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A 13-member expert and community advisory board guided six adaptation steps, prioritizing behavioral outcomes, objectives, and KIU!\u2019s core theoretical determinants. The resulting intervention includes a universal HIV module, a tailored PrEP module based on users\u2019 PrEP experience, and a relationship module for participants who are single, monogamous, or in open\/polyamorous relationships. Usability testing with 15 end users demonstrated high acceptability, engagement, and usability. Findings suggest that adapting multisession DHIs into single-session formats can preserve core intervention mechanisms while improving reach to populations and settings where multisession delivery is infeasible. We provide recommendations for future adaptation.<\/jats:p>","DOI":"10.1521\/aeap.2026.38.5.347","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T14:24:11Z","timestamp":1791383051000},"page":"347-365","source":"Crossref","is-referenced-by-count":0,"title":["An Adapted Intervention Mapping Approach to Scaling Digital HIV Care Through Single-Session Design"],"prefix":"10.1521","volume":"38","author":[{"given":"Juan Pablo","family":"Zapata","sequence":"first","affiliation":[{"name":"Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois."},{"name":"Impact Institute, Northwestern University, Chicago."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyssa N.","family":"Gorkin","sequence":"additional","affiliation":[{"name":"Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Psychology, Institute for Relationship Science, University of Denver, Denver, Colorado."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alithia","family":"Zamantakis","sequence":"additional","affiliation":[{"name":"Impact Institute, Northwestern University, Chicago."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rana","family":"Saber","sequence":"additional","affiliation":[{"name":"Research Application Design and Developmental Core, Northwestern University, Chicago."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica Lee","family":"Schleider","sequence":"additional","affiliation":[{"name":"Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois."},{"name":"The Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Mustanski","sequence":"additional","affiliation":[{"name":"Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"377","reference":[{"key":"ref1","first-page":"61","volume":"1","author":"Alghamdi A.","year":"2013","journal-title":"International Review of Basic and Applied Sciences"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1080\/10447318.2021.1938391"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1177\/109019819802500502"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/COH.0000000000000721"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1177\/1357633X16639186"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.2196\/35693"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1186\/s13012-020-01069-w"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.1343"},{"key":"ref9","first-page":"21","volume-title":"Emerging theories in health promotion practice and research","author":"Fisher J. 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