{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T21:03:24Z","timestamp":1776891804983,"version":"3.51.2"},"reference-count":50,"publisher":"Society for Neuroscience","issue":"2","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"vor","delay-in-days":191,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["220101\/Z\/20\/Z"],"award-info":[{"award-number":["220101\/Z\/20\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"name":"UKRI | Biotechnology and Biological Sciences Research Council","award":["BB\/P000959\/1"],"award-info":[{"award-number":["BB\/P000959\/1"]}]},{"name":"UKRI | Biotechnology and Biological Sciences Research Council","award":["BB\/R017336\/1"],"award-info":[{"award-number":["BB\/R017336\/1"]}]}],"content-domain":{"domain":["eneuro.org"],"crossmark-restriction":true},"short-container-title":["eNeuro"],"accepted":{"date-parts":[[2025,12,4]]},"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:p>The cerebellum is well established in subsecond motor timing, but its role in suprasecond interval timing remains unclear. Here, we investigated how cerebellar output influences time estimation over longer timescales. Male rats performed a nose-poke interval timing task in which reward availability could be predicted either from a fixed 2.5\u2005s auditory cue (cued trials) or had to be estimated internally during uncued 3.5\u2005s trials that demanded self-timing. Chemogenetic inhibition of the lateral cerebellar nucleus (LCN) produced bidirectional effects: delayed action initiation in predictable trials and premature (\u223c100\u2013160\u2005ms) responses when self-timing was required. Despite a slowing of movement, overall task success rates remained unchanged. Because motor slowing is likely to lead to later, not earlier, action initiation, these results implicate the LCN in computing internal time estimates. These findings demonstrate that the cerebellum integrates motor and cognitive processes for suprasecond timing, with differential effects on externally guided and self-generated timing.<\/jats:p>","DOI":"10.1523\/eneuro.0198-25.2025","type":"journal-article","created":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T18:50:13Z","timestamp":1769107813000},"page":"ENEURO.0198-25.2025","update-policy":"https:\/\/doi.org\/10.1523\/eneuro.crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Bidirectional Cerebellar Control of Suprasecond Timing in 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