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This late wave of activity, central to major theories of consciousness, is thought to be driven by the prefrontal cortex (PFC), responsible for \u201cigniting\u201d it. Here we analyzed two electrophysiological studies in mice performing different stimulus detection tasks and characterized neural activity profiles in three key cortical regions: V1, posterior parietal cortex (PPC), and PFC. We then developed a minimal network model, constrained by known connectivity between these regions, reproducing the spatiotemporal propagation of visual- and report-related activity. Remarkably, while PFC was indeed necessary to generate report-related activity in V1, this occurred only through the mediation of PPC. PPC, and not PFC, had the final veto in enabling the report-related late wave of V1 activity.<\/jats:p>","DOI":"10.1523\/eneuro.0191-24.2024","type":"journal-article","created":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T13:50:42Z","timestamp":1726062642000},"page":"ENEURO.0191-24.2024","source":"Crossref","is-referenced-by-count":1,"title":["The Neural and Computational Architecture of Feedback Dynamics in Mouse Cortex during Stimulus Report"],"prefix":"10.1523","volume":"11","author":[{"given":"Simone","family":"Ciceri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9781-848X","authenticated-orcid":false,"given":"Matthijs N.","family":"Oude Lohuis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4150-3486","authenticated-orcid":false,"given":"Vivi","family":"Rottsch\u00e4fer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8328-1175","authenticated-orcid":false,"given":"Cyriel M. 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