{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T21:36:43Z","timestamp":1740173803452,"version":"3.37.3"},"reference-count":55,"publisher":"Society for Neuroscience","issue":"4","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":184,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"crossref","award":["DFG BI 195\/69-1"],"award-info":[{"award-number":["DFG BI 195\/69-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["eNeuro"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Emotions have an important survival function. Vast amounts of research have demonstrated how affect-related changes in physiology promote survival by effecting short-term and long-term changes in adaptive behavior. However, if emotions truly serve such an inherent function, they should be pervasive across species and be established early in life. Here, using electroencephalographic (EEG) brain activity we sought to characterize core neurophysiological features underlying affective function at the emergence of emotional expression [i.e., at the developmental age when human infants start to show reliable stimulus-elicited emotional states (4\u20136\u2009months)]. Using an approach that eschews traditional EEG frequency band delineations (like theta, alpha), we demonstrate that negative emotional states induce a strong right hemispheric increase in the prominence of the resonant frequency (\u223c5\u20136\u2009Hz) in the infant frontal EEG. Increased rightward asymmetry was strongly correlated with increased heart rate responses to emotionally negative states compared with neutral states. We conclude that functional frontal asymmetry is a key component of emotional processing and suggest that the rightward asymmetry in prominence of the resonant frequency during negative emotional states might reflect functional asymmetry in the central representation of anatomically driven asymmetry in the autonomic nervous system. Our findings indicate that the specific mode hallmarking emotional processing in the frontal cortex is established in parallel with the emergence of stable emotional states very early during development, despite the well known protracted maturation of frontal cortex.<\/jats:p>","DOI":"10.1523\/eneuro.0042-20.2020","type":"journal-article","created":{"date-parts":[[2020,8,17]],"date-time":"2020-08-17T21:50:48Z","timestamp":1597701048000},"page":"ENEURO.0042-20.2020","source":"Crossref","is-referenced-by-count":1,"title":["Affective Cortical Asymmetry at the Early Developmental Emergence of Emotional Expression"],"prefix":"10.1523","volume":"7","author":[{"given":"Elaina","family":"Bolinger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong-Viet V.","family":"Ngo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa","family":"Kock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk T.","family":"Wassen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamara","family":"Matuz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niels","family":"Birbaumer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1847-6248","authenticated-orcid":false,"given":"Jan","family":"Born","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina","family":"Zinke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"393","published-online":{"date-parts":[[2020,8,17]]},"reference":[{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-8760(01)00194-5"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.2","doi-asserted-by":"publisher","DOI":"10.1159\/000447640"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.bandc.2015.02.001"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.4","doi-asserted-by":"publisher","DOI":"10.1111\/psyp.12866"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.5","doi-asserted-by":"publisher","DOI":"10.1037\/0735-7044.117.1.11"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.6","doi-asserted-by":"publisher","DOI":"10.1111\/1469-8986.00011"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsycho.2004.03.002"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2005.10.005"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.9","doi-asserted-by":"publisher","DOI":"10.1126\/science.7146906"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.10","doi-asserted-by":"publisher","DOI":"10.2307\/1131357"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.11","doi-asserted-by":"publisher","DOI":"10.1002\/dev.20612"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.12","doi-asserted-by":"publisher","DOI":"10.1037\/\/0012-1649.23.2.233"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.13","doi-asserted-by":"publisher","DOI":"10.1037\/0012-1649.24.2.230"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.14","doi-asserted-by":"crossref","unstructured":"Fox NA , Henderson HA (2007) Considerations in studying emotion in infants and children. In: Handbook of emotion elicitation and assessment (Coan JA, Allen JJB eds), p 349. Oxford: Oxford UP.","DOI":"10.1093\/oso\/9780195169157.003.0022"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.15","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2015.09.034"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.16","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-013-1926-4"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.17","doi-asserted-by":"publisher","DOI":"10.1093\/scan\/nsv017"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.18","doi-asserted-by":"publisher","DOI":"10.1002\/dev.21212"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.19","unstructured":"Goldsmith H , Rothbart M (1996) Prelocomotor and locomotor laboratory temperament assessment battery (Lab-TAB; version 3.0, technical manual). Madison, WI: Department of Psychology, University of Wisconsin."},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.20","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2012.07.006"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.21","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsycho.2009.08.010"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.22","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3869"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.23","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpsc.2019.12.003"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.24","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2010.00186"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.25","doi-asserted-by":"publisher","DOI":"10.1002\/dev.21336"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.26","doi-asserted-by":"publisher","DOI":"10.1023\/A:1025197101496"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.27","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1825"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.28","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2554"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.29","doi-asserted-by":"publisher","DOI":"10.1177\/0165025415576816"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.30","doi-asserted-by":"publisher","DOI":"10.1016\/j.kjms.2013.11.001"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.31","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.03.007"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.32","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0022694"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.33","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpsycho.2014.09.008"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.34","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-2457(02)00163-3"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.35","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)80309-9"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.36","first-page":"328","article-title":"The interactive development of social smiling","volume":"35","year":"2007","journal-title":"Adv Child Dev Behav"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.37","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2015.06.042"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.38","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0093728"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.39","doi-asserted-by":"publisher","DOI":"10.1016\/j.infbeh.2004.03.002"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.40","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.42.9.1727"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.41","doi-asserted-by":"publisher","DOI":"10.1037\/0012-1649.28.6.1115"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.42","doi-asserted-by":"publisher","DOI":"10.1207\/s15327752jpa8701_09"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.43","doi-asserted-by":"publisher","DOI":"10.1080\/00223891.2013.841171"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.44","doi-asserted-by":"publisher","DOI":"10.1080\/87565641.2011.614663"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.45","first-page":"53","article-title":"Patterns of fear development during infancy","volume":"16","year":"1970","journal-title":"Merrill Palmer Quart"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.46","doi-asserted-by":"publisher","DOI":"10.1016\/j.infbeh.2012.05.002"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.47","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1508345112"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.48","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpsycho.2016.11.005"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.49","doi-asserted-by":"publisher","DOI":"10.1097\/00001163-200304000-00005"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.50","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0904031106"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.51","doi-asserted-by":"publisher","DOI":"10.1111\/1467-9280.00240"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.52","doi-asserted-by":"publisher","DOI":"10.1098\/rsta.2015.0176"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.53","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2017.28"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.54","doi-asserted-by":"publisher","DOI":"10.1007\/s10548-015-0448-0"},{"key":"2023041302145636000_7.4.ENEURO.0042-20.2020.55","doi-asserted-by":"publisher","DOI":"10.1111\/desc.12562"}],"container-title":["eneuro"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1523\/ENEURO.0042-20.2020","content-type":"unspecified","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1523\/ENEURO.0042-20.2020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,11]],"date-time":"2024-08-11T23:15:24Z","timestamp":1723418124000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eneuro.org\/lookup\/doi\/10.1523\/ENEURO.0042-20.2020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":55,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,8,27]]},"published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.1523\/ENEURO.0042-20.2020"],"URL":"https:\/\/doi.org\/10.1523\/eneuro.0042-20.2020","relation":{},"ISSN":["2373-2822"],"issn-type":[{"type":"electronic","value":"2373-2822"}],"subject":[],"published":{"date-parts":[[2020,7]]}}}