{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T18:19:26Z","timestamp":1761675566669,"version":"build-2065373602"},"reference-count":42,"publisher":"Society for Neuroscience","issue":"10","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":182,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000065","name":"HHS | NIH | National Institute of Neurological Disorders and Stroke","doi-asserted-by":"crossref","award":["R01NS134772","P50 NS123103"],"award-info":[{"award-number":["R01NS134772","P50 NS123103"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Oregon Medical Research Foundation"},{"name":"OHSU Parkinson's Disease Center Pilot Grant"}],"content-domain":{"domain":["eneuro.org"],"crossmark-restriction":true},"short-container-title":["eNeuro"],"accepted":{"date-parts":[[2025,10,3]]},"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:p>The ability to inhibit and adapt our behavior in response to changing stimuli is a critical component of everyday life. Individuals with Parkinson\u2019s disease (PD) may struggle to inhibit behavior, particularly in the presence of dopaminergic therapy, which can result in impulsive behavior. Impulse control disorders are often operationalized in the laboratory using motor inhibition tasks. However, deficits of motor inhibition tasks are not always observed in PD, perhaps because of the nature of the motor inhibition that is engaged in typical tasks (e.g., suppression of incipient movement such as a button press). We employed a novel continuous movement stop task to investigate planned and unplanned motor inhibition during ongoing movement. EEG was recorded during task performance from individuals with PD (OFF and ON dopaminergic medication) and age-matched healthy controls (HC). Participants were of any sex. We found that the time it took for participants to stop a continuous movement was impaired (i.e., longer) in PD patients ON medication compared with both patients OFF medication and HC. This finding was accompanied by diminished midfrontal theta power following the stop signal in PD (ON and OFF) compared with HC. Additionally, an increase in midfrontal beta power was observed, which was higher in unplanned stopping compared with planned for all groups. However, this increase in beta occurred late\u2014after the time of outright stopping. Together, these findings demonstrate that stopping ongoing movements was impaired in PD patients ON medication and theta and beta power play distinct roles in inhibition of movement.<\/jats:p>","DOI":"10.1523\/eneuro.0286-25.2025","type":"journal-article","created":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T17:50:20Z","timestamp":1760118620000},"page":"ENEURO.0286-25.2025","update-policy":"https:\/\/doi.org\/10.1523\/eneuro.crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Electrophysiological Signatures of Planned and Unplanned Continuous Movement Termination in Parkinson\u2019s Disease"],"prefix":"10.1523","volume":"12","author":[{"given":"Apoorva","family":"Karekal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelsey","family":"Schultz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander 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