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However, it is still not known to what extent different cortical networks may differ in their sensitivity to such internally generated neurofeedback (NF). Here, we compare NF efficacy across six cortical regions including: early and high-order visual areas and the posterior parietal lobe, a prominent node of the default mode network (DMN). Our results reveal a consistent difference in NF activation across these areas. Sham controls ruled out a role of attention\/arousal in these effects. These differences are suggestive of a relationship to the relative reliance on intrinsic information, moving from early visual cortex (lowest) to the DMN (highest). Interestingly, the visual parahippocampal place area showed NF activation closer to the DMN node. The results are compatible with the notion of the DMN as an intrinsically oriented system.<\/jats:p>","DOI":"10.1523\/jneurosci.3098-14.2015","type":"journal-article","created":{"date-parts":[[2015,2,11]],"date-time":"2015-02-11T18:29:28Z","timestamp":1423679368000},"page":"2588-2595","source":"Crossref","is-referenced-by-count":39,"title":["Differential Magnetic Resonance Neurofeedback Modulations across Extrinsic (Visual) and Intrinsic (Default-Mode) Nodes of the Human 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