{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:25:41Z","timestamp":1791329141299,"version":"4.3.1"},"reference-count":31,"publisher":"Society for Neuroscience","issue":"1","license":[{"start":{"date-parts":[[2007,7,3]],"date-time":"2007-07-03T00:00:00Z","timestamp":1183420800000},"content-version":"vor","delay-in-days":181,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Neurosci."],"published-print":{"date-parts":[[2007,1,3]]},"abstract":"<jats:p>Several functional areas are proposed to reside in human lateral occipitotemporal cortex, including the motion-selective human homolog of macaque area MT (hMT), object-form-selective lateral occipital complex (LO), and body-selective extrastriate body area (EBA). Indeed, several functional magnetic resonance imaging (fMRI) studies have reported significant activation overlap among these regions. The standard interpretation of this overlap would be that the common areas of activation reflect engagement of common neural systems. Alternatively, motion, object form, and body form may be processed independently within this general region. To distinguish these possibilities, we first analyzed the lateral occipitotemporal responses to motion, objects, bodies, and body parts with whole-brain group-average analyses and within-subjects functional region of interest (ROI) analyses. The activations elicited by these stimuli, each relative to a matched control, overlapped substantially in the group analysis. When hMT, LO, and EBA were defined functionally within subjects, each ROI in each hemisphere (except right-hemisphere hMT) showed significant selectivity for motion, intact objects, bodies, and body parts, although only the peak voxel of each region was tested. In contrast, multi-voxel analyses of variations in selectivity patterns revealed that visual motion, object form, and the form of the human body elicited three relatively independent patterns of fMRI activity in lateral occipitotemporal cortex. Multi-voxel approaches, in contrast to other methods, can reveal the functional significance of overlapping fMRI activity in extrastriate cortex and, by extension, elsewhere in the brain.<\/jats:p>","DOI":"10.1523\/jneurosci.3619-06.2007","type":"journal-article","created":{"date-parts":[[2007,1,4]],"date-time":"2007-01-04T14:05:42Z","timestamp":1167919542000},"page":"226-233","source":"Crossref","is-referenced-by-count":165,"title":["Functional Magnetic Resonance Imaging Investigation of Overlapping Lateral Occipitotemporal Activations Using Multi-Voxel Pattern Analysis"],"prefix":"10.1523","volume":"27","author":[{"given":"Paul E.","family":"Downing","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison J.","family":"Wiggett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marius 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