.013"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.4103\/ijmr.IJMR_995_14"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-282X2004000100006"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1086\/513793"},{"key":"R6","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1097\/00019052-200110000-00009","article-title":"Epidemiology of the Guillain-Barr\u00e9 syndrome","volume":"14","author":"Govoni V","year":"2001","journal-title":"Curr Opin Neurol"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1159\/000184748"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.901940"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1557429"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.4103\/0972-2327.82793"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.904925"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.902668"},{"key":"R13","first-page":"544","article-title":"Report of five children with Guillain-Barr\u00e9 syndrome following a nationwide oral polio vaccine campaign in Turkey","volume":"51","author":"Anlar O","year":"2003","journal-title":"Neurol India"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2013.28.12.1839"},{"key":"R15","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.46.1.96"},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.1007\/s004310051086"},{"key":"R17","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.1890210303"},{"key":"R18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2010.02.016"},{"key":"R19","doi-asserted-by":"publisher","DOI":"10.1258\/004947506778604706"},{"key":"R20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2010.09.015"},{"key":"R21","first-page":"228","article-title":"A case of acute hepatitis A complicated by Guillain-Barre syndrome","volume":"13","author":"Bae YJ","year":"2007","journal-title":"Korean J Hepatol"},{"key":"R22","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.33.799"},{"key":"R23","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70215-1"},{"key":"R24","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/118.3.597"},{"key":"R25","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000003257"},{"key":"R26","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2014.121"},{"key":"R27","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000081231.08914.A1"},{"key":"R28","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-006-0548-4"},{"key":"R29","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/118.3.577"},{"key":"R30","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-1331.2003.00683.x"},{"key":"R31","first-page":"92","article-title":"A child with Guillain-Barre syndrome caused by acute hepatitis a infection","volume":"41","author":"Kocabas E","year":"2004","journal-title":"Indian Pediatr"},{"key":"R32","doi-asserted-by":"publisher","DOI":"10.1177\/0883073809332695"},{"key":"R33","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-018-2959-2"}],"container-title":["Middle East Journal of Digestive Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/mejdd.org\/index.php\/mejdd\/article\/download\/2040\/2105","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/mejdd.org\/index.php\/mejdd\/article\/download\/2040\/2105","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,25]],"date-time":"2020-03-25T12:08:37Z","timestamp":1585138117000},"score":1,"resource":{"primary":{"URL":"http:\/\/mejdd.org\/index.php\/mejdd\/article\/view\/2040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,21]]},"references-count":33,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2019,4]]}},"URL":"https:\/\/doi.org\/10.15171\/mejdd.2018.136","relation":{},"ISSN":["2008-5249"],"issn-type":[{"type":"print","value":"2008-5249"}],"subject":[],"published":{"date-parts":[[2019,2,21]]},"assertion":[{"value":"Iranian Association of Gastroenterology and Hepatology","name":"journal_owner","label":"Journal Owner"},{"value":"Iranian Association of Gastroenterology and Hepatology","name":"journal_publisher","label":"Journal Publisher"}]}}