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This report documents, in an animal model, the efficacy of a simple nontraumatic assay of normal ear function in predicting vulnerability to acoustic injury. The assay measures the strength of a sound-evoked neuronal feedback pathway to the inner ear, the olivocochlear efferents, by examining otoacoustic emissions created by the normal ear, which can be measured with a microphone in the external ear. Reflex strength was inversely correlated with the degree of hearing loss after subsequent noise exposure. These data suggest that one function of the olivocochlear efferent system is to protect the ear from acoustic injury. This assay, or a simple modification of it, could be applied to human populations to screen for individuals most at risk in noisy environments.<\/jats:p>","DOI":"10.1523\/jneurosci.20-12-04701.2000","type":"journal-article","created":{"date-parts":[[2018,4,4]],"date-time":"2018-04-04T19:25:44Z","timestamp":1522869944000},"page":"4701-4707","source":"Crossref","is-referenced-by-count":260,"title":["Predicting Vulnerability to Acoustic Injury with a Noninvasive Assay of Olivocochlear Reflex Strength"],"prefix":"10.1523","volume":"20","author":[{"given":"St\u00e9phane F.","family":"Maison","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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