{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T03:04:11Z","timestamp":1789873451090,"version":"4.0.1"},"reference-count":143,"publisher":"Society for Neuroscience","issue":"8","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"vor","delay-in-days":192,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000027","name":"HHS | NIH | National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["R01 016022"],"award-info":[{"award-number":["R01 016022"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"HHS | NIH | National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["R01 038890"],"award-info":[{"award-number":["R01 038890"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"HHS | NIH | National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["R01 056113"],"award-info":[{"award-number":["R01 056113"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009979","name":"GMU | College of Science, George Mason University","doi-asserted-by":"publisher","award":["Presidential Scholarship"],"award-info":[{"award-number":["Presidential Scholarship"]}],"id":[{"id":"10.13039\/100009979","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009979","name":"GMU | College of Science, George Mason University","doi-asserted-by":"publisher","award":["Dissertation Completion Grant"],"award-info":[{"award-number":["Dissertation Completion Grant"]}],"id":[{"id":"10.13039\/100009979","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["eNeuro"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Estradiol, a female sex hormone and the predominant form of estrogen, has diverse effects throughout the brain including in learning and memory. Estradiol modulates several types of learning that depend on the dorsomedial striatum (DMS), a subregion of the basal ganglia involved in goal-directed learning, cued action-selection, and motor skills. A cellular basis of learning is synaptic plasticity, and the presence of extranuclear estradiol receptors ER\u03b1, ER\u03b2, and G-protein-coupled estrogen receptor (GPER) throughout the DMS suggests that estradiol may influence rapid cellular actions including those involved in plasticity. To test whether estradiol affects synaptic plasticity in the DMS, corticostriatal long-term potentiation (LTP) was induced using theta-burst stimulation (TBS) in\n                    <jats:italic>ex vivo<\/jats:italic>\n                    brain slices from intact male and female C57BL\/6 mice. Extracellular field recordings showed that female mice in the diestrous stage of the estrous cycle exhibited LTP similar to male mice, while female mice in estrus did not exhibit LTP. Furthermore, antagonists of ER\u03b1 or GPER rescued LTP in estrous females and agonists of ER\u03b1 or GPER reduced LTP in diestrous females. In males, activating ER\u03b1 but not GPER reduced LTP. These results uncover an inhibitory action of estradiol receptors on cellular learning in the DMS and suggest a cellular mechanism underlying the impairment in certain types of DMS-based learning observed in the presence of high estradiol. Because of the dorsal striatum\u2019s role in substance use disorders, these findings may provide a mechanism underlying an estradiol-mediated progression from goal-directed to habitual drug use.\n                  <\/jats:p>","DOI":"10.1523\/eneuro.0071-23.2023","type":"journal-article","created":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T13:50:14Z","timestamp":1690206614000},"page":"ENEURO.0071-23.2023","source":"Crossref","is-referenced-by-count":13,"title":["Estradiol Receptors Inhibit Long-Term Potentiation in the Dorsomedial Striatum"],"prefix":"10.1523","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6456-6156","authenticated-orcid":false,"given":"Valerie J.","family":"Lewitus","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim T.","family":"Blackwell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"393","published-online":{"date-parts":[[2023,7,24]]},"reference":[{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.1","doi-asserted-by":"crossref","first-page":"943343","DOI":"10.3389\/fendo.2022.943343","article-title":"Deciphering of a putative GPER recognition domain in ER\u03b1 and ER\u03b136","volume":"13","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2009.05.013"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.3","doi-asserted-by":"publisher","DOI":"10.1210\/en.2012-1458"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.4","first-page":"77","article-title":"Estrogen receptor beta and 2-arachidonoylglycerol mediate the suppressive effects of estradiol on frequency of postsynaptic currents in gonadotropin-releasing hormone neurons of metestrous mice: an acute slice electrophysiological study","volume":"10","year":"2016","journal-title":"Front Cell Neurosci"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2005.08.061"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.6","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(94)91229-7"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.7","doi-asserted-by":"publisher","DOI":"10.1002\/syn.890050211"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.8","doi-asserted-by":"publisher","DOI":"10.31887\/DCNS.2016.18.4\/jbecker"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.9","doi-asserted-by":"publisher","DOI":"10.1016\/0166-4328(86)90044-6"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.10","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-3057(99)00091-X"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.yfrne.2007.07.003"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.12","doi-asserted-by":"publisher","DOI":"10.1016\/0091-3057(87)90476-X"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.13","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.23963"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1986.tb07972.x"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.15","first-page":"527","article-title":"Synaptic organisation of the basal ganglia","volume":"196 [Pt 4]","year":"2000","journal-title":"J Anat"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.16","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2015.04.006"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.17","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.12-11-04224.1992"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.18","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.20-22-08443.2000"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.19","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms13877"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.20","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1037\/pha0000142","article-title":"Differences in mood and cortisol by menstrual phase during acute smoking abstinence: a within-subject comparison","volume":"25","year":"2017","journal-title":"Exp Clin Psychopharmacol"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.21","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(93)91225-H"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.22","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2013.06.013"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.23","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2014.04.002"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.24","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0169-328X(01)00217-0","article-title":"Group I metabotropic glutamate receptor activation increases phosphorylation of cAMP response element-binding protein, Elk-1, and extracellular signal-regulated kinases in rat dorsal striatum","volume":"94","year":"2001","journal-title":"Brain Res Mol Brain Res"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.25","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2012.02.024"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.26","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/aps.2010.199","article-title":"Alteration of synaptic plasticity in rat dorsal striatum induced by chronic ethanol intake and withdrawal via ERK pathway","volume":"32","year":"2011","journal-title":"Acta Pharmacol Sin"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.27","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2004.06.001"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.28","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2005.06.004"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.29","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0152138"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.30","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(89)91266-3"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.31","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2011.11.010"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.32","doi-asserted-by":"publisher","DOI":"10.1210\/en.2012-1061"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.33","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2016.04.004"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.34","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1152\/jn.1999.81.2.925","article-title":"17\u03b2-estradiol enhances NMDA receptor-mediated EPSPs and long-term potentiation","volume":"81","year":"1999","journal-title":"J Neurophysiol"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.35","doi-asserted-by":"publisher","DOI":"10.1093\/ntr\/ntu183"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.36","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0166-4328(01)00255-8","article-title":"High levels of estradiol disrupt conditioned place preference learning, stimulus response learning and reference memory but have limited effects on working memory","volume":"126","year":"2001","journal-title":"Behav Brain Res"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.37","doi-asserted-by":"publisher","DOI":"10.1038\/nn832"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.38","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2011.06.078"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.39","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms3264"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.40","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2010.08.012"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.41","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2003.11.021"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.42","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2014.12.056"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.43","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00115.2013"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.44","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4415-14.2015"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.45","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1037\/adb0000576","article-title":"Menstrual cycle phase, alcohol consumption, alcohol cravings, and mood among women in outpatient treatment for alcohol use disorder","volume":"34","year":"2020","journal-title":"Psychol Addict Behav"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.46","doi-asserted-by":"publisher","DOI":"10.1042\/bj20021698"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.47","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2007.10.005"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.48","doi-asserted-by":"publisher","DOI":"10.1002\/syn.20221"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.49","doi-asserted-by":"crossref","unstructured":"Hussain D , Cossette MP , Brake WG (2016) High oestradiol replacement reverses response memory bias in ovariectomised female rats regardless of dopamine levels in the dorsal striatum. J Neuroendocrinol. Advance online publication. Retrieved February 29, 2016. https:\/\/doi.org\/10.1111\/jne.12375.","DOI":"10.1111\/jne.12375"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.50","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2010.05.013"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.51","doi-asserted-by":"publisher","DOI":"10.1210\/en.2012-1121"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.52","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1300778"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.53","doi-asserted-by":"publisher","DOI":"10.1210\/en.2015-1959"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.54","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-10704-0"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.55","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2013.00149"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.56","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.1971.0102"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.57","doi-asserted-by":"publisher","DOI":"10.1152\/jn.2001.85.1.117"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.58","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1002953"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.59","doi-asserted-by":"publisher","DOI":"10.1037\/0735-7044.116.3.411"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.60","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2015.06.017"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.61","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2004.01.005"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.62","doi-asserted-by":"crossref","first-page":"993552","DOI":"10.3389\/fendo.2022.993552","article-title":"17\u03b2-estradiol does not have a direct effect on the function of striatal cholinergic interneurons in adult mice in vitro","volume":"13","year":"2023","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.63","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2959-05.2005"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.64","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2008.11.005"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.65","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00264.2019"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.66","doi-asserted-by":"publisher","DOI":"10.1159\/000050126"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.67","first-page":"663","article-title":"Impact of repeated methamphetamine pretreatment on intravenous self-administration of the drug in males and estrogenized or non-estrogenized ovariectomized female rats","volume":"30","year":"2009","journal-title":"Neuroendocrinol Lett"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.68","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.22475"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.69","doi-asserted-by":"publisher","DOI":"10.1113\/JP270045"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.70","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S0169-328X(98)00279-4","article-title":"Expression of aromatase in the embryonic and postnatal mouse striatum","volume":"63","year":"1998","journal-title":"Brain Res Mol Brain Res"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.71","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(99)00815-0"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.72","doi-asserted-by":"publisher","DOI":"10.1037\/1064-1297.15.5.461"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.73","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0807749105"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.74","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.28.19677"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.75","doi-asserted-by":"publisher","DOI":"10.3389\/fnsys.2019.00028"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.76","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2010.01.008"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.77","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1152\/jn.1993.69.4.1236","article-title":"Properties of a presynaptic metabotropic glutamate receptor in rat neostriatal slices","volume":"69","year":"1993","journal-title":"J Neurophysiol"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.78","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1970-18.2019"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.79","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2018.04.007"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.80","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a005710"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.81","doi-asserted-by":"publisher","DOI":"10.1007\/s002130050979"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.82","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1300.001"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.83","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.25.112701.142758"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.84","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.24552"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.85","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4360-04.2005"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.86","doi-asserted-by":"publisher","DOI":"10.1016\/j.cobeha.2018.03.007"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.87","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.16-02-00595.1996"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.88","doi-asserted-by":"publisher","DOI":"10.1016\/j.yfrne.2012.07.003"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.89","doi-asserted-by":"publisher","DOI":"10.1159\/000126507"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.90","doi-asserted-by":"publisher","DOI":"10.1101\/lm.2123811"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.91","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2012.104"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.92","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2010.08.017"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.93","doi-asserted-by":"publisher","DOI":"10.1006\/nlme.1996.0007"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.94","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.09-05-01465.1989"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.95","doi-asserted-by":"publisher","DOI":"10.1530\/REP-07-0512"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.96","doi-asserted-by":"publisher","DOI":"10.1152\/jn.2000.84.3.1422"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.97","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2012.82"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.98","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1522150112"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.99","doi-asserted-by":"crossref","first-page":"19","DOI":"10.3109\/10826088909047272","article-title":"Telescoping of alcoholism in women alcoholics","volume":"24","year":"1989","journal-title":"Int J Addict"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.100","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1210\/en.2015-1616","article-title":"Estrogen receptor-selective agonists modulate learning in female rats in a dose- and task-specific manner","volume":"157","year":"2016","journal-title":"Endocrinology"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.101","doi-asserted-by":"publisher","DOI":"10.1210\/en.2010-0715"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.102","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00263.2018"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.103","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00157.2020"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.104","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2021.104949"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.105","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2021.108491"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.106","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2007.09.015"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.107","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.nlm.2013.08.018","article-title":"Estradiol and striatal dopamine receptor antagonism influence memory system bias in the female rat","volume":"106","year":"2013","journal-title":"Neurobiol Learn Mem"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.108","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-6080(02)00045-X"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.109","doi-asserted-by":"publisher","DOI":"10.1038\/35092560"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.110","doi-asserted-by":"publisher","DOI":"10.1016\/0361-9230(90)90064-7"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.111","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.23-37-11641.2003"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.112","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4647-08.2009"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.113","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2016.05.049"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.114","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0313-14.2014"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.115","doi-asserted-by":"publisher","DOI":"10.1111\/ejn.12971"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.116","doi-asserted-by":"crossref","first-page":"108816","DOI":"10.1016\/j.drugalcdep.2021.108816","article-title":"The effects of chronic estradiol treatment on opioid self-administration in intact female rats","volume":"225","year":"2021","journal-title":"Drug Alcohol Depend"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.117","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5279-05.2006"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.118","doi-asserted-by":"crossref","first-page":"ENEURO.0446-18.2019","DOI":"10.1523\/ENEURO.0446-18.2019","article-title":"Estradiol-induced potentiation of dopamine release in dorsal striatum following amphetamine administration requires estradiol receptors and mGlu5","volume":"6","year":"2019","journal-title":"eNeuro"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.119","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(02)00659-6"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.120","doi-asserted-by":"publisher","DOI":"10.1038\/s41583-020-0362-7"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.121","doi-asserted-by":"publisher","DOI":"10.1016\/j.steroids.2009.11.005"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.122","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2015.00192"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.123","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1046\/j.1469-7580.2003.00180.x","article-title":"The number of cells expressing dopamine D2 receptor mRNA in rat brain caudate putamen is higher in oestrus","volume":"202","year":"2003","journal-title":"J Anat"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.124","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2006.01.004"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.125","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2017.09.004"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.126","doi-asserted-by":"publisher","DOI":"10.1037\/a0012513"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.127","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.yhbeh.2009.07.005","article-title":"Chronic estradiol replacement impairs performance on an operant delayed spatial alternation task in young, middle-aged, and old rats","volume":"56","year":"2009","journal-title":"Horm Behav"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.128","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0801-18.2018"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.129","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2006.04.010"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.130","doi-asserted-by":"crossref","first-page":"100022","DOI":"10.1016\/j.cpnec.2020.100022","article-title":"The effects of menstrual cycle stage and hormonal contraception on alcohol consumption and craving: a pilot investigation","volume":"5","year":"2021","journal-title":"Compr Psychoneuroendocrinol"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.131","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(95)01059-9"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.132","doi-asserted-by":"crossref","first-page":"2737","DOI":"10.1111\/ejn.14506","article-title":"The estrous cycle modulates rat caudate\u2013putamen medium spiny neuron physiology","volume":"52","year":"2020","journal-title":"Eur J Neurosci"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.133","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.12-07-02549.1992"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.134","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(94)90510-X"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.135","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.2008.00818.x"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.136","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2016.10.019"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.137","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2496-04.2004"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.138","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1919"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.139","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2005.04219.x"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.140","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2005.04218.x"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.141","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2261"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.142","doi-asserted-by":"crossref","first-page":"e0191418","DOI":"10.1371\/journal.pone.0191418","article-title":"The activation of G protein-coupled estrogen receptor induces relaxation via cAMP as well as potentiates contraction via EGFR transactivation in porcine coronary arteries","volume":"13","year":"2018","journal-title":"PLoS One"},{"key":"2023080310500565000_10.8.ENEURO.0071-23.2023.143","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2006.09.002"}],"container-title":["eneuro"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1523\/ENEURO.0071-23.2023","content-type":"unspecified","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1523\/ENEURO.0071-23.2023","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T13:51:19Z","timestamp":1691070679000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eneuro.org\/lookup\/doi\/10.1523\/ENEURO.0071-23.2023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,24]]},"references-count":143,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2023,8,3]]},"published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1523\/ENEURO.0071-23.2023"],"URL":"https:\/\/doi.org\/10.1523\/eneuro.0071-23.2023","relation":{},"ISSN":["2373-2822"],"issn-type":[{"value":"2373-2822","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,24]]}}}